Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 85375211

GI number: 85375211

Start: 2404575

End: 2405321

Strand: Direct

Name: ompR [H]

Synonym: ELI_11920

Alternate gene names: 85375211

Gene position: 2404575-2405321 (Clockwise)

Preceding gene: 85375210

Following gene: 85375212

Centisome position: 78.78

GC content: 68.01

Gene sequence:

>747_bases
ATGACGGGAAACGACGCGACATCCGCCCCGGTGCACATCCTGCTGGTCGATGACGAGCCCAGCCTGCGCGAACCCCTGGC
CGAGTATCTTGCCGGCCAGGGGTTTCGCATTTCCGAGGCCGACAGCGCGGCGGGCGCGCGCTCTGTCCTGCTCAACGAAC
GCCCGGATATCGCGCTGGTCGACATCATGATGCCGGGCGAGGACGGCCTGTCGCTCACCCGCCACCTGATCGAGACGCGC
GACCTGCCCGTGATCCTGCTGACCGCCAGGGGCGAAACGACCGACCGCATTATCGGGCTGGAGATCGGCGCCGACGATTA
CGTGACCAAACCATTCGAGCCACGCGAACTGGTCGCGCGGATCCGCTCGGTCCTGCGCCGGGCCGGGCGCGCGCCCGCGG
TCGATGCGGAGGACGCTTTCTATGTCTTCGAAGGCTGGCAGCTCGATCCGCTCAAGCGTCGCCTGACCGACCCGGACGGG
GCGCTGGTGGCGATCTCGACCGCCGAATTCCGCATGCTGCGCGCCTTCCTCGATCATCCGAAGAAAGTGCTCGATCGCGA
TCGCCTGCTCGACCTTGTGCAGGGCCGCGAGGCGCACCTCTTCGACCGTGCGGTCGACAACCAGGTCAGCCGCCTGCGCC
GCAAGATCGAAGCCGACAGCCGCAATCCGCATTTCATCCAGACCGTGCGTGGGGGCGGCTATCGCTTCGCCGCAGACGTC
GCGCGCGTCGCGCAGGCGGGGGGCTGA

Upstream 100 bases:

>100_bases
GCCGACGGCGACGGCACGATCACCCGCGACGAACGCCGCGCCGCGCGGCAGGCCATGCGCGCCCAGCGTCGCGGCCAGTA
AGAACGCGGAGCCGGGGCGA

Downstream 100 bases:

>100_bases
GCCATGCGGCTGTGGCCCAGGAGCCTGCTCGGCCAGACATTGCTGGCGGTCGCGCTGGCGCTGCTGGTCGCGCAGGCGAT
TTCCGCCGTGCTCCTTTACC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTGNDATSAPVHILLVDDEPSLREPLAEYLAGQGFRISEADSAAGARSVLLNERPDIALVDIMMPGEDGLSLTRHLIETR
DLPVILLTARGETTDRIIGLEIGADDYVTKPFEPRELVARIRSVLRRAGRAPAVDAEDAFYVFEGWQLDPLKRRLTDPDG
ALVAISTAEFRMLRAFLDHPKKVLDRDRLLDLVQGREAHLFDRAVDNQVSRLRRKIEADSRNPHFIQTVRGGGYRFAADV
ARVAQAGG

Sequences:

>Translated_248_residues
MTGNDATSAPVHILLVDDEPSLREPLAEYLAGQGFRISEADSAAGARSVLLNERPDIALVDIMMPGEDGLSLTRHLIETR
DLPVILLTARGETTDRIIGLEIGADDYVTKPFEPRELVARIRSVLRRAGRAPAVDAEDAFYVFEGWQLDPLKRRLTDPDG
ALVAISTAEFRMLRAFLDHPKKVLDRDRLLDLVQGREAHLFDRAVDNQVSRLRRKIEADSRNPHFIQTVRGGGYRFAADV
ARVAQAGG
>Mature_247_residues
TGNDATSAPVHILLVDDEPSLREPLAEYLAGQGFRISEADSAAGARSVLLNERPDIALVDIMMPGEDGLSLTRHLIETRD
LPVILLTARGETTDRIIGLEIGADDYVTKPFEPRELVARIRSVLRRAGRAPAVDAEDAFYVFEGWQLDPLKRRLTDPDGA
LVAISTAEFRMLRAFLDHPKKVLDRDRLLDLVQGREAHLFDRAVDNQVSRLRRKIEADSRNPHFIQTVRGGGYRFAADVA
RVAQAGG

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=44.7826086956522, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=41.9213973799127, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=38.7931034482759, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=40.8510638297872, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=36.1702127659575, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=38.9380530973451, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=31.3304721030043, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=35.1111111111111, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=34.3478260869565, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=28.9473684210526, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=28.8888888888889, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=30.2631578947368, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=41.1214953271028, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788905, Length=130, Percent_Identity=33.0769230769231, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27487; Mature: 27355

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNDATSAPVHILLVDDEPSLREPLAEYLAGQGFRISEADSAAGARSVLLNERPDIALV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEECCCCCCCCHHHHHCCCCCCEEEE
DIMMPGEDGLSLTRHLIETRDLPVILLTARGETTDRIIGLEIGADDYVTKPFEPRELVAR
EEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHH
IRSVLRRAGRAPAVDAEDAFYVFEGWQLDPLKRRLTDPDGALVAISTAEFRMLRAFLDHP
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCH
KKVLDRDRLLDLVQGREAHLFDRAVDNQVSRLRRKIEADSRNPHFIQTVRGGGYRFAADV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHH
ARVAQAGG
HHHHHCCC
>Mature Secondary Structure 
TGNDATSAPVHILLVDDEPSLREPLAEYLAGQGFRISEADSAAGARSVLLNERPDIALV
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEECCCCCCCCHHHHHCCCCCCEEEE
DIMMPGEDGLSLTRHLIETRDLPVILLTARGETTDRIIGLEIGADDYVTKPFEPRELVAR
EEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHH
IRSVLRRAGRAPAVDAEDAFYVFEGWQLDPLKRRLTDPDGALVAISTAEFRMLRAFLDHP
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCH
KKVLDRDRLLDLVQGREAHLFDRAVDNQVSRLRRKIEADSRNPHFIQTVRGGGYRFAADV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHH
ARVAQAGG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]