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The map label for this gene is dnaQ [H]

Identifier: 85375423

GI number: 85375423

Start: 2614479

End: 2615168

Strand: Reverse

Name: dnaQ [H]

Synonym: ELI_12980

Alternate gene names: 85375423

Gene position: 2615168-2614479 (Counterclockwise)

Preceding gene: 85375424

Following gene: 85375422

Centisome position: 85.68

GC content: 63.48

Gene sequence:

>690_bases
ATGCGTGAAATCGTGTTCGATACCGAAACCACCGGCCTCGACCCCAAGACAGGGGACCGGATGGTTGAAATCGGCTGCGT
GGAACTGATGAACCGGGTCCCGACCGGCGAGACCTTCCATGCCTATTACAATCCGGAACGCGACATGCCGCCGGCGGCAG
AGGAAGTACACGGACTGTCCGCCGCCTTCCTGTCCGACAAGCCGCTGTTTCGCGACACGGCGGATGCGCTGCTCGAATTC
CTCGGCGATGCGCCGCTGGTGGCACACAATGCCGGGTTCGATTTCGGCTTTCTCAACACCGAGCTGGAGCTGATCGAGCG
CGAGGCAATCAGCTTGGATCGCATGGTCGATACCGTCCAGATCGCGCGCAAGAAGCACCCCGGCGCCAAGGTGTCGCTCG
ATGCGCTGTGCAGCCGCTACGGCGTCGATCGCAGCCACCGGGTCAAGCACGGCGCGCTGCTCGATGCCGAGTTGCTGGCC
CAGGTCTATGTCGAATTGCTCGGCGGCAGGCAGATTGGGCTCGGCCTCGATCCGGAAGCCGCCGACACCGACCCGTCCGA
AGCTGCGTGGAAGCCGGAAACGGTCGCACGAGCGTTTCGCACACCCCGTCCCCATGCGGCCAGTGCGGAGGAACTGGCCC
GACACAAAGTGTTCCTCGAAGGGATCGAGTCCCCGCTCTGGAACAATTGA

Upstream 100 bases:

>100_bases
AGGCTTCGGTAAAGGCGCTCATCGCCGAACTCGCGGCCTGAAGACCGATCCACCATCACACCTCTTGCGACTCGCGCCAC
AAGGGTGAATAGTGCAGCCA

Downstream 100 bases:

>100_bases
TACAGCCGTCGCTCGTGTGAGCAATGCCCCCAAGACAACAGGAGAGTGTCGCCGATGGATATTCGCGTTTCAGGCCACCA
GATCGAAACCGGCAGCGCGC

Product: DNA polymerase III epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MREIVFDTETTGLDPKTGDRMVEIGCVELMNRVPTGETFHAYYNPERDMPPAAEEVHGLSAAFLSDKPLFRDTADALLEF
LGDAPLVAHNAGFDFGFLNTELELIEREAISLDRMVDTVQIARKKHPGAKVSLDALCSRYGVDRSHRVKHGALLDAELLA
QVYVELLGGRQIGLGLDPEAADTDPSEAAWKPETVARAFRTPRPHAASAEELARHKVFLEGIESPLWNN

Sequences:

>Translated_229_residues
MREIVFDTETTGLDPKTGDRMVEIGCVELMNRVPTGETFHAYYNPERDMPPAAEEVHGLSAAFLSDKPLFRDTADALLEF
LGDAPLVAHNAGFDFGFLNTELELIEREAISLDRMVDTVQIARKKHPGAKVSLDALCSRYGVDRSHRVKHGALLDAELLA
QVYVELLGGRQIGLGLDPEAADTDPSEAAWKPETVARAFRTPRPHAASAEELARHKVFLEGIESPLWNN
>Mature_229_residues
MREIVFDTETTGLDPKTGDRMVEIGCVELMNRVPTGETFHAYYNPERDMPPAAEEVHGLSAAFLSDKPLFRDTADALLEF
LGDAPLVAHNAGFDFGFLNTELELIEREAISLDRMVDTVQIARKKHPGAKVSLDALCSRYGVDRSHRVKHGALLDAELLA
QVYVELLGGRQIGLGLDPEAADTDPSEAAWKPETVARAFRTPRPHAASAEELARHKVFLEGIESPLWNN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=237, Percent_Identity=39.662447257384, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25275; Mature: 25275

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVFDTETTGLDPKTGDRMVEIGCVELMNRVPTGETFHAYYNPERDMPPAAEEVHGLS
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
AAFLSDKPLFRDTADALLEFLGDAPLVAHNAGFDFGFLNTELELIEREAISLDRMVDTVQ
HHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IARKKHPGAKVSLDALCSRYGVDRSHRVKHGALLDAELLAQVYVELLGGRQIGLGLDPEA
HHHHCCCCCCEEHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
ADTDPSEAAWKPETVARAFRTPRPHAASAEELARHKVFLEGIESPLWNN
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREIVFDTETTGLDPKTGDRMVEIGCVELMNRVPTGETFHAYYNPERDMPPAAEEVHGLS
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
AAFLSDKPLFRDTADALLEFLGDAPLVAHNAGFDFGFLNTELELIEREAISLDRMVDTVQ
HHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IARKKHPGAKVSLDALCSRYGVDRSHRVKHGALLDAELLAQVYVELLGGRQIGLGLDPEA
HHHHCCCCCCEEHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
ADTDPSEAAWKPETVARAFRTPRPHAASAEELARHKVFLEGIESPLWNN
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA