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The map label for this gene is yfkJ [H]

Identifier: 85373853

GI number: 85373853

Start: 1062417

End: 1062890

Strand: Reverse

Name: yfkJ [H]

Synonym: ELI_05130

Alternate gene names: 85373853

Gene position: 1062890-1062417 (Counterclockwise)

Preceding gene: 85373855

Following gene: 85373851

Centisome position: 34.82

GC content: 63.92

Gene sequence:

>474_bases
ATGAACCAAACTCCTGCCGTCCTGTTCGTCTGCCTCGGCAATATCTGCCGGTCCCCTTTGGCGGAAGCCGCGTTCCGCAA
GGCCAGCGCCGACGCTGGTCTGGACGCCGAGGCCGACAGCGCCGGTACCGCCGCCTATCATGTCGGCGAGCCGCCGGACC
CGCGCAGCGTCAGCACCGCGGCGAAATACGGGATCGACATCGCCCAGTATCGCGGGCGGCAGATCGAGCAGGCGGATTTC
AAGCGCTTCACGCATATCCTTGCGCTGGACCACTCCAACCTCGCCAACATCAAGGCCATGGCGCCGGACAGGCATGACGC
GCATGTCTCGCTGCTGATGGACATGGTGCCGGGCCGCGAAGGTGCTGCGGTCGCCGATCCCTATTACGATGGCGAGGAGC
ATTTCGAATATACGTGGGACGATGTTTGGATGGCTGCTGAAGCCATCGTGGCCAAGCTAGCCGCCGCGAAGTAG

Upstream 100 bases:

>100_bases
GTGGACAGGGCCAGCGCGGTGAACAGGTGACGCATCGATAATCTCCTTCTTGCGCGCCTCCCTATTGCGGGCAGGCGCGA
GGGTCCAGTAGGCAACAGAC

Downstream 100 bases:

>100_bases
CTGTACGCCGTAGTCCCGCTCGAAGAGGTAAAGCAGCACTCTCGCGGCCTCACCGCGCTCGGAGCTGAGGCCGCCGTCGC
GTTCTATGAGGAGGCGCGCG

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNQTPAVLFVCLGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVGEPPDPRSVSTAAKYGIDIAQYRGRQIEQADF
KRFTHILALDHSNLANIKAMAPDRHDAHVSLLMDMVPGREGAAVADPYYDGEEHFEYTWDDVWMAAEAIVAKLAAAK

Sequences:

>Translated_157_residues
MNQTPAVLFVCLGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVGEPPDPRSVSTAAKYGIDIAQYRGRQIEQADF
KRFTHILALDHSNLANIKAMAPDRHDAHVSLLMDMVPGREGAAVADPYYDGEEHFEYTWDDVWMAAEAIVAKLAAAK
>Mature_157_residues
MNQTPAVLFVCLGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVGEPPDPRSVSTAAKYGIDIAQYRGRQIEQADF
KRFTHILALDHSNLANIKAMAPDRHDAHVSLLMDMVPGREGAAVADPYYDGEEHFEYTWDDVWMAAEAIVAKLAAAK

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=153, Percent_Identity=39.2156862745098, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI6005988, Length=153, Percent_Identity=39.2156862745098, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI96304457, Length=80, Percent_Identity=47.5, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325330, Length=152, Percent_Identity=36.1842105263158, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI78706766, Length=146, Percent_Identity=36.3013698630137, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI78706768, Length=146, Percent_Identity=36.3013698630137, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI78706764, Length=124, Percent_Identity=37.9032258064516, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI78706770, Length=156, Percent_Identity=37.1794871794872, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI78706772, Length=156, Percent_Identity=37.1794871794872, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI78711846, Length=127, Percent_Identity=35.4330708661417, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16976; Mature: 16976

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTPAVLFVCLGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVGEPPDPRSVSTA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHH
AKYGIDIAQYRGRQIEQADFKRFTHILALDHSNLANIKAMAPDRHDAHVSLLMDMVPGRE
HHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCC
GAAVADPYYDGEEHFEYTWDDVWMAAEAIVAKLAAAK
CCEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQTPAVLFVCLGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVGEPPDPRSVSTA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHH
AKYGIDIAQYRGRQIEQADFKRFTHILALDHSNLANIKAMAPDRHDAHVSLLMDMVPGRE
HHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCC
GAAVADPYYDGEEHFEYTWDDVWMAAEAIVAKLAAAK
CCEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]