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The map label for this gene is fabA [H]

Identifier: 85374176

GI number: 85374176

Start: 1395430

End: 1395939

Strand: Reverse

Name: fabA [H]

Synonym: ELI_06745

Alternate gene names: 85374176

Gene position: 1395939-1395430 (Counterclockwise)

Preceding gene: 85374177

Following gene: 85374175

Centisome position: 45.73

GC content: 61.76

Gene sequence:

>510_bases
ATGACAGATTTCCCAACCAGTTTCGACCGCGACGAGCTGCTGAAATGCGCGCGGGGCGAATTGTTCGGCCCGGGCAATGC
GCAATTGCCCGAGCCGCCGATGCTGATGATGGACCGGATCACGGATATTTCCGGTGACGGCGGCGAGCATGGCAAGGGCC
ATGTCGTGGCGGAATTCGATATCACGCCCGACCTGTGGTTCTTCGAGTGTCACTTTCCCGGCAATCCGATCATGCCCGGC
TGCCTCGGCCTCGACGGCCTGTGGCAACTGACCGGCTTCAACCTCGGCTGGCGGGGCTGGAAGGGGCGCGGCTATGCGCT
CGGCGTCGGCGAGGTCAAGCTCACCGGCATGGTGCGGCCCGATCGCAAGATGCTGAAATATTTCGTCGATTTTACCAAGG
CGGTACAGATCAGGCGTCTGACGATGGGCGTGGCCGATGGCCGGGTCGAGGCCGACGGTGAAGTCATCTACCAGGTCAAA
GACATGAAAGTGGCCCTTTCGGAGGCCTGA

Upstream 100 bases:

>100_bases
TGGGATGCCGGAGAGACTCTCCAGCGCCCTTTCCACCACGAATACGGGGTGCTAGTCGCCCCATCGATCAATCGACACAC
ATGGGGGAGCACCACCGGGG

Downstream 100 bases:

>100_bases
GGGGGATTATGCGTCGCGTAGTAGTCACCGGATTGGGGATCGTCTCCTCGATCGGCAACAATGCAGATGAGGTGCTCGCC
GCGCTGAAAGCGGGCAAGTC

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MTDFPTSFDRDELLKCARGELFGPGNAQLPEPPMLMMDRITDISGDGGEHGKGHVVAEFDITPDLWFFECHFPGNPIMPG
CLGLDGLWQLTGFNLGWRGWKGRGYALGVGEVKLTGMVRPDRKMLKYFVDFTKAVQIRRLTMGVADGRVEADGEVIYQVK
DMKVALSEA

Sequences:

>Translated_169_residues
MTDFPTSFDRDELLKCARGELFGPGNAQLPEPPMLMMDRITDISGDGGEHGKGHVVAEFDITPDLWFFECHFPGNPIMPG
CLGLDGLWQLTGFNLGWRGWKGRGYALGVGEVKLTGMVRPDRKMLKYFVDFTKAVQIRRLTMGVADGRVEADGEVIYQVK
DMKVALSEA
>Mature_168_residues
TDFPTSFDRDELLKCARGELFGPGNAQLPEPPMLMMDRITDISGDGGEHGKGHVVAEFDITPDLWFFECHFPGNPIMPGC
LGLDGLWQLTGFNLGWRGWKGRGYALGVGEVKLTGMVRPDRKMLKYFVDFTKAVQIRRLTMGVADGRVEADGEVIYQVKD
MKVALSEA

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=168, Percent_Identity=55.3571428571429, Blast_Score=187, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18771; Mature: 18640

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFPTSFDRDELLKCARGELFGPGNAQLPEPPMLMMDRITDISGDGGEHGKGHVVAEFD
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEE
ITPDLWFFECHFPGNPIMPGCLGLDGLWQLTGFNLGWRGWKGRGYALGVGEVKLTGMVRP
CCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCEEEEEEECC
DRKMLKYFVDFTKAVQIRRLTMGVADGRVEADGEVIYQVKDMKVALSEA
HHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCEEEEEEECEEEEECCC
>Mature Secondary Structure 
TDFPTSFDRDELLKCARGELFGPGNAQLPEPPMLMMDRITDISGDGGEHGKGHVVAEFD
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEE
ITPDLWFFECHFPGNPIMPGCLGLDGLWQLTGFNLGWRGWKGRGYALGVGEVKLTGMVRP
CCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCEEEEEEECC
DRKMLKYFVDFTKAVQIRRLTMGVADGRVEADGEVIYQVKDMKVALSEA
HHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCEEEEEEECEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA