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The map label for this gene is purE [H]

Identifier: 85375543

GI number: 85375543

Start: 2737056

End: 2737511

Strand: Reverse

Name: purE [H]

Synonym: ELI_13580

Alternate gene names: 85375543

Gene position: 2737511-2737056 (Counterclockwise)

Preceding gene: 85375544

Following gene: 85375542

Centisome position: 89.68

GC content: 68.86

Gene sequence:

>456_bases
ATGGGCAGCCAGTCCGACTGGCCGACGATGCAATGCGCCGCCGAGGTGCTCGACGAGCTGGAAGTGGCTTACGACGCGCG
GATCGTATCCGCGCACCGCACGCCCGACCGGATGGCGGATTTTGCCAGAGGGGCCGAGGCGGAAGGCTTCAAGGTCATCA
TCGCCGGCGCGGGCGGCGCGGCGCATCTGCCGGGGATGGTCGCAGCGATGACGCATCTGCCGGTGCTGGGCATACCGGTG
CAATCCAAGGCGCTGTCGGGCATGGATAGCCTGCTCTCGATCGTGCAGATGCCTGCCGGGGTTCCGACCGGCACGCTCGC
CATCGGCGAGGCGGGCGCGACCAATGCGGGGCTGCTGGCTGCGAGTATCCTCGCTACATCGGACGACGCGCTGGCCGTGC
GCTTGAAGGCGTGGCGCGCCGCACGCAGCGAGGCTGTCGCAGAGAAGCCGGAATAG

Upstream 100 bases:

>100_bases
CCAGCCGATCATCTACCAATTCGACGACCGGATGCAGCCGGGCGAGCGCTATTACCTGAAGGACAGCTGAGGCATGGGCG
GAGCTAAAGTCGCTATCATC

Downstream 100 bases:

>100_bases
CCATGATCAAGCCGGGGGGGACAATCGGGATATTGGGCGGCGGCCAACTCGGCCGGATGATGGCGATCGCCGCTGCGCAG
ATGGGCTATCGCTGCATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MGSQSDWPTMQCAAEVLDELEVAYDARIVSAHRTPDRMADFARGAEAEGFKVIIAGAGGAAHLPGMVAAMTHLPVLGIPV
QSKALSGMDSLLSIVQMPAGVPTGTLAIGEAGATNAGLLAASILATSDDALAVRLKAWRAARSEAVAEKPE

Sequences:

>Translated_151_residues
MGSQSDWPTMQCAAEVLDELEVAYDARIVSAHRTPDRMADFARGAEAEGFKVIIAGAGGAAHLPGMVAAMTHLPVLGIPV
QSKALSGMDSLLSIVQMPAGVPTGTLAIGEAGATNAGLLAASILATSDDALAVRLKAWRAARSEAVAEKPE
>Mature_150_residues
GSQSDWPTMQCAAEVLDELEVAYDARIVSAHRTPDRMADFARGAEAEGFKVIIAGAGGAAHLPGMVAAMTHLPVLGIPVQ
SKALSGMDSLLSIVQMPAGVPTGTLAIGEAGATNAGLLAASILATSDDALAVRLKAWRAARSEAVAEKPE

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=151, Percent_Identity=64.2384105960265, Blast_Score=167, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324702, Length=151, Percent_Identity=51.6556291390728, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 15421; Mature: 15290

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSQSDWPTMQCAAEVLDELEVAYDARIVSAHRTPDRMADFARGAEAEGFKVIIAGAGGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCCEEEEEECCCCC
AHLPGMVAAMTHLPVLGIPVQSKALSGMDSLLSIVQMPAGVPTGTLAIGEAGATNAGLLA
HHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
ASILATSDDALAVRLKAWRAARSEAVAEKPE
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSQSDWPTMQCAAEVLDELEVAYDARIVSAHRTPDRMADFARGAEAEGFKVIIAGAGGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCCEEEEEECCCCC
AHLPGMVAAMTHLPVLGIPVQSKALSGMDSLLSIVQMPAGVPTGTLAIGEAGATNAGLLA
HHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
ASILATSDDALAVRLKAWRAARSEAVAEKPE
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]