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The map label for this gene is gdhB [H]

Identifier: 85375310

GI number: 85375310

Start: 2511009

End: 2512004

Strand: Direct

Name: gdhB [H]

Synonym: ELI_12415

Alternate gene names: 85375310

Gene position: 2511009-2512004 (Clockwise)

Preceding gene: 85375309

Following gene: 85375311

Centisome position: 82.26

GC content: 64.96

Gene sequence:

>996_bases
GTGTTACTGTCGTCGGCCAAGCTGGCGCTGCAGGACGCCATCGAAGCAAGCCCGCTGCCCGACGATCCGGAACTGCAGCG
CAACCTGTCGGAATATTTCCCCGCGCCGATGCGCCAGGCATACAAGAAGCAGATCGACAACCACCGGCTGCGCCGGGACA
TCATCGCCACCGACCTTGCCAACCGCATCGTCAACCGGCTGGGCCTGATCCATCCCTACGAGCTGGCGGAAGAGGAAAGC
GTGGGGCTTGCCGAAGTCGCGTCCGCATTCGTCGCTGCCGAGCGGCTGTTCGATGTGCGCGAAATCTGGGAGGAACTGGA
CGAAGCTGCAATGCCCGAAGCGACCCGGCTGATCCTGTTCGACCGCGCGGCGAGCGCGATGCGCATCCAGATGGCCGATG
TGCTGCGAATATCGAACGGCTTCCGGATGCCGAGCGACGTGGTCGACGAACTCGGCAGGGGCGTGCAGAAACTTTCAACC
GGAACCGAGAAATTGCTCGCCGACGAAAGCCTTGTGCTCACGACCAGGCTGCAGCGCGAATTCGCCAGTGCCGGTGCGCC
GGAGAAGCTCGCGGCCAAGGTCACGCACCTGTTCGATCTCGACGGAGCCGTGGGCCTCGCCGACCTTGCCAAGCGCACGG
AAATCGACCCCCGCAAGCTGACCAATGCCTTCACCATCCTCGGGCAAGATCTCGGCCTGGCCTGGGCGCAGGGGACGGCG
GCACTGATGAGCCCGTCGGACGTCTGGGAGCGCCTGCTGGTCGCAGGTCTCGCGCGCGACTTCCAGCAGATGCGGCTGGA
ATTCCTGCAGCGCCTGACGCGGCGCAAAGGGATGAAGGACAATCCGTGCGAAACGGTGAATGCCTGGCTCGACGAGAATG
CCGGGGCGATCCGGCAGTTTCGCTCGATGATCACCCGCGCACGTGCGCATACGCCGGTTGCGCCCGCCATGCTGGCGCAG
ATTGCCAGCCAGGCGCGCAACGTCCTGTCGCGCTGA

Upstream 100 bases:

>100_bases
ACTGGGCTATCTCGACCGCCGGACCGAGGGGCTTGCCGACAACGAGACGTTCAACCGCCGCGCAACCGACGGGGCGGGCT
TCACGCGGCCCGAGCTGGCG

Downstream 100 bases:

>100_bases
ACCCGAACAGGCTTGACGAGCGGGGCGCACCACCCCCATTCCGCTGCGCATGGATCGAGCGGACATTTGCATCGTGGGGG
CAGGGCACGGCGGCGCGCAG

Product: NAD-glutamate dehydrogenase

Products: NA

Alternate protein names: NAD-GDH; NAD(+)-dependent glutamate dehydrogenase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MLLSSAKLALQDAIEASPLPDDPELQRNLSEYFPAPMRQAYKKQIDNHRLRRDIIATDLANRIVNRLGLIHPYELAEEES
VGLAEVASAFVAAERLFDVREIWEELDEAAMPEATRLILFDRAASAMRIQMADVLRISNGFRMPSDVVDELGRGVQKLST
GTEKLLADESLVLTTRLQREFASAGAPEKLAAKVTHLFDLDGAVGLADLAKRTEIDPRKLTNAFTILGQDLGLAWAQGTA
ALMSPSDVWERLLVAGLARDFQQMRLEFLQRLTRRKGMKDNPCETVNAWLDENAGAIRQFRSMITRARAHTPVAPAMLAQ
IASQARNVLSR

Sequences:

>Translated_331_residues
MLLSSAKLALQDAIEASPLPDDPELQRNLSEYFPAPMRQAYKKQIDNHRLRRDIIATDLANRIVNRLGLIHPYELAEEES
VGLAEVASAFVAAERLFDVREIWEELDEAAMPEATRLILFDRAASAMRIQMADVLRISNGFRMPSDVVDELGRGVQKLST
GTEKLLADESLVLTTRLQREFASAGAPEKLAAKVTHLFDLDGAVGLADLAKRTEIDPRKLTNAFTILGQDLGLAWAQGTA
ALMSPSDVWERLLVAGLARDFQQMRLEFLQRLTRRKGMKDNPCETVNAWLDENAGAIRQFRSMITRARAHTPVAPAMLAQ
IASQARNVLSR
>Mature_331_residues
MLLSSAKLALQDAIEASPLPDDPELQRNLSEYFPAPMRQAYKKQIDNHRLRRDIIATDLANRIVNRLGLIHPYELAEEES
VGLAEVASAFVAAERLFDVREIWEELDEAAMPEATRLILFDRAASAMRIQMADVLRISNGFRMPSDVVDELGRGVQKLST
GTEKLLADESLVLTTRLQREFASAGAPEKLAAKVTHLFDLDGAVGLADLAKRTEIDPRKLTNAFTILGQDLGLAWAQGTA
ALMSPSDVWERLLVAGLARDFQQMRLEFLQRLTRRKGMKDNPCETVNAWLDENAGAIRQFRSMITRARAHTPVAPAMLAQ
IASQARNVLSR

Specific function: Involved in arginine catabolism by converting L- glutamate, into 2-oxoglutarate, which is then channeled into the tricarboxylic acid cycle. Can also utilize other amino acids of the glutamate family [H]

COG id: COG2902

COG function: function code E; NAD-specific glutamate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR007780 [H]

Pfam domain/function: PF05088 Bac_GDH [H]

EC number: =1.4.1.2 [H]

Molecular weight: Translated: 36827; Mature: 36827

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSSAKLALQDAIEASPLPDDPELQRNLSEYFPAPMRQAYKKQIDNHRLRRDIIATDLA
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NRIVNRLGLIHPYELAEEESVGLAEVASAFVAAERLFDVREIWEELDEAAMPEATRLILF
HHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DRAASAMRIQMADVLRISNGFRMPSDVVDELGRGVQKLSTGTEKLLADESLVLTTRLQRE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FASAGAPEKLAAKVTHLFDLDGAVGLADLAKRTEIDPRKLTNAFTILGQDLGLAWAQGTA
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCH
ALMSPSDVWERLLVAGLARDFQQMRLEFLQRLTRRKGMKDNPCETVNAWLDENAGAIRQF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHH
RSMITRARAHTPVAPAMLAQIASQARNVLSR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLSSAKLALQDAIEASPLPDDPELQRNLSEYFPAPMRQAYKKQIDNHRLRRDIIATDLA
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NRIVNRLGLIHPYELAEEESVGLAEVASAFVAAERLFDVREIWEELDEAAMPEATRLILF
HHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DRAASAMRIQMADVLRISNGFRMPSDVVDELGRGVQKLSTGTEKLLADESLVLTTRLQRE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FASAGAPEKLAAKVTHLFDLDGAVGLADLAKRTEIDPRKLTNAFTILGQDLGLAWAQGTA
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCH
ALMSPSDVWERLLVAGLARDFQQMRLEFLQRLTRRKGMKDNPCETVNAWLDENAGAIRQF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHH
RSMITRARAHTPVAPAMLAQIASQARNVLSR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11133942; 10984043; 9286980 [H]