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The map label for this gene is coaX

Identifier: 85374145

GI number: 85374145

Start: 1368512

End: 1369291

Strand: Reverse

Name: coaX

Synonym: ELI_06590

Alternate gene names: 85374145

Gene position: 1369291-1368512 (Counterclockwise)

Preceding gene: 85374146

Following gene: 85374144

Centisome position: 44.86

GC content: 63.59

Gene sequence:

>780_bases
ATGCTGCTAGCCGCCGATGTCGGGAACACCAATGTCGTCTTCGCGCTGTTCGAAGGCCGCGACATCCGCGCCCGCTGGCG
TATCGCGACCGACCCGCGGCGGACGGGCGACGAATACGCCGTCTGGCTGCTCCAGTTGCTCCAGATCGAGGGTGTGCAGC
GCGAAGAGATTACGCAGATCATCTTTGCCTCCGTGGTCCCCCGCGCGAACCACAACCTCACCGTGCTGTGCGAGAAATAT
TTCGGTATCGCGCCCCTGGTCGCGGGCGAGGGCAAGGCGGCGTGGCCGTTCCAGGCCGATGTCGACCAGCCGAGTTCGCT
GGGCGCCGACCGCGCGCTCAATATCCTCGCCGCGCACGAGAAATATGGCGGCGACCTGATCGTCGTCGATTTCGGCACCG
CGACCAAGCTCGAGGCGATCGATTTCAACGGCACCTACAAGGGCGGAATCATCGCGCCGGGGATCAATCTTTCTCTCGAC
GCACTCGTCGGCAAGACCGCCAAGCTCCCCCGCATCGCCATTCGCGCGCCGGAGACCGCCAGCGTTATCGGACGCAACAC
CGAAGATCAGATGCTGATCGGCGTGTTCTGGGCGCATGTCGCGATGATGGAAGGCCTGATCGAGCGCATGCGCGCGGAGA
TCGGTCGCCCGGCGAAAGTCGTCGCGACCGGCGGGCTTGCCATCCTGTTCGACGAGAAAACCGACATTTTCGACCACGTC
GATGCGGACCTTACCATCGAGGGTCTCGCGATCCTCGCCGAACACGCATCGAAGCAATAA

Upstream 100 bases:

>100_bases
CTCGACGCCGAGGGCACGCTGCAACTGCGCTTGGACGACGGGACCATCCGTGCCATTCACGCCGGCGATGTGATGCTCGC
CTGAAGGAGCCGAGAGAGAC

Downstream 100 bases:

>100_bases
GAGACCTATGAAAAAAGATTACACGCCGGAAGACGAGCTGCTGTTCCTTGCGCTCGGTGGGTCGGGCGAGATCGGCATGA
ACGTCAATCTCTACGGCTGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLLAADVGNTNVVFALFEGRDIRARWRIATDPRRTGDEYAVWLLQLLQIEGVQREEITQIIFASVVPRANHNLTVLCEKY
FGIAPLVAGEGKAAWPFQADVDQPSSLGADRALNILAAHEKYGGDLIVVDFGTATKLEAIDFNGTYKGGIIAPGINLSLD
ALVGKTAKLPRIAIRAPETASVIGRNTEDQMLIGVFWAHVAMMEGLIERMRAEIGRPAKVVATGGLAILFDEKTDIFDHV
DADLTIEGLAILAEHASKQ

Sequences:

>Translated_259_residues
MLLAADVGNTNVVFALFEGRDIRARWRIATDPRRTGDEYAVWLLQLLQIEGVQREEITQIIFASVVPRANHNLTVLCEKY
FGIAPLVAGEGKAAWPFQADVDQPSSLGADRALNILAAHEKYGGDLIVVDFGTATKLEAIDFNGTYKGGIIAPGINLSLD
ALVGKTAKLPRIAIRAPETASVIGRNTEDQMLIGVFWAHVAMMEGLIERMRAEIGRPAKVVATGGLAILFDEKTDIFDHV
DADLTIEGLAILAEHASKQ
>Mature_259_residues
MLLAADVGNTNVVFALFEGRDIRARWRIATDPRRTGDEYAVWLLQLLQIEGVQREEITQIIFASVVPRANHNLTVLCEKY
FGIAPLVAGEGKAAWPFQADVDQPSSLGADRALNILAAHEKYGGDLIVVDFGTATKLEAIDFNGTYKGGIIAPGINLSLD
ALVGKTAKLPRIAIRAPETASVIGRNTEDQMLIGVFWAHVAMMEGLIERMRAEIGRPAKVVATGGLAILFDEKTDIFDHV
DADLTIEGLAILAEHASKQ

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_ERYLH (Q2NA81)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458207.1
- ProteinModelPortal:   Q2NA81
- SMR:   Q2NA81
- STRING:   Q2NA81
- GeneID:   3870382
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_06590
- NMPDR:   fig|314225.3.peg.1733
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   ELIT314225:ELI_06590-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28087; Mature: 28087

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 133-133 BINDING 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAADVGNTNVVFALFEGRDIRARWRIATDPRRTGDEYAVWLLQLLQIEGVQREEITQI
CEEEEECCCCEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
IFASVVPRANHNLTVLCEKYFGIAPLVAGEGKAAWPFQADVDQPSSLGADRALNILAAHE
HHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHEEEEHH
KYGGDLIVVDFGTATKLEAIDFNGTYKGGIIAPGINLSLDALVGKTAKLPRIAIRAPETA
CCCCCEEEEECCCCCEEEEEECCCCCCCCEEECCCCEEHHHHHCCCCCCCEEEEECCCHH
SVIGRNTEDQMLIGVFWAHVAMMEGLIERMRAEIGRPAKVVATGGLAILFDEKTDIFDHV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCHHHHC
DADLTIEGLAILAEHASKQ
CCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MLLAADVGNTNVVFALFEGRDIRARWRIATDPRRTGDEYAVWLLQLLQIEGVQREEITQI
CEEEEECCCCEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
IFASVVPRANHNLTVLCEKYFGIAPLVAGEGKAAWPFQADVDQPSSLGADRALNILAAHE
HHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHEEEEHH
KYGGDLIVVDFGTATKLEAIDFNGTYKGGIIAPGINLSLDALVGKTAKLPRIAIRAPETA
CCCCCEEEEECCCCCEEEEEECCCCCCCCEEECCCCEEHHHHHCCCCCCCEEEEECCCHH
SVIGRNTEDQMLIGVFWAHVAMMEGLIERMRAEIGRPAKVVATGGLAILFDEKTDIFDHV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCHHHHC
DADLTIEGLAILAEHASKQ
CCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA