Click here to switch to the map view.

The map label for this gene is ldcA [C]

Identifier: 85374296

GI number: 85374296

Start: 1526494

End: 1527324

Strand: Reverse

Name: ldcA [C]

Synonym: ELI_07345

Alternate gene names: 85374296

Gene position: 1527324-1526494 (Counterclockwise)

Preceding gene: 85374298

Following gene: 85374295

Centisome position: 50.04

GC content: 65.94

Gene sequence:

>831_bases
ATGACCCGCATCGCCATCTGTGCGCCCGCGACTGCCATCACCCGCGACCACGCGGCAGCGATGGAGGCATTCGTCGCCGC
CGAATACCCGCAGCATTCGGTGTGGTTTCACGACCAATGCTTTGAGACCTTCGCGCACTACGCGGGTGACGACCTCACGC
GCCTCAATGCGTTGGTCGAATGCGCCAACAATCCCGAATTCGACGCGGTCTGGTTCGCCAAGGGCGGCTATGGCTCCAAC
CGCATCGCCCAGGCTGCGACCGCGCGGATGAACGATGCTGCGCGCGAGAAGACCTATGTCGGCTTTTCCGACATGGGCTA
CATGCTCGCCGCGCTCTATCGCGCCGGGATTGGGCAGCCGGTCCATGGCTCGATGCCGGTCAGCGCGCGCAGCGAACGGG
GGCGAGGCGCGCTGCGCCGCGTGCTCAACTGGTTCTCCGGCGATGCGAGCGGGGTCGAGCCCAGCGTGGACGGCAAGACG
CCGACGGTCGCCTTCAATCTCATCACGCTCGCCATGCTGGTCGATACGCCGCTGCTGCCGGACCTTACCGGGCATGTCGT
AATGGTCGAGGAAGTCAGCGAGCATCTCTACGCGATCGATCGCCTGTTCTTCAGCCTGGCGAACACGCTGCCGCGCCTCG
CCGGGCTACGTTTGGGTGCGGTCACGGCTGTGCCCGAGAACGACCGCGACTTCGGCCAGACGCCGGAGGAAATTGCGAAG
TTCTGGTGCGATCGCGCGGGAATTCCCTTTCTCGGCCGGGCCCGCATCGGCCACACGGCGGACAACCACGTCGTGCCGTT
CGGGGTTGCGAGTCCGCCGCAGGCTCCGTAA

Upstream 100 bases:

>100_bases
TCCCCGCGCAGGCGGGGATCCAGCTTACTTTTGTGGAGCAGTCGAATAAAAGCTGGATTCCCGCCTTCGCGGGAATGACG
AATAAGGTTAGAGAGATCGC

Downstream 100 bases:

>100_bases
TCGCGTCTCCAGGACAGGAGATTTCACATGCGCGCATTTATCTTTCCCGGACAGGGCAGCCAGAAGGTCGGTATGGGCGC
GGACCTGGCCGATGCCAGCG

Product: peptidase U61, LD-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTRIAICAPATAITRDHAAAMEAFVAAEYPQHSVWFHDQCFETFAHYAGDDLTRLNALVECANNPEFDAVWFAKGGYGSN
RIAQAATARMNDAAREKTYVGFSDMGYMLAALYRAGIGQPVHGSMPVSARSERGRGALRRVLNWFSGDASGVEPSVDGKT
PTVAFNLITLAMLVDTPLLPDLTGHVVMVEEVSEHLYAIDRLFFSLANTLPRLAGLRLGAVTAVPENDRDFGQTPEEIAK
FWCDRAGIPFLGRARIGHTADNHVVPFGVASPPQAP

Sequences:

>Translated_276_residues
MTRIAICAPATAITRDHAAAMEAFVAAEYPQHSVWFHDQCFETFAHYAGDDLTRLNALVECANNPEFDAVWFAKGGYGSN
RIAQAATARMNDAAREKTYVGFSDMGYMLAALYRAGIGQPVHGSMPVSARSERGRGALRRVLNWFSGDASGVEPSVDGKT
PTVAFNLITLAMLVDTPLLPDLTGHVVMVEEVSEHLYAIDRLFFSLANTLPRLAGLRLGAVTAVPENDRDFGQTPEEIAK
FWCDRAGIPFLGRARIGHTADNHVVPFGVASPPQAP
>Mature_275_residues
TRIAICAPATAITRDHAAAMEAFVAAEYPQHSVWFHDQCFETFAHYAGDDLTRLNALVECANNPEFDAVWFAKGGYGSNR
IAQAATARMNDAAREKTYVGFSDMGYMLAALYRAGIGQPVHGSMPVSARSERGRGALRRVLNWFSGDASGVEPSVDGKTP
TVAFNLITLAMLVDTPLLPDLTGHVVMVEEVSEHLYAIDRLFFSLANTLPRLAGLRLGAVTAVPENDRDFGQTPEEIAKF
WCDRAGIPFLGRARIGHTADNHVVPFGVASPPQAP

Specific function: Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D- Glu-meso-Dap-D-Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling [H]

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 29921; Mature: 29790

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIAICAPATAITRDHAAAMEAFVAAEYPQHSVWFHDQCFETFAHYAGDDLTRLNALVE
CCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHH
CANNPEFDAVWFAKGGYGSNRIAQAATARMNDAAREKTYVGFSDMGYMLAALYRAGIGQP
HCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCCC
VHGSMPVSARSERGRGALRRVLNWFSGDASGVEPSVDGKTPTVAFNLITLAMLVDTPLLP
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DLTGHVVMVEEVSEHLYAIDRLFFSLANTLPRLAGLRLGAVTAVPENDRDFGQTPEEIAK
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEEECCCCCCCCCCCHHHHHH
FWCDRAGIPFLGRARIGHTADNHVVPFGVASPPQAP
HHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
TRIAICAPATAITRDHAAAMEAFVAAEYPQHSVWFHDQCFETFAHYAGDDLTRLNALVE
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHH
CANNPEFDAVWFAKGGYGSNRIAQAATARMNDAAREKTYVGFSDMGYMLAALYRAGIGQP
HCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCCC
VHGSMPVSARSERGRGALRRVLNWFSGDASGVEPSVDGKTPTVAFNLITLAMLVDTPLLP
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DLTGHVVMVEEVSEHLYAIDRLFFSLANTLPRLAGLRLGAVTAVPENDRDFGQTPEEIAK
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEEECCCCCCCCCCCHHHHHH
FWCDRAGIPFLGRARIGHTADNHVVPFGVASPPQAP
HHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]