Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 85374164

GI number: 85374164

Start: 1384624

End: 1385376

Strand: Reverse

Name: nuoC

Synonym: ELI_06685

Alternate gene names: 85374164

Gene position: 1385376-1384624 (Counterclockwise)

Preceding gene: 85374165

Following gene: 85374163

Centisome position: 45.39

GC content: 62.28

Gene sequence:

>753_bases
ATGGCTGTCGTTCACTCCGCCCCCAAATATGCCTCCAACGACGGCGTGCGCGGCACGCTGGTGAAGGCGCTGGGCGATTA
TGTCGCCGCTTCGCACGAGAAGTATGGCGAGATCATCATCACCGTCGAGCGCGATGCTATCGAAGACGTGCTGCGCACCC
TGCGCGACGATCACGATTACCAGCAACTGATGGAAATCGCGGGGGTCGACTATCCCGAGCGGCCCGAGCGGTTCGAAGTC
GTCTACATGCTGCTCAGTCTGACGAAGAACCACCGCGTGATGGTCAAGGTAAGCACGGACGAGAAAACGCCTGTTCCGAC
CGTCACGACGCTGTGGCCCAATGCCGGCTGGCTCGAGCGTGAAGTGTTCGACCTCTACGGCGTATTGTTCGACGGCAATA
CCGATCTTCGCCGCATCCTTACCGATTACGGCTTCGAAGGGCACCCCTTCCGCAAGGACTTCCCGCTGACTGGCTATACC
GAGCTGCGCTATTCCGAAGAGGAGCAGCGCGTCGTGTACGAACCGGTCGAGCTGGCGCAGGACCTGCGCACGTTCGATTT
TCTCAGCCCATGGGAAGGCATGACCCCGCCGCTGCCGGGCGACGAGAAGGCCGACATGCCTCCGATCGACGATCCGATGG
TGACCGAAGGACCGGAAGACACCGGTGCGGGTGCCAGGGCGAACGCCAAGGCCGCCGAGGGCACGCCTGCCGATCCGCCT
GCCATGGATGACGAAGAGGAGGACGACGCATGA

Upstream 100 bases:

>100_bases
CTGCCCGCCGACCGCGGAAGCGCTGCTCTACGGCGTGATGCAGTTGCAGCGGAAGATCCGCCGCTCCGGGACGATCGAGC
GATGAGAGGCTCGCGCTAAG

Downstream 100 bases:

>100_bases
TGCCGGTGCGCGCGTCCACTTTTGCGGCGACCGTCTCGCTGGCGCTTGCGGCCTGCTCGCAAGCCGGCGAAGAGCAGAGC
GCGGACGATTTCGCCAATCG

Product: NADH dehydrogenase I, C subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAVVHSAPKYASNDGVRGTLVKALGDYVAASHEKYGEIIITVERDAIEDVLRTLRDDHDYQQLMEIAGVDYPERPERFEV
VYMLLSLTKNHRVMVKVSTDEKTPVPTVTTLWPNAGWLEREVFDLYGVLFDGNTDLRRILTDYGFEGHPFRKDFPLTGYT
ELRYSEEEQRVVYEPVELAQDLRTFDFLSPWEGMTPPLPGDEKADMPPIDDPMVTEGPEDTGAGARANAKAAEGTPADPP
AMDDEEEDDA

Sequences:

>Translated_250_residues
MAVVHSAPKYASNDGVRGTLVKALGDYVAASHEKYGEIIITVERDAIEDVLRTLRDDHDYQQLMEIAGVDYPERPERFEV
VYMLLSLTKNHRVMVKVSTDEKTPVPTVTTLWPNAGWLEREVFDLYGVLFDGNTDLRRILTDYGFEGHPFRKDFPLTGYT
ELRYSEEEQRVVYEPVELAQDLRTFDFLSPWEGMTPPLPGDEKADMPPIDDPMVTEGPEDTGAGARANAKAAEGTPADPP
AMDDEEEDDA
>Mature_249_residues
AVVHSAPKYASNDGVRGTLVKALGDYVAASHEKYGEIIITVERDAIEDVLRTLRDDHDYQQLMEIAGVDYPERPERFEVV
YMLLSLTKNHRVMVKVSTDEKTPVPTVTTLWPNAGWLEREVFDLYGVLFDGNTDLRRILTDYGFEGHPFRKDFPLTGYTE
LRYSEEEQRVVYEPVELAQDLRTFDFLSPWEGMTPPLPGDEKADMPPIDDPMVTEGPEDTGAGARANAKAAEGTPADPPA
MDDEEEDDA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=185, Percent_Identity=49.7297297297297, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI145693162, Length=153, Percent_Identity=35.9477124183007, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=205, Percent_Identity=44.390243902439, Blast_Score=167, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI32563621, Length=205, Percent_Identity=44.390243902439, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24656494, Length=196, Percent_Identity=48.469387755102, Blast_Score=181, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_ERYLH (Q2NA62)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458226.1
- STRING:   Q2NA62
- GeneID:   3869269
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_06685
- NMPDR:   fig|314225.3.peg.1714
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   YVELRYS
- BioCyc:   ELIT314225:ELI_06685-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 28114; Mature: 27982

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVHSAPKYASNDGVRGTLVKALGDYVAASHEKYGEIIITVERDAIEDVLRTLRDDHDY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCHH
QQLMEIAGVDYPERPERFEVVYMLLSLTKNHRVMVKVSTDEKTPVPTVTTLWPNAGWLER
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHH
EVFDLYGVLFDGNTDLRRILTDYGFEGHPFRKDFPLTGYTELRYSEEEQRVVYEPVELAQ
HHHHHHHHEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEECCCHHHEEECHHHHHH
DLRTFDFLSPWEGMTPPLPGDEKADMPPIDDPMVTEGPEDTGAGARANAKAAEGTPADPP
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AMDDEEEDDA
CCCCCCCCCC
>Mature Secondary Structure 
AVVHSAPKYASNDGVRGTLVKALGDYVAASHEKYGEIIITVERDAIEDVLRTLRDDHDY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCHH
QQLMEIAGVDYPERPERFEVVYMLLSLTKNHRVMVKVSTDEKTPVPTVTTLWPNAGWLER
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHH
EVFDLYGVLFDGNTDLRRILTDYGFEGHPFRKDFPLTGYTELRYSEEEQRVVYEPVELAQ
HHHHHHHHEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEECCCHHHEEECHHHHHH
DLRTFDFLSPWEGMTPPLPGDEKADMPPIDDPMVTEGPEDTGAGARANAKAAEGTPADPP
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AMDDEEEDDA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA