Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 85374295

GI number: 85374295

Start: 1525528

End: 1526466

Strand: Reverse

Name: fabD [H]

Synonym: ELI_07340

Alternate gene names: 85374295

Gene position: 1526466-1525528 (Counterclockwise)

Preceding gene: 85374296

Following gene: 85374294

Centisome position: 50.01

GC content: 65.18

Gene sequence:

>939_bases
ATGCGCGCATTTATCTTTCCCGGACAGGGCAGCCAGAAGGTCGGTATGGGCGCGGACCTGGCCGATGCCAGCGCGGCGGC
GCGCGCAGTGTTCGAGGAAGTCGACGACGCGCTCAGCCAGACTCTCAGCGATATCATGCGCGACGGGCCGGAAGCCGACC
TTACGCTGACCGAGAACGCGCAACCGGCGATCATGGCCAATGCCATCGCCACCCTGCGCGTGCTGGAGCAGGATCTCGGC
GTGTCGCTGGTCGAGACAGGCGATTGCGTCGCCGGGCATTCGCTCGGCGAGTACACTGCCCTTTGCGCGGTCGGCGCATT
CTCGCTCGCCGATACGGCGCGGCTTCTCAAGCTGCGGGGGCAGGCGATGCAGGCCGCTGTTCCGGTTGGCGAAGGAGCGA
TGGCGGCTTTGCTCGGTGCCGATATCGAGAAAGCCACAGCGCTGGCCGAGGCCGCCGCGCAGGGTGAAGTCTGCGAAATC
GCCAATGACAACGATCCGACGCAGGTCGTCATCTCCGGCCACACGGGTGCCATCGAGCGCGCGGTGGCGCTGGTGAAAGA
ACACGGCATCAAGCGCGGTGTCCCGCTGCCGGTTTCCGCGCCGTTCCACTGTTCGCTGATGCAACCTGCCGCCGATGCCA
TGGCCGAAGCGCTCGCCGAAACGCCGCCGAGCAGTTTCAGCCTGCCCGTCTATGCCAATGTCACCGCCGCCAAGGTCAGC
GACCCTGCCGAAGAGCGCGACCTGCTGGTCCAGCAGGTCACAGGCCGCGTTCGCTGGCGCGAGAGCGTGCTGGCAATGCG
CGATAGCGGGGTTGCGCACTTCATCGAACTGGGTGGCAAGGTCCTCGGTCCGATGGTGGGTCGTATCGACAAGGAAGCGC
AAATTACCAGCGCAATCACGATGGAAGATCTGGAAGCGCTCGCAAAGGAGATTGGCTGA

Upstream 100 bases:

>100_bases
GGCCCGCATCGGCCACACGGCGGACAACCACGTCGTGCCGTTCGGGGTTGCGAGTCCGCCGCAGGCTCCGTAATCGCGTC
TCCAGGACAGGAGATTTCAC

Downstream 100 bases:

>100_bases
TGTTTTCGCTCGAAGGAATGACCGCACTTGTGACCGGGGCCAGCGGCGGGATCGGCTCCTCGATCGCGCGCTCGCTGGCG
CGGCAGGGCGCACGGCTGGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRAFIFPGQGSQKVGMGADLADASAAARAVFEEVDDALSQTLSDIMRDGPEADLTLTENAQPAIMANAIATLRVLEQDLG
VSLVETGDCVAGHSLGEYTALCAVGAFSLADTARLLKLRGQAMQAAVPVGEGAMAALLGADIEKATALAEAAAQGEVCEI
ANDNDPTQVVISGHTGAIERAVALVKEHGIKRGVPLPVSAPFHCSLMQPAADAMAEALAETPPSSFSLPVYANVTAAKVS
DPAEERDLLVQQVTGRVRWRESVLAMRDSGVAHFIELGGKVLGPMVGRIDKEAQITSAITMEDLEALAKEIG

Sequences:

>Translated_312_residues
MRAFIFPGQGSQKVGMGADLADASAAARAVFEEVDDALSQTLSDIMRDGPEADLTLTENAQPAIMANAIATLRVLEQDLG
VSLVETGDCVAGHSLGEYTALCAVGAFSLADTARLLKLRGQAMQAAVPVGEGAMAALLGADIEKATALAEAAAQGEVCEI
ANDNDPTQVVISGHTGAIERAVALVKEHGIKRGVPLPVSAPFHCSLMQPAADAMAEALAETPPSSFSLPVYANVTAAKVS
DPAEERDLLVQQVTGRVRWRESVLAMRDSGVAHFIELGGKVLGPMVGRIDKEAQITSAITMEDLEALAKEIG
>Mature_312_residues
MRAFIFPGQGSQKVGMGADLADASAAARAVFEEVDDALSQTLSDIMRDGPEADLTLTENAQPAIMANAIATLRVLEQDLG
VSLVETGDCVAGHSLGEYTALCAVGAFSLADTARLLKLRGQAMQAAVPVGEGAMAALLGADIEKATALAEAAAQGEVCEI
ANDNDPTQVVISGHTGAIERAVALVKEHGIKRGVPLPVSAPFHCSLMQPAADAMAEALAETPPSSFSLPVYANVTAAKVS
DPAEERDLLVQQVTGRVRWRESVLAMRDSGVAHFIELGGKVLGPMVGRIDKEAQITSAITMEDLEALAKEIG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=30.6930693069307, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=44.0972222222222, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71984332, Length=287, Percent_Identity=28.9198606271777, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=27.4834437086093, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24665753, Length=281, Percent_Identity=34.5195729537367, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32369; Mature: 32369

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFIFPGQGSQKVGMGADLADASAAARAVFEEVDDALSQTLSDIMRDGPEADLTLTENA
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAIMANAIATLRVLEQDLGVSLVETGDCVAGHSLGEYTALCAVGAFSLADTARLLKLRG
CCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QAMQAAVPVGEGAMAALLGADIEKATALAEAAAQGEVCEIANDNDPTQVVISGHTGAIER
HHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCHHHHH
AVALVKEHGIKRGVPLPVSAPFHCSLMQPAADAMAEALAETPPSSFSLPVYANVTAAKVS
HHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHCC
DPAEERDLLVQQVTGRVRWRESVLAMRDSGVAHFIELGGKVLGPMVGRIDKEAQITSAIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
MEDLEALAKEIG
HHHHHHHHHHCC
>Mature Secondary Structure
MRAFIFPGQGSQKVGMGADLADASAAARAVFEEVDDALSQTLSDIMRDGPEADLTLTENA
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAIMANAIATLRVLEQDLGVSLVETGDCVAGHSLGEYTALCAVGAFSLADTARLLKLRG
CCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QAMQAAVPVGEGAMAALLGADIEKATALAEAAAQGEVCEIANDNDPTQVVISGHTGAIER
HHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCHHHHH
AVALVKEHGIKRGVPLPVSAPFHCSLMQPAADAMAEALAETPPSSFSLPVYANVTAAKVS
HHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHCC
DPAEERDLLVQQVTGRVRWRESVLAMRDSGVAHFIELGGKVLGPMVGRIDKEAQITSAIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
MEDLEALAKEIG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]