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The map label for this gene is yngJ [H]

Identifier: 85375813

GI number: 85375813

Start: 3010329

End: 3011399

Strand: Reverse

Name: yngJ [H]

Synonym: ELI_14930

Alternate gene names: 85375813

Gene position: 3011399-3010329 (Counterclockwise)

Preceding gene: 85375814

Following gene: 85375812

Centisome position: 98.66

GC content: 64.99

Gene sequence:

>1071_bases
ATGGCAGTTCTCAACGAAGAACAGGAAATGCTGCGCGACATGGCGCGCGACTGGGCCACCAACGAAAGCCCGGTGACCGA
GTTCCGCAAGGTCCGCGCAAGCGGCGAGCCCCACGCTTACGACAAGGATGCCTATGCCACGATGGCCGAGATGGGCTGGG
CCGGGGTCATCATCCCGGAAGACCACGGCGGTTCGGATTTCGGCTTCATGTCGGCTGGTCTCGTGGTCGAGGAACTCGGC
AAGACGCTGACCGCCAGCCCGCTGGCCGCCACGACCATCGCGGCCAGCGCAATCGTGCTGGGCGGCAGCGAGGAGCAGAA
GGCCAAGTGGCTGCCCAGGCTTGCCAGCGGCGAGACGGTGGCAACGCTGGCGGTCGACGAGGGCGCACATCACGATCCGA
GCACGATCGAGACGAGCGTCTCGGGCGGCAAGTTGACCGGCAAGAAGGCCTTCGTCCACGAAGCGCATGGTGCGGACCTG
TTCGTGGTCGCCGCGAAAGACGGGCTCTATCTCGTCGAGAAAAGTGATGGCGTTTCGCTCACCACGCGCAAGCTCACCGA
TCAGCGCAGCCATGCCGACGTGAGTTTCGACGGTGCGGCGGCGGACAAGCTCGCTGGTGGCGGCGACAGCCTGCTCGACG
ATGTGCTCGACCGGGCACGCGTGCTGACCGCAGCCGAAATGCTCGGAATGGCGCAGCAGGTCTTCGACACCACGCTCGAT
TATCTGAAGCAGCGCGTGCAGTTCAACCAGGTGCTCGCCACCTTCCAGGCACTGCAGCACCGCATGGCCGACCTCTTCGC
CGATCTCGCCCAGATGCGCAGCGCGGTCGAGGCAGGCCTGCAGGCGGTCGATGGCGGCTTCGGGGTCGCGCGTGCGGCAA
CCATCGCCAAAGCGGAGGCCAACCGCGTCATGCACAAAATGGCGAACGAGGGCATCCAGCTGCATGGCGGTATCGGCATG
ACCGACGAATACGACGTCGGCTTCTACCTCAAGCGCGCCCGCGTGCTCGAAGCGAGCTTCGGCTCGTCGGGATATCTCAA
GGACCGCTTCGCGAAGCTGTCGAGTTACTAG

Upstream 100 bases:

>100_bases
CACGACGATCTACGGCGGCTCGACCGAAATCCAGAACAACATCATTTCCAAGCGTGTCCTTGGCATGCTGGATCACCAGT
AAGAGAGGGGAGCTCGAACA

Downstream 100 bases:

>100_bases
AGACCTTCATGTAGAGACCTGCATGGCATTTTTGCCACATGCTGGTCGAAAATGCGGAATAATCTGTCAACCCAACCCGC
ACGTCTTGAAATGAATCGCG

Product: acyl-CoA dehydrogenase family protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MAVLNEEQEMLRDMARDWATNESPVTEFRKVRASGEPHAYDKDAYATMAEMGWAGVIIPEDHGGSDFGFMSAGLVVEELG
KTLTASPLAATTIAASAIVLGGSEEQKAKWLPRLASGETVATLAVDEGAHHDPSTIETSVSGGKLTGKKAFVHEAHGADL
FVVAAKDGLYLVEKSDGVSLTTRKLTDQRSHADVSFDGAAADKLAGGGDSLLDDVLDRARVLTAAEMLGMAQQVFDTTLD
YLKQRVQFNQVLATFQALQHRMADLFADLAQMRSAVEAGLQAVDGGFGVARAATIAKAEANRVMHKMANEGIQLHGGIGM
TDEYDVGFYLKRARVLEASFGSSGYLKDRFAKLSSY

Sequences:

>Translated_356_residues
MAVLNEEQEMLRDMARDWATNESPVTEFRKVRASGEPHAYDKDAYATMAEMGWAGVIIPEDHGGSDFGFMSAGLVVEELG
KTLTASPLAATTIAASAIVLGGSEEQKAKWLPRLASGETVATLAVDEGAHHDPSTIETSVSGGKLTGKKAFVHEAHGADL
FVVAAKDGLYLVEKSDGVSLTTRKLTDQRSHADVSFDGAAADKLAGGGDSLLDDVLDRARVLTAAEMLGMAQQVFDTTLD
YLKQRVQFNQVLATFQALQHRMADLFADLAQMRSAVEAGLQAVDGGFGVARAATIAKAEANRVMHKMANEGIQLHGGIGM
TDEYDVGFYLKRARVLEASFGSSGYLKDRFAKLSSY
>Mature_355_residues
AVLNEEQEMLRDMARDWATNESPVTEFRKVRASGEPHAYDKDAYATMAEMGWAGVIIPEDHGGSDFGFMSAGLVVEELGK
TLTASPLAATTIAASAIVLGGSEEQKAKWLPRLASGETVATLAVDEGAHHDPSTIETSVSGGKLTGKKAFVHEAHGADLF
VVAAKDGLYLVEKSDGVSLTTRKLTDQRSHADVSFDGAAADKLAGGGDSLLDDVLDRARVLTAAEMLGMAQQVFDTTLDY
LKQRVQFNQVLATFQALQHRMADLFADLAQMRSAVEAGLQAVDGGFGVARAATIAKAEANRVMHKMANEGIQLHGGIGMT
DEYDVGFYLKRARVLEASFGSSGYLKDRFAKLSSY

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=27.9255319148936, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=28.1818181818182, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4501859, Length=384, Percent_Identity=25.78125, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI7656849, Length=370, Percent_Identity=28.3783783783784, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=25.1989389920424, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI187960098, Length=371, Percent_Identity=24.5283018867925, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557231, Length=371, Percent_Identity=24.5283018867925, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI21361497, Length=339, Percent_Identity=26.2536873156342, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=23.4972677595628, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI7669494, Length=323, Percent_Identity=26.0061919504644, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4503943, Length=365, Percent_Identity=23.8356164383562, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786223, Length=364, Percent_Identity=26.0989010989011, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=354, Percent_Identity=31.638418079096, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=28.3819628647215, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=28.6486486486486, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=34.9137931034483, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=28.7272727272727, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=347, Percent_Identity=27.3775216138329, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=25.4742547425474, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=26.5193370165746, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=378, Percent_Identity=25.1322751322751, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=314, Percent_Identity=24.5222929936306, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=353, Percent_Identity=23.5127478753541, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=27.9132791327913, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24666513, Length=327, Percent_Identity=27.217125382263, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=26.7379679144385, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=25.1351351351351, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=23.4501347708895, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19920834, Length=356, Percent_Identity=26.123595505618, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 38053; Mature: 37922

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLNEEQEMLRDMARDWATNESPVTEFRKVRASGEPHAYDKDAYATMAEMGWAGVIIPE
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEC
DHGGSDFGFMSAGLVVEELGKTLTASPLAATTIAASAIVLGGSEEQKAKWLPRLASGETV
CCCCCCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCEE
ATLAVDEGAHHDPSTIETSVSGGKLTGKKAFVHEAHGADLFVVAAKDGLYLVEKSDGVSL
EEEEECCCCCCCCCHHEECCCCCCCCCCHHHEEECCCCCEEEEEECCCEEEEECCCCCEE
TTRKLTDQRSHADVSFDGAAADKLAGGGDSLLDDVLDRARVLTAAEMLGMAQQVFDTTLD
EHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKQRVQFNQVLATFQALQHRMADLFADLAQMRSAVEAGLQAVDGGFGVARAATIAKAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NRVMHKMANEGIQLHGGIGMTDEYDVGFYLKRARVLEASFGSSGYLKDRFAKLSSY
HHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
AVLNEEQEMLRDMARDWATNESPVTEFRKVRASGEPHAYDKDAYATMAEMGWAGVIIPE
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEC
DHGGSDFGFMSAGLVVEELGKTLTASPLAATTIAASAIVLGGSEEQKAKWLPRLASGETV
CCCCCCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCEE
ATLAVDEGAHHDPSTIETSVSGGKLTGKKAFVHEAHGADLFVVAAKDGLYLVEKSDGVSL
EEEEECCCCCCCCCHHEECCCCCCCCCCHHHEEECCCCCEEEEEECCCEEEEECCCCCEE
TTRKLTDQRSHADVSFDGAAADKLAGGGDSLLDDVLDRARVLTAAEMLGMAQQVFDTTLD
EHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKQRVQFNQVLATFQALQHRMADLFADLAQMRSAVEAGLQAVDGGFGVARAATIAKAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NRVMHKMANEGIQLHGGIGMTDEYDVGFYLKRARVLEASFGSSGYLKDRFAKLSSY
HHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]