Click here to switch to the map view.

The map label for this gene is 85375540

Identifier: 85375540

GI number: 85375540

Start: 2734303

End: 2735502

Strand: Reverse

Name: 85375540

Synonym: ELI_13565

Alternate gene names: NA

Gene position: 2735502-2734303 (Counterclockwise)

Preceding gene: 85375541

Following gene: 85375539

Centisome position: 89.62

GC content: 64.17

Gene sequence:

>1200_bases
ATGAAAAAGCGCTACTGGATCCCGCTGCTGGTGCTCGCGATCGCCGCCAGTGCCTTCTTCGCCTTCGCCCCCGGCTTTGC
CGAGCGGGACATGAACCGGATCGACGGGAAACCGCTGCCCGAAGTCAGCGAGGATGCGAAAGCGCTCCACGCCACGCTCG
ATATCGTCGACCTGCACGCCGATACGCTGCTGTGGAAGCGCTCGATGGTCTATGCCGCCGATCGCGGCCATGTCGACCTG
CCCCGGCTAGAAGCGGGCAATGTCGCGGTGCAGGTGTTCTCCAGCGTAACCAAGACACCGACCGACCAGAATTACGACAG
CAATAGCGCCGATGGCGACAACATTACGCTGCTGGCAGTGGGCCAGTTGCAGCCGGTGCGGACCTGGTCCTCGCTGCTGG
AACGGACGCTCTATCATGCGGAAAAGCTGGAACGCGCGGCTCGCGAGTCGAACGGCATGATTATCCCGATCGAAACGCCC
AACGATCTCGACGGCGTATTCGGTCACCGCCGCATAAAGGGGCCGCAATTCGTCGGCGCGCTGCTCAGCGTCGAGGGCCT
GCACAACCTGGAAGGCGATGCCGCCAACCTCGAGCGGATATACGATGCCGGGGTGCGGATGGCCGGGCTGACCCATTTCT
TCGACAACGAACTCGCCGGATCGATGCACGGGATCGAGAAAGGCGGGCTGACCCCCTTCGGCCGCAATATCGTGCGGCGG
ATGGAAGAGATGGGCATGATCGTCGACATCGCGCATCTCAGCCACACCGGTGTCGCCGAAGTGCTGGCGATGGCGCGGCG
GCCGGTCGTCTCCAGCCATGGCGGCGTGCAGGCGACCTGCAAGGTCAATCGCAACCTCACCGACGCGGAAATCCGTGGCC
TCGCCGCGACCGGCGGAATCATAGGCGTCGGCTATTGGGAAGGCGCGGTCTGCGACACCTCGCCCAAGGCCATTGCCGCG
GCGATGAACCATATCCGCGACCTGGTCGGGATCGAGCATGTCGCGCTCGGCAGCGATTACGACGGCGCGGTCGAGGTGCG
GTTCGACACGTCCAAGCTGGTGCAGGTCACGCAGGCGCTGATGGATGCAGGCTTCAGCGAGCGTGAAATCCGCGCCGTGA
TGGGCGGCAATGCCATCCGCGTGCTGCGCGAAGGGATGAAGCCGCTTGCGGATGTCGCGCAGCCAGCTACCAATTCCTGA

Upstream 100 bases:

>100_bases
ACGCGCCCGGCCCCGACTGGCGCGAGATCGCGCGTGACGAATACGAGGCCGAAGATGGTCGACCTGCCTTCTCTTTCGTC
ACCTTTCTGAGAGCAGAGCG

Downstream 100 bases:

>100_bases
TGCGCTGGCTCGACCATCGAAACCCCGTCCCTGAATCCTTGCGCGGTGCCATTATCGCGCTGGGCAATTTCGACGGCTTC
CATCGCGGCCACCAGGCGGT

Product: renal dipeptidase family protein

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKRYWIPLLVLAIAASAFFAFAPGFAERDMNRIDGKPLPEVSEDAKALHATLDIVDLHADTLLWKRSMVYAADRGHVDL
PRLEAGNVAVQVFSSVTKTPTDQNYDSNSADGDNITLLAVGQLQPVRTWSSLLERTLYHAEKLERAARESNGMIIPIETP
NDLDGVFGHRRIKGPQFVGALLSVEGLHNLEGDAANLERIYDAGVRMAGLTHFFDNELAGSMHGIEKGGLTPFGRNIVRR
MEEMGMIVDIAHLSHTGVAEVLAMARRPVVSSHGGVQATCKVNRNLTDAEIRGLAATGGIIGVGYWEGAVCDTSPKAIAA
AMNHIRDLVGIEHVALGSDYDGAVEVRFDTSKLVQVTQALMDAGFSEREIRAVMGGNAIRVLREGMKPLADVAQPATNS

Sequences:

>Translated_399_residues
MKKRYWIPLLVLAIAASAFFAFAPGFAERDMNRIDGKPLPEVSEDAKALHATLDIVDLHADTLLWKRSMVYAADRGHVDL
PRLEAGNVAVQVFSSVTKTPTDQNYDSNSADGDNITLLAVGQLQPVRTWSSLLERTLYHAEKLERAARESNGMIIPIETP
NDLDGVFGHRRIKGPQFVGALLSVEGLHNLEGDAANLERIYDAGVRMAGLTHFFDNELAGSMHGIEKGGLTPFGRNIVRR
MEEMGMIVDIAHLSHTGVAEVLAMARRPVVSSHGGVQATCKVNRNLTDAEIRGLAATGGIIGVGYWEGAVCDTSPKAIAA
AMNHIRDLVGIEHVALGSDYDGAVEVRFDTSKLVQVTQALMDAGFSEREIRAVMGGNAIRVLREGMKPLADVAQPATNS
>Mature_399_residues
MKKRYWIPLLVLAIAASAFFAFAPGFAERDMNRIDGKPLPEVSEDAKALHATLDIVDLHADTLLWKRSMVYAADRGHVDL
PRLEAGNVAVQVFSSVTKTPTDQNYDSNSADGDNITLLAVGQLQPVRTWSSLLERTLYHAEKLERAARESNGMIIPIETP
NDLDGVFGHRRIKGPQFVGALLSVEGLHNLEGDAANLERIYDAGVRMAGLTHFFDNELAGSMHGIEKGGLTPFGRNIVRR
MEEMGMIVDIAHLSHTGVAEVLAMARRPVVSSHGGVQATCKVNRNLTDAEIRGLAATGGIIGVGYWEGAVCDTSPKAIAA
AMNHIRDLVGIEHVALGSDYDGAVEVRFDTSKLVQVTQALMDAGFSEREIRAVMGGNAIRVLREGMKPLADVAQPATNS

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=236, Percent_Identity=30.5084745762712, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI189458885, Length=407, Percent_Identity=24.0786240786241, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4758190, Length=407, Percent_Identity=24.0786240786241, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI193211608, Length=238, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI193211610, Length=238, Percent_Identity=29.8319327731092, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI161083233, Length=344, Percent_Identity=29.6511627906977, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI221475880, Length=416, Percent_Identity=26.2019230769231, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281362638, Length=326, Percent_Identity=29.1411042944785, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281362636, Length=326, Percent_Identity=29.1411042944785, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 43140; Mature: 43140

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRYWIPLLVLAIAASAFFAFAPGFAERDMNRIDGKPLPEVSEDAKALHATLDIVDLHA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DTLLWKRSMVYAADRGHVDLPRLEAGNVAVQVFSSVTKTPTDQNYDSNSADGDNITLLAV
HHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
GQLQPVRTWSSLLERTLYHAEKLERAARESNGMIIPIETPNDLDGVFGHRRIKGPQFVGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCHHHHHH
LLSVEGLHNLEGDAANLERIYDAGVRMAGLTHFFDNELAGSMHGIEKGGLTPFGRNIVRR
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MEEMGMIVDIAHLSHTGVAEVLAMARRPVVSSHGGVQATCKVNRNLTDAEIRGLAATGGI
HHHCCCEEEEHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHCEEECCCE
IGVGYWEGAVCDTSPKAIAAAMNHIRDLVGIEHVALGSDYDGAVEVRFDTSKLVQVTQAL
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECHHHHHHHHHHH
MDAGFSEREIRAVMGGNAIRVLREGMKPLADVAQPATNS
HHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKRYWIPLLVLAIAASAFFAFAPGFAERDMNRIDGKPLPEVSEDAKALHATLDIVDLHA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DTLLWKRSMVYAADRGHVDLPRLEAGNVAVQVFSSVTKTPTDQNYDSNSADGDNITLLAV
HHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
GQLQPVRTWSSLLERTLYHAEKLERAARESNGMIIPIETPNDLDGVFGHRRIKGPQFVGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCHHHHHH
LLSVEGLHNLEGDAANLERIYDAGVRMAGLTHFFDNELAGSMHGIEKGGLTPFGRNIVRR
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MEEMGMIVDIAHLSHTGVAEVLAMARRPVVSSHGGVQATCKVNRNLTDAEIRGLAATGGI
HHHCCCEEEEHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHCEEECCCE
IGVGYWEGAVCDTSPKAIAAAMNHIRDLVGIEHVALGSDYDGAVEVRFDTSKLVQVTQAL
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECHHHHHHHHHHH
MDAGFSEREIRAVMGGNAIRVLREGMKPLADVAQPATNS
HHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]