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The map label for this gene is cdd [H]

Identifier: 85375017

GI number: 85375017

Start: 2214972

End: 2215394

Strand: Reverse

Name: cdd [H]

Synonym: ELI_10950

Alternate gene names: 85375017

Gene position: 2215394-2214972 (Counterclockwise)

Preceding gene: 85375018

Following gene: 85375013

Centisome position: 72.58

GC content: 65.01

Gene sequence:

>423_bases
ATGTCCGACCAAGACGAAGCACTGGCGAATGCCGCCCGCGAAGCGGCTACGCGCTCCTATTCGCCCTATTCCAATTATGC
CGTCGGCGCCGCGCTGCGATTTTCGGATGGGTCGGTCGTCACCGGCACCAATATCGAAAATGCGAGCTATGGCTTGGCGC
TGTGTGCGGAGACGGTCGCGGTTTCGAAGGCGATGGCAGACGGTATGCGCGGCGGGCTGGAAGCGGTTGCGGTCGTGGGC
CCGGCAGACAAGGGGAATGGCGCGCCGATCACACCGTGCGGGCGGTGCCGACAGGTGCTCAAGGAGCTGGCGCAACTGGG
CGGGACCGATCCCGAAATCCTCTGTGTCGGCAATGACGAAGTCCGCAAGCTGAGGCTGAGCCGGCTTTTGCCCGATGCCT
TCGGCCCGGCGGCGCTGGACTAG

Upstream 100 bases:

>100_bases
GAGGGGCGAGACCTTTTCCATGACATTGCCGTTTGACCATGGATTGCCACGCCGCCTGCGGCGGCTCGCAATGACGGATT
GGTGGAGTTAGGGTATAATT

Downstream 100 bases:

>100_bases
CCCAAAGCGATCAGTTGGAGCTTTCCGGCACCATGCAGATATCTGCCGCCAGCGGGCGGTGGTCCGAACCGACATCATCG
AGCACGGCGAAATTGCGCAC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MSDQDEALANAAREAATRSYSPYSNYAVGAALRFSDGSVVTGTNIENASYGLALCAETVAVSKAMADGMRGGLEAVAVVG
PADKGNGAPITPCGRCRQVLKELAQLGGTDPEILCVGNDEVRKLRLSRLLPDAFGPAALD

Sequences:

>Translated_140_residues
MSDQDEALANAAREAATRSYSPYSNYAVGAALRFSDGSVVTGTNIENASYGLALCAETVAVSKAMADGMRGGLEAVAVVG
PADKGNGAPITPCGRCRQVLKELAQLGGTDPEILCVGNDEVRKLRLSRLLPDAFGPAALD
>Mature_139_residues
SDQDEALANAAREAATRSYSPYSNYAVGAALRFSDGSVVTGTNIENASYGLALCAETVAVSKAMADGMRGGLEAVAVVGP
ADKGNGAPITPCGRCRQVLKELAQLGGTDPEILCVGNDEVRKLRLSRLLPDAFGPAALD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=135, Percent_Identity=36.2962962962963, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=136, Percent_Identity=38.9705882352941, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=144, Percent_Identity=36.1111111111111, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323274, Length=139, Percent_Identity=35.2517985611511, Blast_Score=87, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24582741, Length=131, Percent_Identity=45.0381679389313, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920920, Length=101, Percent_Identity=40.5940594059406, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582744, Length=98, Percent_Identity=39.7959183673469, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14402; Mature: 14271

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQDEALANAAREAATRSYSPYSNYAVGAALRFSDGSVVTGTNIENASYGLALCAETVA
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHH
VSKAMADGMRGGLEAVAVVGPADKGNGAPITPCGRCRQVLKELAQLGGTDPEILCVGNDE
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHH
VRKLRLSRLLPDAFGPAALD
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDQDEALANAAREAATRSYSPYSNYAVGAALRFSDGSVVTGTNIENASYGLALCAETVA
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHH
VSKAMADGMRGGLEAVAVVGPADKGNGAPITPCGRCRQVLKELAQLGGTDPEILCVGNDE
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHH
VRKLRLSRLLPDAFGPAALD
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]