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The map label for this gene is sucD [H]

Identifier: 85374425

GI number: 85374425

Start: 1655465

End: 1656355

Strand: Direct

Name: sucD [H]

Synonym: ELI_07990

Alternate gene names: 85374425

Gene position: 1655465-1656355 (Clockwise)

Preceding gene: 85374424

Following gene: 85374426

Centisome position: 54.23

GC content: 66.67

Gene sequence:

>891_bases
ATGTCCATCCTCGTAAACAAAGACACCAAGGTCATCACCCAGGGGATGACCGGCAACACGGGCACCTTCCACACGCAGCA
GGCGCTCGATTACGGGACGCAGATGGTCGCGGGTGTGACCCCCGGTAAGGGCGGCACCGAGCATATCGGCCTGCCGCAAT
TCGACACCGTGCGCGAGGCCAAGGACGCGACCGGCGCGACCGCGAGCTGCATCTATGTCCCGCCACCCTTCGCCGCCGAT
GCGATCTGCGAAGCGATCGATGCCGGGATCGAGCTGATCATCTGCATCACCGAGGGCATTCCGGTGCTCGACATGGTCCG
CGCCAAGCGCGCGCTGCAGGGCTCCAACTCGCGGCTGATCGGCCCCAACTGCCCCGGCGTGCTGACGCCGGACGAGTGCA
AGATCGGCATCATGCCGGGTTCCATCTTCAAGAAGGGCAGCGTCGGCGTCGTCTCGCGCTCGGGCACATTGACCTATGAA
GCCGTGCACCAGACCACCATGGTCGGCCTCGGCCAGTCGACCGCGGTCGGCATCGGCGGCGACCCGGTCAACGGCACCAA
CTTCATCGACGTGCTCGACCTGTTCCTCGACGATCCCGAGACCAAGAGCATGATCATGATCGGCGAGATCGGCGGCAGCG
CCGAAGAAGAAGCCGCTGCCTTCCTCAAGGCCGAGGCGGCCAAGGGCCGCAGCAAGCCGACGGTCGGCTTCATCGCCGGC
CGCACCGCCCCTCCGGGCCGCCGCATGGGTCACGCCGGTGCGATCGTCTCCGGCGGCAAAGGCGGCGCGGACGACAAGAT
CGCCGCGATGGAAGACGCGGGCATCCGCGTCAGCCCCTCGCCAAGCGAACTCGGCACGACGCTCGACGCGATGCTGAAGG
AAATGGCGTGA

Upstream 100 bases:

>100_bases
GCCCTTATGAGCTTCACCAAACCAGACGTGACCGATCAAACCCGCGTGATCATCGTTATCACCTCAAACAACGCATCCGC
AGCTCCATAGGGGAAACCAT

Downstream 100 bases:

>100_bases
TCGCCAAGGCCCTCTATATGAGTCCCAGCGCAGGCTGGGACCTCCCTCAATCTGGCGCGAGCCCGATGGAGGCTCCAGCC
TGCGCTGGAGCTCACGGCTA

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSILVNKDTKVITQGMTGNTGTFHTQQALDYGTQMVAGVTPGKGGTEHIGLPQFDTVREAKDATGATASCIYVPPPFAAD
AICEAIDAGIELIICITEGIPVLDMVRAKRALQGSNSRLIGPNCPGVLTPDECKIGIMPGSIFKKGSVGVVSRSGTLTYE
AVHQTTMVGLGQSTAVGIGGDPVNGTNFIDVLDLFLDDPETKSMIMIGEIGGSAEEEAAAFLKAEAAKGRSKPTVGFIAG
RTAPPGRRMGHAGAIVSGGKGGADDKIAAMEDAGIRVSPSPSELGTTLDAMLKEMA

Sequences:

>Translated_296_residues
MSILVNKDTKVITQGMTGNTGTFHTQQALDYGTQMVAGVTPGKGGTEHIGLPQFDTVREAKDATGATASCIYVPPPFAAD
AICEAIDAGIELIICITEGIPVLDMVRAKRALQGSNSRLIGPNCPGVLTPDECKIGIMPGSIFKKGSVGVVSRSGTLTYE
AVHQTTMVGLGQSTAVGIGGDPVNGTNFIDVLDLFLDDPETKSMIMIGEIGGSAEEEAAAFLKAEAAKGRSKPTVGFIAG
RTAPPGRRMGHAGAIVSGGKGGADDKIAAMEDAGIRVSPSPSELGTTLDAMLKEMA
>Mature_295_residues
SILVNKDTKVITQGMTGNTGTFHTQQALDYGTQMVAGVTPGKGGTEHIGLPQFDTVREAKDATGATASCIYVPPPFAADA
ICEAIDAGIELIICITEGIPVLDMVRAKRALQGSNSRLIGPNCPGVLTPDECKIGIMPGSIFKKGSVGVVSRSGTLTYEA
VHQTTMVGLGQSTAVGIGGDPVNGTNFIDVLDLFLDDPETKSMIMIGEIGGSAEEEAAAFLKAEAAKGRSKPTVGFIAGR
TAPPGRRMGHAGAIVSGGKGGADDKIAAMEDAGIRVSPSPSELGTTLDAMLKEMA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=67.9442508710801, Blast_Score=342, Evalue=2e-94,
Organism=Homo sapiens, GI38569423, Length=322, Percent_Identity=29.1925465838509, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI38569421, Length=322, Percent_Identity=29.1925465838509, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=65.5290102389078, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=64.2361111111111, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=61.6438356164384, Blast_Score=350, Evalue=6e-97,
Organism=Caenorhabditis elegans, GI17557344, Length=320, Percent_Identity=25.9375, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=324, Percent_Identity=26.5432098765432, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=293, Percent_Identity=53.2423208191126, Blast_Score=283, Evalue=2e-77,
Organism=Drosophila melanogaster, GI21356559, Length=295, Percent_Identity=60.6779661016949, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI28574296, Length=295, Percent_Identity=63.0508474576271, Blast_Score=347, Evalue=4e-96,
Organism=Drosophila melanogaster, GI281363477, Length=220, Percent_Identity=31.3636363636364, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363475, Length=220, Percent_Identity=31.3636363636364, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363473, Length=220, Percent_Identity=31.3636363636364, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30348; Mature: 30217

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVNKDTKVITQGMTGNTGTFHTQQALDYGTQMVAGVTPGKGGTEHIGLPQFDTVREA
CEEEECCCCEEEEECCCCCCCCEEHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHH
KDATGATASCIYVPPPFAADAICEAIDAGIELIICITEGIPVLDMVRAKRALQGSNSRLI
HCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVLTPDECKIGIMPGSIFKKGSVGVVSRSGTLTYEAVHQTTMVGLGQSTAVGIGG
CCCCCCCCCCCCCEEEECCCHHCCCCCCEEEECCCCEEEHHHHHHHHEECCCCEEEECCC
DPVNGTNFIDVLDLFLDDPETKSMIMIGEIGGSAEEEAAAFLKAEAAKGRSKPTVGFIAG
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
RTAPPGRRMGHAGAIVSGGKGGADDKIAAMEDAGIRVSPSPSELGTTLDAMLKEMA
CCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILVNKDTKVITQGMTGNTGTFHTQQALDYGTQMVAGVTPGKGGTEHIGLPQFDTVREA
EEEECCCCEEEEECCCCCCCCEEHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHH
KDATGATASCIYVPPPFAADAICEAIDAGIELIICITEGIPVLDMVRAKRALQGSNSRLI
HCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVLTPDECKIGIMPGSIFKKGSVGVVSRSGTLTYEAVHQTTMVGLGQSTAVGIGG
CCCCCCCCCCCCCEEEECCCHHCCCCCCEEEECCCCEEEHHHHHHHHEECCCCEEEECCC
DPVNGTNFIDVLDLFLDDPETKSMIMIGEIGGSAEEEAAAFLKAEAAKGRSKPTVGFIAG
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
RTAPPGRRMGHAGAIVSGGKGGADDKIAAMEDAGIRVSPSPSELGTTLDAMLKEMA
CCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]