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The map label for this gene is ubiB [C]

Identifier: 85373855

GI number: 85373855

Start: 1064717

End: 1066051

Strand: Reverse

Name: ubiB [C]

Synonym: ELI_05140

Alternate gene names: 85373855

Gene position: 1066051-1064717 (Counterclockwise)

Preceding gene: 85373861

Following gene: 85373853

Centisome position: 34.93

GC content: 62.85

Gene sequence:

>1335_bases
ATGTCCGACTCCGATAATCCCCCGCGGCACCGCGCGGTTCCCAGCGGGCGCATTTCGCGCCTTGCGGGTTTTGGCCGGTT
GGCGGGCGGCGTCGCGGGATCGATGCTAGGCGAAGGCGCGCGGAGACTTGCTGCGGGCCAGCGGCCGAAGCTCGATGAAC
TTATTCTCACCACCGGCAATGCCAGGCGGCTGACGGAACGGCTGGCTCACTTGCGCGGAGCCGCCATGAAGCTCGGCCAG
ATGATCAGCATGGATGCCGGCGACATGTTGCCGCCGGAACTATCGCAGATCCTCGCCAGCCTGCGCGACCAGGCCAATTT
CATGCCGCCGAAACAACTCGACAAGGTTCTCGCGGCGGAATGGGGCAAGGATTGGCGGAAGCAATTCCGCCGCTTCGAGC
CTCGGCCCATCGCCGCCGCCAGCATCGGCCAGGTCCATCGTGCGGTCACTCGCGATGGCGAGACCCTGGCGATCAAGGTG
CAGTATCCCGGCGTCGCGGAGAGCATCGACAGCGATGTCGACAATGTTGCGACATTGCTACGCGTCTCGGGATTGCTGCC
CAAGGAGCTCGATATCGGTCCGCTCCTGACGGCTGCCAAGGAGCAACTGCACGAGGAGGCAGACTATATTCGCGAGGGCG
AGCAGATGATGCTCTATCGCGAAAGGCTCGCCGACCTGCCTGTCTTCGTCATACCCGAACTGCATAAAGAGCTGACCAGC
GAGCGCATCCTGGCCATGTCCTTCGTCGAAGGTATTCCGATCGAAAGTCTGGAGCACGAGCCGCAGGACCTGCGCAACAC
CGTGTTCGAACAGATGATGCGACTGGTGGCGCGCGAGTTGTTCGAATTCGGGGTCATGCAGACCGACCCGAACTTCGCAA
ACTTCCGTTACCAGCGCGATACGGGGCGCGTCGTCCTGCTGGATTTCGGTGCAACCCGCGAAGTCGATGACAAGATACGG
ATTGCCTATCGGCGATTGTTGGAAGCCGGACTTGCCGAAGACAAACTGGGGATCAAGCAGGAGGCTTTACGGGCAGGGTT
CATGAGCGCAGCCGTCGTCGAGCTTTATCCCGAGCGCGTCGACCGCATGATCGACATCATCGTCAACGAGATGAGCCAGG
ACGCGCCCTTCGATTTCGGCGACCGCAGCTTCGTGCCGCTGTTGCGCGATGAAGGCATGGCGATCGCTCAGGACCGCCGG
ACCTGGCACCTGCCGCCGGTGGAAACGCTGTTCGTGCAGCGCAAGGTGAGCGGCACGGCCCTGCTCGGCGCGCGGCTGAA
AGCGGTGGTGAATGTACGCGCGGTCGTCGAAGAGGTCCTCGCAGCGACGGCGTGA

Upstream 100 bases:

>100_bases
CAGGCCGGCATAGCCAAGCCACATCGCCATCGGCGGAACACTATCCTGCGCGGCAGGTTTCTCCTGCATATCCCTCATTT
CTGTGAAAACGGCCCCCTAC

Downstream 100 bases:

>100_bases
TGCCTAACCGGTTTGCTGCGCTGCAATCCAGCGGTCGATATGCGAGTCCAGCACATCGAGCGGAACTGCACCATTTTCCA
GCACCGCATCATGGAAGGCG

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSDSDNPPRHRAVPSGRISRLAGFGRLAGGVAGSMLGEGARRLAAGQRPKLDELILTTGNARRLTERLAHLRGAAMKLGQ
MISMDAGDMLPPELSQILASLRDQANFMPPKQLDKVLAAEWGKDWRKQFRRFEPRPIAAASIGQVHRAVTRDGETLAIKV
QYPGVAESIDSDVDNVATLLRVSGLLPKELDIGPLLTAAKEQLHEEADYIREGEQMMLYRERLADLPVFVIPELHKELTS
ERILAMSFVEGIPIESLEHEPQDLRNTVFEQMMRLVARELFEFGVMQTDPNFANFRYQRDTGRVVLLDFGATREVDDKIR
IAYRRLLEAGLAEDKLGIKQEALRAGFMSAAVVELYPERVDRMIDIIVNEMSQDAPFDFGDRSFVPLLRDEGMAIAQDRR
TWHLPPVETLFVQRKVSGTALLGARLKAVVNVRAVVEEVLAATA

Sequences:

>Translated_444_residues
MSDSDNPPRHRAVPSGRISRLAGFGRLAGGVAGSMLGEGARRLAAGQRPKLDELILTTGNARRLTERLAHLRGAAMKLGQ
MISMDAGDMLPPELSQILASLRDQANFMPPKQLDKVLAAEWGKDWRKQFRRFEPRPIAAASIGQVHRAVTRDGETLAIKV
QYPGVAESIDSDVDNVATLLRVSGLLPKELDIGPLLTAAKEQLHEEADYIREGEQMMLYRERLADLPVFVIPELHKELTS
ERILAMSFVEGIPIESLEHEPQDLRNTVFEQMMRLVARELFEFGVMQTDPNFANFRYQRDTGRVVLLDFGATREVDDKIR
IAYRRLLEAGLAEDKLGIKQEALRAGFMSAAVVELYPERVDRMIDIIVNEMSQDAPFDFGDRSFVPLLRDEGMAIAQDRR
TWHLPPVETLFVQRKVSGTALLGARLKAVVNVRAVVEEVLAATA
>Mature_443_residues
SDSDNPPRHRAVPSGRISRLAGFGRLAGGVAGSMLGEGARRLAAGQRPKLDELILTTGNARRLTERLAHLRGAAMKLGQM
ISMDAGDMLPPELSQILASLRDQANFMPPKQLDKVLAAEWGKDWRKQFRRFEPRPIAAASIGQVHRAVTRDGETLAIKVQ
YPGVAESIDSDVDNVATLLRVSGLLPKELDIGPLLTAAKEQLHEEADYIREGEQMMLYRERLADLPVFVIPELHKELTSE
RILAMSFVEGIPIESLEHEPQDLRNTVFEQMMRLVARELFEFGVMQTDPNFANFRYQRDTGRVVLLDFGATREVDDKIRI
AYRRLLEAGLAEDKLGIKQEALRAGFMSAAVVELYPERVDRMIDIIVNEMSQDAPFDFGDRSFVPLLRDEGMAIAQDRRT
WHLPPVETLFVQRKVSGTALLGARLKAVVNVRAVVEEVLAATA

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=439, Percent_Identity=36.9020501138952, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI27363457, Length=438, Percent_Identity=36.7579908675799, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI217416386, Length=431, Percent_Identity=33.8747099767981, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI40254938, Length=307, Percent_Identity=29.9674267100977, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI41393593, Length=267, Percent_Identity=29.2134831460674, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI217035081, Length=237, Percent_Identity=29.957805907173, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI2367309, Length=200, Percent_Identity=31.5, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32565180, Length=437, Percent_Identity=36.6132723112128, Blast_Score=288, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17559152, Length=300, Percent_Identity=29.3333333333333, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321319, Length=438, Percent_Identity=36.3013698630137, Blast_Score=292, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6323282, Length=363, Percent_Identity=23.1404958677686, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI18859849, Length=434, Percent_Identity=34.331797235023, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24662575, Length=275, Percent_Identity=26.9090909090909, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI22024280, Length=291, Percent_Identity=25.7731958762887, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 49581; Mature: 49450

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSDNPPRHRAVPSGRISRLAGFGRLAGGVAGSMLGEGARRLAAGQRPKLDELILTTGN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCC
ARRLTERLAHLRGAAMKLGQMISMDAGDMLPPELSQILASLRDQANFMPPKQLDKVLAAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
WGKDWRKQFRRFEPRPIAAASIGQVHRAVTRDGETLAIKVQYPGVAESIDSDVDNVATLL
HCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCHHHHHHHHH
RVSGLLPKELDIGPLLTAAKEQLHEEADYIREGEQMMLYRERLADLPVFVIPELHKELTS
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHH
ERILAMSFVEGIPIESLEHEPQDLRNTVFEQMMRLVARELFEFGVMQTDPNFANFRYQRD
HHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEEECC
TGRVVLLDFGATREVDDKIRIAYRRLLEAGLAEDKLGIKQEALRAGFMSAAVVELYPERV
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DRMIDIIVNEMSQDAPFDFGDRSFVPLLRDEGMAIAQDRRTWHLPPVETLFVQRKVSGTA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCEEECCCCEECCCCHHHHHHHHHCCCHH
LLGARLKAVVNVRAVVEEVLAATA
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDSDNPPRHRAVPSGRISRLAGFGRLAGGVAGSMLGEGARRLAAGQRPKLDELILTTGN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCC
ARRLTERLAHLRGAAMKLGQMISMDAGDMLPPELSQILASLRDQANFMPPKQLDKVLAAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
WGKDWRKQFRRFEPRPIAAASIGQVHRAVTRDGETLAIKVQYPGVAESIDSDVDNVATLL
HCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCHHHHHHHHH
RVSGLLPKELDIGPLLTAAKEQLHEEADYIREGEQMMLYRERLADLPVFVIPELHKELTS
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHH
ERILAMSFVEGIPIESLEHEPQDLRNTVFEQMMRLVARELFEFGVMQTDPNFANFRYQRD
HHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEEECC
TGRVVLLDFGATREVDDKIRIAYRRLLEAGLAEDKLGIKQEALRAGFMSAAVVELYPERV
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DRMIDIIVNEMSQDAPFDFGDRSFVPLLRDEGMAIAQDRRTWHLPPVETLFVQRKVSGTA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCEEECCCCEECCCCHHHHHHHHHCCCHH
LLGARLKAVVNVRAVVEEVLAATA
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]