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The map label for this gene is exoB [H]

Identifier: 85375013

GI number: 85375013

Start: 2211086

End: 2212099

Strand: Reverse

Name: exoB [H]

Synonym: ELI_10930

Alternate gene names: 85375013

Gene position: 2212099-2211086 (Counterclockwise)

Preceding gene: 85375017

Following gene: 85375012

Centisome position: 72.47

GC content: 62.62

Gene sequence:

>1014_bases
ATGACCGACCCCAAGGAAATTCCTGTCCTCGTCACCGGCGGCGCCGGGTATATCGGCAGCCACGCCGTGCTGGCGCTCCG
CGACGCGGGACGCAAGGTTGCAGTGATCGACAACCTCACCACCGGCTTTCGCTTCGCCGTGCCCGAAGATGTGCCGTTCT
ACCAAGGCGATATCCAGGATGCGGAGCTTTTGGCCAACATCTTCGCCGAAGAGAAGATTGGCGCGGTCATGCATTTTGCC
GGGTCCATAGTCGTCCCGGACTCGGTCGAGGACCCGCTTGGCTATTATCACAACAATACGGTCAAGAGCCGCGCGCTGAT
AGAGGCTGCGGTCAAGGCCGGGGTGAGGCACTTCATCTTCAGCTCGACCGCTGCGACCTATGGCGTGCCGAACGTGTCGC
CTGTTACCGAGGACACGCCCAAGCAGCCGATCAACCCCTATGGCTGGTCCAAGCTTATGACCGAGCAGATGCTGGCAGAT
ACCGCCTTTGCCCATGCGATCAACTATTGCACCCTGCGCTATTTCAACGTCGCGGGCGCCGACCCTCAGGCGCGCACCGG
GCAATCGACGGCAGGCGCAACACATCTGATCAAGGTCGCGGTCGAAGCGGCGCTGGGCAAGCGTGACAGCGTGGCGGTGT
TCGGGACCGATTACGACACGCCCGACGGCACCGGCGTGCGCGATTATATCCATGTCAGCGACCTGGCGGCTGCGCATCTG
CACGCGCTCGATGCCTTGATCGAGCAGCCGAAGCGCTCGCTCACCATGAATTGCGGCTATGGGCGCGGATTCTCCGTGCT
CGAAGTCCTCGACGCGGTCGACCGGGTGACCAACAAGGCGATCGAGCGCGTCATGTCGCCGCGCCGTGCGGGCGATCCGG
CCTCGCTGATTTCCGATCCTACGCGTATTCGCGCCACCGTGCCGTGGCAGCCGCAATATGACGATCTCGACACGATCATC
GACCATGCGCTGCAATGGGAGCGCAAGCTCACCGACCTGCGCACAGAAGGTTGA

Upstream 100 bases:

>100_bases
TAGCGCAGCGTCGCAACGTCGGCCAGTGCCTCGCGATTTGCTGGCGAAAGCTTTGCTGTCGTTAACCACATTCTTCGGCA
TTGCTGATACAGGCCGAGGC

Downstream 100 bases:

>100_bases
CGACAGGCGATTCTCGCCCTACCTGCGCCACAGATTTCCGGCATCGGAGCTGTTCTCCGGTGCCTTTTCATTTCAGGATC
AGATCGATGAAAGTCCGCAA

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTDPKEIPVLVTGGAGYIGSHAVLALRDAGRKVAVIDNLTTGFRFAVPEDVPFYQGDIQDAELLANIFAEEKIGAVMHFA
GSIVVPDSVEDPLGYYHNNTVKSRALIEAAVKAGVRHFIFSSTAATYGVPNVSPVTEDTPKQPINPYGWSKLMTEQMLAD
TAFAHAINYCTLRYFNVAGADPQARTGQSTAGATHLIKVAVEAALGKRDSVAVFGTDYDTPDGTGVRDYIHVSDLAAAHL
HALDALIEQPKRSLTMNCGYGRGFSVLEVLDAVDRVTNKAIERVMSPRRAGDPASLISDPTRIRATVPWQPQYDDLDTII
DHALQWERKLTDLRTEG

Sequences:

>Translated_337_residues
MTDPKEIPVLVTGGAGYIGSHAVLALRDAGRKVAVIDNLTTGFRFAVPEDVPFYQGDIQDAELLANIFAEEKIGAVMHFA
GSIVVPDSVEDPLGYYHNNTVKSRALIEAAVKAGVRHFIFSSTAATYGVPNVSPVTEDTPKQPINPYGWSKLMTEQMLAD
TAFAHAINYCTLRYFNVAGADPQARTGQSTAGATHLIKVAVEAALGKRDSVAVFGTDYDTPDGTGVRDYIHVSDLAAAHL
HALDALIEQPKRSLTMNCGYGRGFSVLEVLDAVDRVTNKAIERVMSPRRAGDPASLISDPTRIRATVPWQPQYDDLDTII
DHALQWERKLTDLRTEG
>Mature_336_residues
TDPKEIPVLVTGGAGYIGSHAVLALRDAGRKVAVIDNLTTGFRFAVPEDVPFYQGDIQDAELLANIFAEEKIGAVMHFAG
SIVVPDSVEDPLGYYHNNTVKSRALIEAAVKAGVRHFIFSSTAATYGVPNVSPVTEDTPKQPINPYGWSKLMTEQMLADT
AFAHAINYCTLRYFNVAGADPQARTGQSTAGATHLIKVAVEAALGKRDSVAVFGTDYDTPDGTGVRDYIHVSDLAAAHLH
ALDALIEQPKRSLTMNCGYGRGFSVLEVLDAVDRVTNKAIERVMSPRRAGDPASLISDPTRIRATVPWQPQYDDLDTIID
HALQWERKLTDLRTEG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=39.1691394658754, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=39.1691394658754, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=39.1691394658754, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI7657641, Length=248, Percent_Identity=27.8225806451613, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI42516563, Length=326, Percent_Identity=22.3926380368098, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=39.2749244712991, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1790049, Length=303, Percent_Identity=28.7128712871287, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994969, Length=361, Percent_Identity=25.7617728531856, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788353, Length=359, Percent_Identity=25.6267409470752, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=36.8731563421829, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=36.0703812316716, Blast_Score=203, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6319493, Length=330, Percent_Identity=37.5757575757576, Blast_Score=215, Evalue=9e-57,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=37.5739644970414, Blast_Score=217, Evalue=7e-57,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=23.6245954692557, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36551; Mature: 36419

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPKEIPVLVTGGAGYIGSHAVLALRDAGRKVAVIDNLTTGFRFAVPEDVPFYQGDIQD
CCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCCCH
AELLANIFAEEKIGAVMHFAGSIVVPDSVEDPLGYYHNNTVKSRALIEAAVKAGVRHFIF
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SSTAATYGVPNVSPVTEDTPKQPINPYGWSKLMTEQMLADTAFAHAINYCTLRYFNVAGA
HCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
DPQARTGQSTAGATHLIKVAVEAALGKRDSVAVFGTDYDTPDGTGVRDYIHVSDLAAAHL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
HALDALIEQPKRSLTMNCGYGRGFSVLEVLDAVDRVTNKAIERVMSPRRAGDPASLISDP
HHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
TRIRATVPWQPQYDDLDTIIDHALQWERKLTDLRTEG
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDPKEIPVLVTGGAGYIGSHAVLALRDAGRKVAVIDNLTTGFRFAVPEDVPFYQGDIQD
CCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCCCH
AELLANIFAEEKIGAVMHFAGSIVVPDSVEDPLGYYHNNTVKSRALIEAAVKAGVRHFIF
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SSTAATYGVPNVSPVTEDTPKQPINPYGWSKLMTEQMLADTAFAHAINYCTLRYFNVAGA
HCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
DPQARTGQSTAGATHLIKVAVEAALGKRDSVAVFGTDYDTPDGTGVRDYIHVSDLAAAHL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
HALDALIEQPKRSLTMNCGYGRGFSVLEVLDAVDRVTNKAIERVMSPRRAGDPASLISDP
HHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
TRIRATVPWQPQYDDLDTIIDHALQWERKLTDLRTEG
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]