Click here to switch to the map view.

The map label for this gene is lgt

Identifier: 85375190

GI number: 85375190

Start: 2378866

End: 2379711

Strand: Reverse

Name: lgt

Synonym: ELI_11815

Alternate gene names: 85375190

Gene position: 2379711-2378866 (Counterclockwise)

Preceding gene: 85375194

Following gene: 85375189

Centisome position: 77.96

GC content: 63.36

Gene sequence:

>846_bases
TTGGCCGACGCTGCTTCGCAGCCGATCTACTGGTCCGAGCTCGGCCTGTCGCCGGGGATCGATCTCGGCTTTTTCACGCT
GCGCTTTTATTCGCTCGCCTATATAGTCGGTATCGTCCTCGCCTATTGGCACCTCGGCAAGATGATCAAGGCACCCGGCG
CGCCCATGGCGCAGAGCCATGCCGACGACCTGTTCTTCTATTGCACGCTCGGCGTCATTTTCGGCGGCAGGATCGGCTAT
GTGCTGTTCTACCGCCCGGATCTGCTCGGCACGCTGGACATGTTCAAGGTGTGGGAAGGCGGCATGAGCTTTCACGGCGG
GGTGATCGGCGTGGTGCTGGCGATCCTGTTCGTGTCGTGGCGCGGCAAGCTCAACTGGCTGCGCGTGTGCGATTACATCG
CCGTCAACGTGCCTTTCGGCATGTTCCTCGGGCGGATGGCGAATTTCGTGAACGGCGAATTGTACGGCCGCCCGACCGAT
GTCAGCTGGGCGATGATTTTCCCGACCGATCCCGATCAGGTCGCACGGCATCCGAGCCAGCTTTACCAGGCCGGGCTGGA
AGGCCTGCTGATGATGGCGGTGATGCTGCTGTTGTTCTGGCAGACCAGAGCGCGGTGGAGGCCCGGCGTGCTGGTCGGTG
TCTTCACCATCGGCATCGCCGGCGCGCGCTTCGTCAACGAATTCTTCCGCGCACCCGACGCGCATCTTGCCGATGTCGTC
CGCGACACCGGGTTGAGCCAGGGCCAGTGGCTCTCGATCCCGATGATCCTCGTCGGGCTGGCGGTGGTGGTCTATGCGCT
GACCCGCAAGACCAAGGGCACGCCCGAGAAGCCAGCCTCGGCGTGA

Upstream 100 bases:

>100_bases
TTTCGTCGAAACCCGGGCTGTGCCAAAGCCGTGCCGAAAGAAGGGCCGTGTCCTCGTTGTCTCGCGCCCCATGTAAGAGG
TCTTGTCCGTGCTGTCACTA

Downstream 100 bases:

>100_bases
GGGGGCGATGGCCGAAACGCTCGCAGAGATCTTCCGCCGCCTGATCCGCAACACCGGGCCGATCTCGGTCAGCCAGTTCA
TGGGCGAAAGCAACGCGCGC

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MADAASQPIYWSELGLSPGIDLGFFTLRFYSLAYIVGIVLAYWHLGKMIKAPGAPMAQSHADDLFFYCTLGVIFGGRIGY
VLFYRPDLLGTLDMFKVWEGGMSFHGGVIGVVLAILFVSWRGKLNWLRVCDYIAVNVPFGMFLGRMANFVNGELYGRPTD
VSWAMIFPTDPDQVARHPSQLYQAGLEGLLMMAVMLLLFWQTRARWRPGVLVGVFTIGIAGARFVNEFFRAPDAHLADVV
RDTGLSQGQWLSIPMILVGLAVVVYALTRKTKGTPEKPASA

Sequences:

>Translated_281_residues
MADAASQPIYWSELGLSPGIDLGFFTLRFYSLAYIVGIVLAYWHLGKMIKAPGAPMAQSHADDLFFYCTLGVIFGGRIGY
VLFYRPDLLGTLDMFKVWEGGMSFHGGVIGVVLAILFVSWRGKLNWLRVCDYIAVNVPFGMFLGRMANFVNGELYGRPTD
VSWAMIFPTDPDQVARHPSQLYQAGLEGLLMMAVMLLLFWQTRARWRPGVLVGVFTIGIAGARFVNEFFRAPDAHLADVV
RDTGLSQGQWLSIPMILVGLAVVVYALTRKTKGTPEKPASA
>Mature_280_residues
ADAASQPIYWSELGLSPGIDLGFFTLRFYSLAYIVGIVLAYWHLGKMIKAPGAPMAQSHADDLFFYCTLGVIFGGRIGYV
LFYRPDLLGTLDMFKVWEGGMSFHGGVIGVVLAILFVSWRGKLNWLRVCDYIAVNVPFGMFLGRMANFVNGELYGRPTDV
SWAMIFPTDPDQVARHPSQLYQAGLEGLLMMAVMLLLFWQTRARWRPGVLVGVFTIGIAGARFVNEFFRAPDAHLADVVR
DTGLSQGQWLSIPMILVGLAVVVYALTRKTKGTPEKPASA

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=275, Percent_Identity=37.8181818181818, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_ERYLH (Q2N786)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459252.1
- STRING:   Q2N786
- GeneID:   3870297
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_11815
- NMPDR:   fig|314225.3.peg.662
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   NPIAFSL
- PhylomeDB:   Q2N786
- ProtClustDB:   PRK00052
- BioCyc:   ELIT314225:ELI_11815-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 31098; Mature: 30967

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe12d0e0)-; HASH(0x43ea0994)-; HASH(0xe17e97c)-; HASH(0x43ea0868)-; HASH(0x43e3c23c)-; HASH(0x43ea0d3c)-; HASH(0x43ea09e8)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAASQPIYWSELGLSPGIDLGFFTLRFYSLAYIVGIVLAYWHLGKMIKAPGAPMAQSH
CCCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ADDLFFYCTLGVIFGGRIGYVLFYRPDLLGTLDMFKVWEGGMSFHGGVIGVVLAILFVSW
HHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RGKLNWLRVCDYIAVNVPFGMFLGRMANFVNGELYGRPTDVSWAMIFPTDPDQVARHPSQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCCHHH
LYQAGLEGLLMMAVMLLLFWQTRARWRPGVLVGVFTIGIAGARFVNEFFRAPDAHLADVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RDTGLSQGQWLSIPMILVGLAVVVYALTRKTKGTPEKPASA
HHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
ADAASQPIYWSELGLSPGIDLGFFTLRFYSLAYIVGIVLAYWHLGKMIKAPGAPMAQSH
CCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ADDLFFYCTLGVIFGGRIGYVLFYRPDLLGTLDMFKVWEGGMSFHGGVIGVVLAILFVSW
HHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RGKLNWLRVCDYIAVNVPFGMFLGRMANFVNGELYGRPTDVSWAMIFPTDPDQVARHPSQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCCHHH
LYQAGLEGLLMMAVMLLLFWQTRARWRPGVLVGVFTIGIAGARFVNEFFRAPDAHLADVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RDTGLSQGQWLSIPMILVGLAVVVYALTRKTKGTPEKPASA
HHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA