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The map label for this gene is basS [H]

Identifier: 85375212

GI number: 85375212

Start: 2405325

End: 2406797

Strand: Direct

Name: basS [H]

Synonym: ELI_11925

Alternate gene names: 85375212

Gene position: 2405325-2406797 (Clockwise)

Preceding gene: 85375211

Following gene: 85375213

Centisome position: 78.8

GC content: 70.06

Gene sequence:

>1473_bases
ATGCGGCTGTGGCCCAGGAGCCTGCTCGGCCAGACATTGCTGGCGGTCGCGCTGGCGCTGCTGGTCGCGCAGGCGATTTC
CGCCGTGCTCCTTTACCAGGCGGCGGAGAACCGCCGCGAAACCGCATTGGTCAATGCCGCCGCCTTCAGCCTGCTGGTCG
ATCCCGATACGCGCGCCAACCGGATCCGCCGCGGCTTCGAAGGCAGGCGCTTCGATCGCACAGGGGATCGCGCAGGGGAT
CGCGCAGGGGATCGCGCAGGGGATCGCGCCGATCCCGGGTCGTCGTTCCGTCCGCGTCGCGGGGGTCGTTTCCGCACGCG
CACCAGCGATTCGCCTCCGCTCCTGCCCGGCGAAACCAATCTCGAAGACACCGCCGAGCGCCTGACCGATACCTTGGCGG
GCCAGGGCATCAGGCCCGTCGCCGTCCAGCTTACCCTGCGCCGGTCCGGCAGCGATCCGGTGTTGCAGCGACGCGCGCAG
CGCAATCCACGCTTCGCCGCGCGCCCGGGCTGGGCCGACAGGCAGCTGCTGGTCGCCGGCATCCAGCTGGAAGAAGGCGG
TCCGTGGCGGATCGCCCGCGTGCCGGTGCCCGAGCGCGAGCCGCGCGTCGTCGGCGGCATCGTCGCACAGACGCTGGTCA
TCTACGCGGTACTGGTCGGTGTCCTGTACCTCCTTTTGCGGCGCATCACGCATCCACTCGCCGCCCTGACCCGCCGCACG
AGCGAATTCACGCGCACGCAGGATGCCTCTTCCCCACTGGCGCCGGCCGGGCCGCAGGATATCAGCGCGCTGATCGCAGC
CCATAACGCGATGGAGGCGCGGATCGTCGCCATGCTCGACGAGAAGGACGTCATGCTCGGCGCGATCGGCCACGATCTCA
AGACCCCGCTTGCTGCCCTGCGCGTGCGGATCGAATCGGTCGAAGACGAGACCCAGCGCGCCAGGATGGCCGCGAGCATC
GAGGACCTCACCCAGTCGCTCGACGATATCCTCTCGCTCGCCCGCATCGGTCGCGCCGGCCAGCAGGCCGAACAGGCCCA
GCTCGGCGCCCTGGTCGAAGCGGTGGTCGAGGAATTCGAGGACATGGGCCAGCCGGTCACGCTCGTCGCCAGCGAGCGGA
TCGCCCATCCGGTCCATGTCACCTGGCTGCGCCGCGCGCTGCGCAACCTTATCGCCAACGCCGTGCGCTATGCCGGCACC
GTCGAGGTTTCTCTGCTGCGCGATGGCGGCACGATCATCCTACGCGTCGACGACAGCGGCCCCGGCATTCCCGCCGGCCG
AATCGACGCCATGCTCGAACCCTTCCAGCGCGGCGAAGCCAGCCGCAACCGCGCCACCGGCGGCGCCGGGCTCGGCCTCA
CCCTCGCCCGCGCCATCGCCGAGCAGCATGGCGGCGAGCTGGTGCTGGCCAATCGCGATGTGGCAAGTAACGAAACCGGT
CTGCGCGCCGAAATCAGGCTGCCCGCTGCCTGA

Upstream 100 bases:

>100_bases
AGCCGACAGCCGCAATCCGCATTTCATCCAGACCGTGCGTGGGGGCGGCTATCGCTTCGCCGCAGACGTCGCGCGCGTCG
CGCAGGCGGGGGGCTGAGCC

Downstream 100 bases:

>100_bases
CAGCGTGCCGATGGCGCGCTAGGGCTGTGCAACAGCTCCGGGAGTCTATCTTTTGCCGCACATCCTCTACGCCGCGCCGC
TTTCGCTTTATTCCGGCAAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MRLWPRSLLGQTLLAVALALLVAQAISAVLLYQAAENRRETALVNAAAFSLLVDPDTRANRIRRGFEGRRFDRTGDRAGD
RAGDRAGDRADPGSSFRPRRGGRFRTRTSDSPPLLPGETNLEDTAERLTDTLAGQGIRPVAVQLTLRRSGSDPVLQRRAQ
RNPRFAARPGWADRQLLVAGIQLEEGGPWRIARVPVPEREPRVVGGIVAQTLVIYAVLVGVLYLLLRRITHPLAALTRRT
SEFTRTQDASSPLAPAGPQDISALIAAHNAMEARIVAMLDEKDVMLGAIGHDLKTPLAALRVRIESVEDETQRARMAASI
EDLTQSLDDILSLARIGRAGQQAEQAQLGALVEAVVEEFEDMGQPVTLVASERIAHPVHVTWLRRALRNLIANAVRYAGT
VEVSLLRDGGTIILRVDDSGPGIPAGRIDAMLEPFQRGEASRNRATGGAGLGLTLARAIAEQHGGELVLANRDVASNETG
LRAEIRLPAA

Sequences:

>Translated_490_residues
MRLWPRSLLGQTLLAVALALLVAQAISAVLLYQAAENRRETALVNAAAFSLLVDPDTRANRIRRGFEGRRFDRTGDRAGD
RAGDRAGDRADPGSSFRPRRGGRFRTRTSDSPPLLPGETNLEDTAERLTDTLAGQGIRPVAVQLTLRRSGSDPVLQRRAQ
RNPRFAARPGWADRQLLVAGIQLEEGGPWRIARVPVPEREPRVVGGIVAQTLVIYAVLVGVLYLLLRRITHPLAALTRRT
SEFTRTQDASSPLAPAGPQDISALIAAHNAMEARIVAMLDEKDVMLGAIGHDLKTPLAALRVRIESVEDETQRARMAASI
EDLTQSLDDILSLARIGRAGQQAEQAQLGALVEAVVEEFEDMGQPVTLVASERIAHPVHVTWLRRALRNLIANAVRYAGT
VEVSLLRDGGTIILRVDDSGPGIPAGRIDAMLEPFQRGEASRNRATGGAGLGLTLARAIAEQHGGELVLANRDVASNETG
LRAEIRLPAA
>Mature_490_residues
MRLWPRSLLGQTLLAVALALLVAQAISAVLLYQAAENRRETALVNAAAFSLLVDPDTRANRIRRGFEGRRFDRTGDRAGD
RAGDRAGDRADPGSSFRPRRGGRFRTRTSDSPPLLPGETNLEDTAERLTDTLAGQGIRPVAVQLTLRRSGSDPVLQRRAQ
RNPRFAARPGWADRQLLVAGIQLEEGGPWRIARVPVPEREPRVVGGIVAQTLVIYAVLVGVLYLLLRRITHPLAALTRRT
SEFTRTQDASSPLAPAGPQDISALIAAHNAMEARIVAMLDEKDVMLGAIGHDLKTPLAALRVRIESVEDETQRARMAASI
EDLTQSLDDILSLARIGRAGQQAEQAQLGALVEAVVEEFEDMGQPVTLVASERIAHPVHVTWLRRALRNLIANAVRYAGT
VEVSLLRDGGTIILRVDDSGPGIPAGRIDAMLEPFQRGEASRNRATGGAGLGLTLARAIAEQHGGELVLANRDVASNETG
LRAEIRLPAA

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=28.4280936454849, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787894, Length=211, Percent_Identity=34.5971563981043, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=28.0334728033473, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789808, Length=292, Percent_Identity=27.3972602739726, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790346, Length=249, Percent_Identity=29.718875502008, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=296, Percent_Identity=26.0135135135135, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789403, Length=344, Percent_Identity=27.3255813953488, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=308, Percent_Identity=25.6493506493506, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=281, Percent_Identity=25.9786476868327, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=26.6409266409266, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52981; Mature: 52981

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLWPRSLLGQTLLAVALALLVAQAISAVLLYQAAENRRETALVNAAAFSLLVDPDTRAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCHHHH
RIRRGFEGRRFDRTGDRAGDRAGDRAGDRADPGSSFRPRRGGRFRTRTSDSPPLLPGETN
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LEDTAERLTDTLAGQGIRPVAVQLTLRRSGSDPVLQRRAQRNPRFAARPGWADRQLLVAG
HHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEE
IQLEEGGPWRIARVPVPEREPRVVGGIVAQTLVIYAVLVGVLYLLLRRITHPLAALTRRT
EEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEFTRTQDASSPLAPAGPQDISALIAAHNAMEARIVAMLDEKDVMLGAIGHDLKTPLAAL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCHHHHHHHHH
RVRIESVEDETQRARMAASIEDLTQSLDDILSLARIGRAGQQAEQAQLGALVEAVVEEFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DMGQPVTLVASERIAHPVHVTWLRRALRNLIANAVRYAGTVEVSLLRDGGTIILRVDDSG
HCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCC
PGIPAGRIDAMLEPFQRGEASRNRATGGAGLGLTLARAIAEQHGGELVLANRDVASNETG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LRAEIRLPAA
CEEEEECCCC
>Mature Secondary Structure
MRLWPRSLLGQTLLAVALALLVAQAISAVLLYQAAENRRETALVNAAAFSLLVDPDTRAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCHHHH
RIRRGFEGRRFDRTGDRAGDRAGDRAGDRADPGSSFRPRRGGRFRTRTSDSPPLLPGETN
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LEDTAERLTDTLAGQGIRPVAVQLTLRRSGSDPVLQRRAQRNPRFAARPGWADRQLLVAG
HHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEE
IQLEEGGPWRIARVPVPEREPRVVGGIVAQTLVIYAVLVGVLYLLLRRITHPLAALTRRT
EEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEFTRTQDASSPLAPAGPQDISALIAAHNAMEARIVAMLDEKDVMLGAIGHDLKTPLAAL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCHHHHHHHHH
RVRIESVEDETQRARMAASIEDLTQSLDDILSLARIGRAGQQAEQAQLGALVEAVVEEFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DMGQPVTLVASERIAHPVHVTWLRRALRNLIANAVRYAGTVEVSLLRDGGTIILRVDDSG
HCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCC
PGIPAGRIDAMLEPFQRGEASRNRATGGAGLGLTLARAIAEQHGGELVLANRDVASNETG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LRAEIRLPAA
CEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]