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The map label for this gene is aroE [H]

Identifier: 85375425

GI number: 85375425

Start: 2615815

End: 2616696

Strand: Reverse

Name: aroE [H]

Synonym: ELI_12990

Alternate gene names: 85375425

Gene position: 2616696-2615815 (Counterclockwise)

Preceding gene: 85375426

Following gene: 85375424

Centisome position: 85.73

GC content: 65.08

Gene sequence:

>882_bases
ATGAGTATGCCCCCTTCGACAGGCTCACGACAGGCCTACGCCGAAGTCATCGGCGATCCGATCGCGCAGTCCAAATCGCC
GTTGATCCACATGTTCTGGATCGCACAGCTCGGGCTCGATGCCCATTATCGTGCGCAAGCGGTCGCGCCGGAGGCACTGG
CGCAATATCTGTTCGAGCGGAAGGGCGACGCCAACTGGCGCGGCTGCAACGTCACCATGCCGCACAAGCAGGCGGTTCTG
CCGCTGCTCGACCGGCTCGATCCGACGGCCGAGAAGATCGGCGCGGTGAATACCGTGGTGCGCAGCGATGATGGCGTGCT
GACCGGATACAATACCGATGTCGTAGGATTCCTCGAGCCACTGCGAGACGAGCTGTCGGGGCACCACCTGTTCCGCATGA
CGAGGGTCATCGGCACCGGCGGGGCGGCGCGCGCGATCGTCGCCGGGCTTGCCGGGGAAGGCTTCACGATCGTGCTGGCC
GGTCGCGATCCGGAAAAGGCAGCGCGCCTGCTGGAGGAGCTCGGCGGCCCCACCGAACATTTCAACCCGCCGCTATCGCA
TTTTGCCGAAGCAACCGACTTCGCCTTCGACGACCGCGAGCAATGTCTCGATCTCGTCGTCAACGCCTCGCCGCTCGGCA
TGGCGGGACAGCCGCCGCTCGCTTTTGCGATCTCGCACGCACCGCCCGGATCGATCGTCTATGACATTGTGACCGATCCC
ATCGACACCGTGCTGCTGGAGCAGGCGCGCGCGGCGGGATTTCGCACGATCGACGGCCTCGCCATGCTGATCGGTCAGGC
GGCGGAGGCATTCGAGCTGTTCTTCGACGCCGCCCCGCCGCGCGACTTTGACCAAGAGCTGCGCGAAAGGCTTCTCGCAT
GA

Upstream 100 bases:

>100_bases
TGCAGTTGTTCGAGCAGATCATCGGCGACCAGTTTACCGTACTCGGCATGCCGTTGTTGCAGGTTATGGCAGCCCTGCGC
GAGCGCGGCGTCCTACAGGC

Downstream 100 bases:

>100_bases
ATCGACCCAAGATTATCGGGCTCACCGGTTCGATCGGAATGGGCAAGTCGACCGTCGCCGATATGTTCGAGCGTGCCGGC
GTGCCCGTTTTCGATGCCGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSMPPSTGSRQAYAEVIGDPIAQSKSPLIHMFWIAQLGLDAHYRAQAVAPEALAQYLFERKGDANWRGCNVTMPHKQAVL
PLLDRLDPTAEKIGAVNTVVRSDDGVLTGYNTDVVGFLEPLRDELSGHHLFRMTRVIGTGGAARAIVAGLAGEGFTIVLA
GRDPEKAARLLEELGGPTEHFNPPLSHFAEATDFAFDDREQCLDLVVNASPLGMAGQPPLAFAISHAPPGSIVYDIVTDP
IDTVLLEQARAAGFRTIDGLAMLIGQAAEAFELFFDAAPPRDFDQELRERLLA

Sequences:

>Translated_293_residues
MSMPPSTGSRQAYAEVIGDPIAQSKSPLIHMFWIAQLGLDAHYRAQAVAPEALAQYLFERKGDANWRGCNVTMPHKQAVL
PLLDRLDPTAEKIGAVNTVVRSDDGVLTGYNTDVVGFLEPLRDELSGHHLFRMTRVIGTGGAARAIVAGLAGEGFTIVLA
GRDPEKAARLLEELGGPTEHFNPPLSHFAEATDFAFDDREQCLDLVVNASPLGMAGQPPLAFAISHAPPGSIVYDIVTDP
IDTVLLEQARAAGFRTIDGLAMLIGQAAEAFELFFDAAPPRDFDQELRERLLA
>Mature_292_residues
SMPPSTGSRQAYAEVIGDPIAQSKSPLIHMFWIAQLGLDAHYRAQAVAPEALAQYLFERKGDANWRGCNVTMPHKQAVLP
LLDRLDPTAEKIGAVNTVVRSDDGVLTGYNTDVVGFLEPLRDELSGHHLFRMTRVIGTGGAARAIVAGLAGEGFTIVLAG
RDPEKAARLLEELGGPTEHFNPPLSHFAEATDFAFDDREQCLDLVVNASPLGMAGQPPLAFAISHAPPGSIVYDIVTDPI
DTVLLEQARAAGFRTIDGLAMLIGQAAEAFELFFDAAPPRDFDQELRERLLA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=272, Percent_Identity=33.4558823529412, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789675, Length=286, Percent_Identity=32.5174825174825, Blast_Score=103, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320332, Length=173, Percent_Identity=32.9479768786127, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31595; Mature: 31464

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPPSTGSRQAYAEVIGDPIAQSKSPLIHMFWIAQLGLDAHYRAQAVAPEALAQYLFER
CCCCCCCCCHHHHHHHHCCHHHCCCCCEEHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHC
KGDANWRGCNVTMPHKQAVLPLLDRLDPTAEKIGAVNTVVRSDDGVLTGYNTDVVGFLEP
CCCCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCEEECCCCCHHHHHHH
LRDELSGHHLFRMTRVIGTGGAARAIVAGLAGEGFTIVLAGRDPEKAARLLEELGGPTEH
HHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHH
FNPPLSHFAEATDFAFDDREQCLDLVVNASPLGMAGQPPLAFAISHAPPGSIVYDIVTDP
CCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEHHHHCH
IDTVLLEQARAAGFRTIDGLAMLIGQAAEAFELFFDAAPPRDFDQELRERLLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SMPPSTGSRQAYAEVIGDPIAQSKSPLIHMFWIAQLGLDAHYRAQAVAPEALAQYLFER
CCCCCCCCHHHHHHHHCCHHHCCCCCEEHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHC
KGDANWRGCNVTMPHKQAVLPLLDRLDPTAEKIGAVNTVVRSDDGVLTGYNTDVVGFLEP
CCCCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCEEECCCCCHHHHHHH
LRDELSGHHLFRMTRVIGTGGAARAIVAGLAGEGFTIVLAGRDPEKAARLLEELGGPTEH
HHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHH
FNPPLSHFAEATDFAFDDREQCLDLVVNASPLGMAGQPPLAFAISHAPPGSIVYDIVTDP
CCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEHHHHCH
IDTVLLEQARAAGFRTIDGLAMLIGQAAEAFELFFDAAPPRDFDQELRERLLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA