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The map label for this gene is ubiE [C]

Identifier: 85374177

GI number: 85374177

Start: 1396047

End: 1396802

Strand: Reverse

Name: ubiE [C]

Synonym: ELI_06750

Alternate gene names: 85374177

Gene position: 1396802-1396047 (Counterclockwise)

Preceding gene: 85374178

Following gene: 85374176

Centisome position: 45.76

GC content: 66.53

Gene sequence:

>756_bases
ATGATCCGCTGCGCTGTCTTGTGCCTGCCCGTGCTGGCCATGCTGCCCGCATGCGAGCGGGTGCCCGGCAGCGACACCAG
CGACCGGCTGGCCAGCGCCATTCAATTCCCCGAGCCCGATCGTCCGGTCTCCAAGCTGGGAGCCAATGCTTTCAGCACCG
AAACCGCCCGCGACAGCGTTGGCGAAGCGCGCAAGGTCATGGATTTCGCCGCGATCGAGCCGGGCATGACGGTCGCCGAT
ATCGGCGCGGGCGAGGGCTATTACACCGTGCGTCTCGCCACCCGCGTGGGAGAGAGCGGCCGCGTGCTGGCACAGGATAT
CGATCCCGATGCGCTGCAGCGGCTCGGCACGCGTGTCGAGCGCGAGCGGCTCGACAATGTCTCCATCAAGCTCGGCGCGC
CCGACGATCCGCGGCTGCCCGATGACAGTTTCGACCGCGTCTTCATGGTGCATATGTATCATGAGGTCGAGGAACCCTAC
GCCTTCCTGTGGCGGCTGTGGCCTTCGCTGAAAGAAGGCGGGCAGGCGATTGTCGTCGACGTGGATCGTCCGACCGACCA
GCACGGCATCGATCCCTTCCTGCTCAAATGCGAATTCGAGCAGGTCGGTTTCGAGCTCGAGATGTTCCGCGATGCGCCGG
AACTGGCCGGTTACTACGCGCAATTCCGCCGCGCGGCGACCCGGCCGGAGCCGGGCGAGATCGAACCGTGCAAGGGCGAG
CCGCGCCGGGCCACGGGCGGGGATACCCGGAACTAG

Upstream 100 bases:

>100_bases
GCTCCCCCGATGATGTGCTCGACGGCGCGCTCGACCCCTACATTTCCGCCGCCCTCGCACAGCGCGTGACGGGCGAGACA
GTGGAAGTGGAAGACGTCGA

Downstream 100 bases:

>100_bases
CTGGCGATGGGATGCCGGAGAGACTCTCCAGCGCCCTTTCCACCACGAATACGGGGTGCTAGTCGCCCCATCGATCAATC
GACACACATGGGGGAGCACC

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase UbiE/COQ5 Family; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; Generic Methyltransferase; Methyltransferase Domain Family Protein; Methylase

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MIRCAVLCLPVLAMLPACERVPGSDTSDRLASAIQFPEPDRPVSKLGANAFSTETARDSVGEARKVMDFAAIEPGMTVAD
IGAGEGYYTVRLATRVGESGRVLAQDIDPDALQRLGTRVERERLDNVSIKLGAPDDPRLPDDSFDRVFMVHMYHEVEEPY
AFLWRLWPSLKEGGQAIVVDVDRPTDQHGIDPFLLKCEFEQVGFELEMFRDAPELAGYYAQFRRAATRPEPGEIEPCKGE
PRRATGGDTRN

Sequences:

>Translated_251_residues
MIRCAVLCLPVLAMLPACERVPGSDTSDRLASAIQFPEPDRPVSKLGANAFSTETARDSVGEARKVMDFAAIEPGMTVAD
IGAGEGYYTVRLATRVGESGRVLAQDIDPDALQRLGTRVERERLDNVSIKLGAPDDPRLPDDSFDRVFMVHMYHEVEEPY
AFLWRLWPSLKEGGQAIVVDVDRPTDQHGIDPFLLKCEFEQVGFELEMFRDAPELAGYYAQFRRAATRPEPGEIEPCKGE
PRRATGGDTRN
>Mature_251_residues
MIRCAVLCLPVLAMLPACERVPGSDTSDRLASAIQFPEPDRPVSKLGANAFSTETARDSVGEARKVMDFAAIEPGMTVAD
IGAGEGYYTVRLATRVGESGRVLAQDIDPDALQRLGTRVERERLDNVSIKLGAPDDPRLPDDSFDRVFMVHMYHEVEEPY
AFLWRLWPSLKEGGQAIVVDVDRPTDQHGIDPFLLKCEFEQVGFELEMFRDAPELAGYYAQFRRAATRPEPGEIEPCKGE
PRRATGGDTRN

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27857; Mature: 27857

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRCAVLCLPVLAMLPACERVPGSDTSDRLASAIQFPEPDRPVSKLGANAFSTETARDSV
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCHHCCHHHHHHH
GEARKVMDFAAIEPGMTVADIGAGEGYYTVRLATRVGESGRVLAQDIDPDALQRLGTRVE
HHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHH
RERLDNVSIKLGAPDDPRLPDDSFDRVFMVHMYHEVEEPYAFLWRLWPSLKEGGQAIVVD
HHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDRPTDQHGIDPFLLKCEFEQVGFELEMFRDAPELAGYYAQFRRAATRPEPGEIEPCKGE
CCCCCCCCCCCCEEEEEEHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PRRATGGDTRN
CCCCCCCCCCC
>Mature Secondary Structure
MIRCAVLCLPVLAMLPACERVPGSDTSDRLASAIQFPEPDRPVSKLGANAFSTETARDSV
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCHHCCHHHHHHH
GEARKVMDFAAIEPGMTVADIGAGEGYYTVRLATRVGESGRVLAQDIDPDALQRLGTRVE
HHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHH
RERLDNVSIKLGAPDDPRLPDDSFDRVFMVHMYHEVEEPYAFLWRLWPSLKEGGQAIVVD
HHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDRPTDQHGIDPFLLKCEFEQVGFELEMFRDAPELAGYYAQFRRAATRPEPGEIEPCKGE
CCCCCCCCCCCCEEEEEEHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PRRATGGDTRN
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA