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The map label for this gene is coaE

Identifier: 85375424

GI number: 85375424

Start: 2615228

End: 2615818

Strand: Reverse

Name: coaE

Synonym: ELI_12985

Alternate gene names: 85375424

Gene position: 2615818-2615228 (Counterclockwise)

Preceding gene: 85375425

Following gene: 85375423

Centisome position: 85.7

GC content: 65.82

Gene sequence:

>591_bases
ATGAATCGACCCAAGATTATCGGGCTCACCGGTTCGATCGGAATGGGCAAGTCGACCGTCGCCGATATGTTCGAGCGTGC
CGGCGTGCCCGTTTTCGATGCCGATGCCGAAGTGCGCGCGATGCAGGGGCCGGGCGGCGAACTGCTGCCCGCCATCGAAG
CCGCCTTCCCCGGTTCGACCGGGCCTGAAGGCGTCGACCGCGAGGCCCTGGGCGCGCAGGTTTTCGCCGATGCCACGCTG
CTGGCGAACCTTGAGGCGATCGTGCATCCCGCGGTCGGTGCCAAGCGCGCCGCGTTCCTCGAGCAGCATCACGACAAACC
GATGGTCGTTTTCGACATTCCGCTGCTGTTCGAAAAGGGCGGGCACGCTGCGGTCGATGCGGTCGTGGTGGTGTCTGCTC
CCGCCGAAACGCAGCGTGAACGGGTGCTCGCCCGGCCCGGCATGACGCCGGAGAAGTTCGAACACATCCTCACGCTGCAG
GTGCCCGATGCGGAAAAGCGCGAGCGCGCCGACCATGTCATCGATACGGGACAATCGCTGGAGGCGACCGAGGCTTCGGT
AAAGGCGCTCATCGCCGAACTCGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGCCATGCTGATCGGTCAGGCGGCGGAGGCATTCGAGCTGTTCTTCGACGCCGCCCCGCCGCGCGACTTTGACCAAGAG
CTGCGCGAAAGGCTTCTCGC

Downstream 100 bases:

>100_bases
AGACCGATCCACCATCACACCTCTTGCGACTCGCGCCACAAGGGTGAATAGTGCAGCCAATGCGTGAAATCGTGTTCGAT
ACCGAAACCACCGGCCTCGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MNRPKIIGLTGSIGMGKSTVADMFERAGVPVFDADAEVRAMQGPGGELLPAIEAAFPGSTGPEGVDREALGAQVFADATL
LANLEAIVHPAVGAKRAAFLEQHHDKPMVVFDIPLLFEKGGHAAVDAVVVVSAPAETQRERVLARPGMTPEKFEHILTLQ
VPDAEKRERADHVIDTGQSLEATEASVKALIAELAA

Sequences:

>Translated_196_residues
MNRPKIIGLTGSIGMGKSTVADMFERAGVPVFDADAEVRAMQGPGGELLPAIEAAFPGSTGPEGVDREALGAQVFADATL
LANLEAIVHPAVGAKRAAFLEQHHDKPMVVFDIPLLFEKGGHAAVDAVVVVSAPAETQRERVLARPGMTPEKFEHILTLQ
VPDAEKRERADHVIDTGQSLEATEASVKALIAELAA
>Mature_196_residues
MNRPKIIGLTGSIGMGKSTVADMFERAGVPVFDADAEVRAMQGPGGELLPAIEAAFPGSTGPEGVDREALGAQVFADATL
LANLEAIVHPAVGAKRAAFLEQHHDKPMVVFDIPLLFEKGGHAAVDAVVVVSAPAETQRERVLARPGMTPEKFEHILTLQ
VPDAEKRERADHVIDTGQSLEATEASVKALIAELAA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=194, Percent_Identity=30.4123711340206, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI191252795, Length=194, Percent_Identity=30.4123711340206, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1786292, Length=187, Percent_Identity=34.2245989304813, Blast_Score=84, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17554944, Length=202, Percent_Identity=30.6930693069307, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=32.5, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644728, Length=188, Percent_Identity=32.9787234042553, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658602, Length=203, Percent_Identity=30.5418719211823, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 20632; Mature: 20632

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPKIIGLTGSIGMGKSTVADMFERAGVPVFDADAEVRAMQGPGGELLPAIEAAFPGST
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCEEEECCCCCCHHHHHHHCCCCCC
GPEGVDREALGAQVFADATLLANLEAIVHPAVGAKRAAFLEQHHDKPMVVFDIPLLFEKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCEEEECC
GHAAVDAVVVVSAPAETQRERVLARPGMTPEKFEHILTLQVPDAEKRERADHVIDTGQSL
CCCEEEEEEEEECCCHHHHHHHHHCCCCCHHHHCEEEEEECCCCHHHHHHHHHHCCCCCC
EATEASVKALIAELAA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRPKIIGLTGSIGMGKSTVADMFERAGVPVFDADAEVRAMQGPGGELLPAIEAAFPGST
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCEEEECCCCCCHHHHHHHCCCCCC
GPEGVDREALGAQVFADATLLANLEAIVHPAVGAKRAAFLEQHHDKPMVVFDIPLLFEKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCEEEECC
GHAAVDAVVVVSAPAETQRERVLARPGMTPEKFEHILTLQVPDAEKRERADHVIDTGQSL
CCCEEEEEEEEECCCHHHHHHHHHCCCCCHHHHCEEEEEECCCCHHHHHHHHHHCCCCCC
EATEASVKALIAELAA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA