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The map label for this gene is ppa [H]

Identifier: 85375678

GI number: 85375678

Start: 2862611

End: 2863141

Strand: Reverse

Name: ppa [H]

Synonym: ELI_14255

Alternate gene names: 85375678

Gene position: 2863141-2862611 (Counterclockwise)

Preceding gene: 85375686

Following gene: 85375675

Centisome position: 93.8

GC content: 61.77

Gene sequence:

>531_bases
ATGCGCATCGACAAGATCCCCACCGGCAGCAATCCCCCCGAAGACCTCAACGTCATCATCGAAGTCCCGACCGGTGGCGA
ACCGGTCAAGTACGAATTCGACAAGGCAAGCGGTGCGCTGTTCGTCGACCGTATCCTGCACACGCCGATGCGCTATCCGG
CCAATTACGGCTTCATCCCGCACACCCTGTCGCCCGACGGCGATCCGCTCGACGCGCTGGTCATCGCGCGCAGCCCGTTC
ATTGCCGGCTGCGTCGTGCGATCACGCCCGATCGGCGTGCTCAACCTCGAGGACGAGCATGGCGGCGACGAGAAGCTGAT
CTGCGTGCCCGTCGATACGACCTTCCCGTATTATTCGGATGTCGGGGAAACCAAGGACCTGCCGTCGATCATTTTTCAGC
AGATCGAGCACTTTTTTACCCACTACAAGGATCTCGAGGCCGAAAAGTGGGTCCGGATCGGCAAATGGGGCGACGCGGCC
GAAGCGCGGCAGATCGTGCGCGAAGCGATCGAACGCGCGGCGAAAGCCTAG

Upstream 100 bases:

>100_bases
CCACCCGATACAGTATCGGACGATCATCGGGTGGTTGGGAGGGGGAGACGGGCCGGCACCGAGGTCAGGCGGATGCCTGA
CCGCATCCGAAGGACAAACA

Downstream 100 bases:

>100_bases
TATTCGGAAGGCTTGGAGGAATCGAGCAGATCGGCGCTGTCGTCGGCCTCTCCCTGGCGCTCCTTCTCGACCATCTGCGC
AATCTCGTCGGTCGCCGAAA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRIDKIPTGSNPPEDLNVIIEVPTGGEPVKYEFDKASGALFVDRILHTPMRYPANYGFIPHTLSPDGDPLDALVIARSPF
IAGCVVRSRPIGVLNLEDEHGGDEKLICVPVDTTFPYYSDVGETKDLPSIIFQQIEHFFTHYKDLEAEKWVRIGKWGDAA
EARQIVREAIERAAKA

Sequences:

>Translated_176_residues
MRIDKIPTGSNPPEDLNVIIEVPTGGEPVKYEFDKASGALFVDRILHTPMRYPANYGFIPHTLSPDGDPLDALVIARSPF
IAGCVVRSRPIGVLNLEDEHGGDEKLICVPVDTTFPYYSDVGETKDLPSIIFQQIEHFFTHYKDLEAEKWVRIGKWGDAA
EARQIVREAIERAAKA
>Mature_176_residues
MRIDKIPTGSNPPEDLNVIIEVPTGGEPVKYEFDKASGALFVDRILHTPMRYPANYGFIPHTLSPDGDPLDALVIARSPF
IAGCVVRSRPIGVLNLEDEHGGDEKLICVPVDTTFPYYSDVGETKDLPSIIFQQIEHFFTHYKDLEAEKWVRIGKWGDAA
EARQIVREAIERAAKA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=173, Percent_Identity=48.5549132947977, Blast_Score=177, Evalue=3e-46,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19632; Mature: 19632

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDKIPTGSNPPEDLNVIIEVPTGGEPVKYEFDKASGALFVDRILHTPMRYPANYGFIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
HTLSPDGDPLDALVIARSPFIAGCVVRSRPIGVLNLEDEHGGDEKLICVPVDTTFPYYSD
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCC
VGETKDLPSIIFQQIEHFFTHYKDLEAEKWVRIGKWGDAAEARQIVREAIERAAKA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIDKIPTGSNPPEDLNVIIEVPTGGEPVKYEFDKASGALFVDRILHTPMRYPANYGFIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
HTLSPDGDPLDALVIARSPFIAGCVVRSRPIGVLNLEDEHGGDEKLICVPVDTTFPYYSD
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCC
VGETKDLPSIIFQQIEHFFTHYKDLEAEKWVRIGKWGDAAEARQIVREAIERAAKA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]