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The map label for this gene is qor [H]

Identifier: 85375464

GI number: 85375464

Start: 2655762

End: 2656772

Strand: Direct

Name: qor [H]

Synonym: ELI_13185

Alternate gene names: 85375464

Gene position: 2655762-2656772 (Clockwise)

Preceding gene: 85375459

Following gene: 85375465

Centisome position: 87.01

GC content: 66.37

Gene sequence:

>1011_bases
ATGGTGGATACGCTTCCCAAGAATATGACGGCCATCGGCATGGACCGGCCCGGCGCGCCGGACGTGCTGCGAACCGAGAC
CGCAGATGTGCCGCAGCCCGGCCCCGGCGAGGTGCTGGTCCAAGTTGCTTGGGCCGGGGTCAATCGGCCCGACTGCATCC
AGCGCGCGGGCCATTATCCCGCCCCTCCGGGAGCTTCGCCGATCCTCGGGCTCGAGGTCTCGGGCCGCATCATCGCGCTC
GGCGATGGCGTACCCGAAACGCTGCTCGGCGAGACCGTCTGCGCGCTGACCCCGGGCGGCGGCTATGCCGAATATTGCAA
GGTGCCGGTCGGCCACTGCCTGCCGGTTCCAGACGACCTGCCGCTCGACCAGGCGGCCGCTGTTCCTGAAACCCTGTTCA
CTGTCTGGCACAATGTGTTCCAGCGCGGGTGCGCGCGTGAGGGCGAAACGCTGCTGGTACACGGCGGCACCAGCGGGATC
GGCACCATGGCGACGATGCTCGCCAAGGCTTTCGACATGCAGGTCATCGTGACGTGCGGCGACGATGCCAAGTGCGAGGC
TGCGCGCGAGGTCGGGGCGGATCATGCGATCAATTACAAAACCCAGGACTTCGTCGAGGAAGTGAAGGCGATCACGCGGG
GCAAGGGCGTGGAGGTCGTGCTCGACATGGTCTCGGGCGATTATGTCGCGCGCAACCTCAAGTGCCTGGCAGAAGACGGG
CGGCATGTGACGATCGCGGTGCTCGGCGGAATGCAGGCAGAGCTCAACATGGCCTTCATCATGAGCCGTCGCCTGACGCT
GACAGGCTCGACTCTCAGGCCGCGCAGCGACGCTTTCAAGACCGCGCTTTGCGACGAGATCGGCCAGATCGCCTGGCCGC
TCATCTTGAACGGCACGATCCGCCCGGTCATGGACCGCAGCTTCCCGCTTGCCGATGCGGCGTCCGCCCATGCGCGGATG
GAGGCGGGCGATCACATCGGCAAGATCGTGCTGGAGGTTGCCGGTGGGTGA

Upstream 100 bases:

>100_bases
GTCGCCGGGCTGGATGCTTGCTGTCAATACGCCGTAAGGCTAGGTGCCCATCAAAAGAAGAGAACCGGATCGCGTTCTGC
ATCGTGGTGGACAGGAACGA

Downstream 100 bases:

>100_bases
GAAACTGCTCCTTCATGAAGACCCGCGCAGCGGCAATTGCTACAAGATCAAGCTGACCGCCGCGCTCCTGAGCGTGCCCT
TGGATACGCGGCGATACGAC

Product: NADPH quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVDTLPKNMTAIGMDRPGAPDVLRTETADVPQPGPGEVLVQVAWAGVNRPDCIQRAGHYPAPPGASPILGLEVSGRIIAL
GDGVPETLLGETVCALTPGGGYAEYCKVPVGHCLPVPDDLPLDQAAAVPETLFTVWHNVFQRGCAREGETLLVHGGTSGI
GTMATMLAKAFDMQVIVTCGDDAKCEAAREVGADHAINYKTQDFVEEVKAITRGKGVEVVLDMVSGDYVARNLKCLAEDG
RHVTIAVLGGMQAELNMAFIMSRRLTLTGSTLRPRSDAFKTALCDEIGQIAWPLILNGTIRPVMDRSFPLADAASAHARM
EAGDHIGKIVLEVAGG

Sequences:

>Translated_336_residues
MVDTLPKNMTAIGMDRPGAPDVLRTETADVPQPGPGEVLVQVAWAGVNRPDCIQRAGHYPAPPGASPILGLEVSGRIIAL
GDGVPETLLGETVCALTPGGGYAEYCKVPVGHCLPVPDDLPLDQAAAVPETLFTVWHNVFQRGCAREGETLLVHGGTSGI
GTMATMLAKAFDMQVIVTCGDDAKCEAAREVGADHAINYKTQDFVEEVKAITRGKGVEVVLDMVSGDYVARNLKCLAEDG
RHVTIAVLGGMQAELNMAFIMSRRLTLTGSTLRPRSDAFKTALCDEIGQIAWPLILNGTIRPVMDRSFPLADAASAHARM
EAGDHIGKIVLEVAGG
>Mature_336_residues
MVDTLPKNMTAIGMDRPGAPDVLRTETADVPQPGPGEVLVQVAWAGVNRPDCIQRAGHYPAPPGASPILGLEVSGRIIAL
GDGVPETLLGETVCALTPGGGYAEYCKVPVGHCLPVPDDLPLDQAAAVPETLFTVWHNVFQRGCAREGETLLVHGGTSGI
GTMATMLAKAFDMQVIVTCGDDAKCEAAREVGADHAINYKTQDFVEEVKAITRGKGVEVVLDMVSGDYVARNLKCLAEDG
RHVTIAVLGGMQAELNMAFIMSRRLTLTGSTLRPRSDAFKTALCDEIGQIAWPLILNGTIRPVMDRSFPLADAASAHARM
EAGDHIGKIVLEVAGG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=40.0602409638554, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=40.0602409638554, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=27.4924471299094, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=27.4924471299094, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=25.8720930232558, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI18379349, Length=300, Percent_Identity=28.3333333333333, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=29.3929712460064, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI194239676, Length=331, Percent_Identity=25.9818731117825, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI28557745, Length=225, Percent_Identity=33.7777777777778, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI47519420, Length=362, Percent_Identity=27.9005524861878, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=318, Percent_Identity=29.874213836478, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787863, Length=356, Percent_Identity=25.561797752809, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=311, Percent_Identity=30.5466237942122, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17507255, Length=328, Percent_Identity=25.3048780487805, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=25.8823529411765, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24581345, Length=281, Percent_Identity=26.6903914590747, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19920632, Length=308, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330659, Length=308, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35458; Mature: 35458

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDTLPKNMTAIGMDRPGAPDVLRTETADVPQPGPGEVLVQVAWAGVNRPDCIQRAGHYP
CCCCCCCCCEEECCCCCCCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCC
APPGASPILGLEVSGRIIALGDGVPETLLGETVCALTPGGGYAEYCKVPVGHCLPVPDDL
CCCCCCCEEEEEECCEEEEECCCCCHHHHCCEEEEECCCCCHHHHHCCCCCCCCCCCCCC
PLDQAAAVPETLFTVWHNVFQRGCAREGETLLVHGGTSGIGTMATMLAKAFDMQVIVTCG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEEC
DDAKCEAAREVGADHAINYKTQDFVEEVKAITRGKGVEVVLDMVSGDYVARNLKCLAEDG
CCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEEHHCCHHHHHHHHHHHCCC
RHVTIAVLGGMQAELNMAFIMSRRLTLTGSTLRPRSDAFKTALCDEIGQIAWPLILNGTI
CEEEEEEECCCCHHHHHEEHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECCCC
RPVMDRSFPLADAASAHARMEAGDHIGKIVLEVAGG
CHHHCCCCCCCHHHHHHHHHHCCHHHEEEEEEECCC
>Mature Secondary Structure
MVDTLPKNMTAIGMDRPGAPDVLRTETADVPQPGPGEVLVQVAWAGVNRPDCIQRAGHYP
CCCCCCCCCEEECCCCCCCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCC
APPGASPILGLEVSGRIIALGDGVPETLLGETVCALTPGGGYAEYCKVPVGHCLPVPDDL
CCCCCCCEEEEEECCEEEEECCCCCHHHHCCEEEEECCCCCHHHHHCCCCCCCCCCCCCC
PLDQAAAVPETLFTVWHNVFQRGCAREGETLLVHGGTSGIGTMATMLAKAFDMQVIVTCG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEEC
DDAKCEAAREVGADHAINYKTQDFVEEVKAITRGKGVEVVLDMVSGDYVARNLKCLAEDG
CCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEEHHCCHHHHHHHHHHHCCC
RHVTIAVLGGMQAELNMAFIMSRRLTLTGSTLRPRSDAFKTALCDEIGQIAWPLILNGTI
CEEEEEEECCCCHHHHHEEHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECCCC
RPVMDRSFPLADAASAHARMEAGDHIGKIVLEVAGG
CHHHCCCCCCCHHHHHHHHHHCCHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]