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The map label for this gene is aroB

Identifier: 85373820

GI number: 85373820

Start: 1021819

End: 1022928

Strand: Reverse

Name: aroB

Synonym: ELI_04965

Alternate gene names: 85373820

Gene position: 1022928-1021819 (Counterclockwise)

Preceding gene: 85373821

Following gene: 85373819

Centisome position: 33.51

GC content: 62.07

Gene sequence:

>1110_bases
ATGGCTGTGATTCCGGTCGAACTGGCAGGGCGCGGATACCAAGTCCACGTCGGACGCGACGTGATCGATCGGCTCGGGTC
GCTGGCCGCGCCCTTTGTGCGAAAATCGCGCCTCGTAGTCGTCGCTGACACGAACGCATGGCGTCATCACGGCGAACGTT
TCTCGCAGGCGGCGCATTCTGCCGGCTGGGCCATCGCTCTCTACGAAGTGCCACCCGGCGAGGGCTCAAAAAGCTGGGCG
AGCCTGCAGCGACTGACCGATTGGTTGCTGGAGCAGGAGGTTGAGCGCGGCAACCATGTGTTCGCGCTCGGCGGCGGAGT
CGTCGGCGACCTGACCGGCTTCGCCTGTGCGATCCTGAAGCGCGGCTGCGGCTTCATACAAATTCCCACGACCTTGCTGG
CTCAGGTCGACAGTTCTGTCGGCGGCAAGACGGCGATCAATAGTTCGACAGGAAAAAACCTGATCGGCGCATTTCACCAA
CCATCGCTTGTGTTGGCCGACCTTGCGACTCTCGACACCTTGCCCGAACGCGAAATGCGTTCAGGCTATGCCGAGGTGCT
CAAGTACGGCGTGTTGGGCGACCGGGCGTTTTTCGACTGGCTGCAGCACAACGGATCGCAGGTTCTGGCGCGCGATCCCG
AGGCGCTGGAATATGCCGTCGCCACCAGTGTCGCAGCCAAGGCCCGGATCGTTGCCGAAGACGAGCGCGAGACGACCGGC
GCAAGGGCGCTGCTTAATCTCGGTCATACGTTCGGGCACGCGCTGGAAGCCCAGATGGGCTTTTCCGACAGATTGCTGCA
TGGCGAAGGCGTGGCGGCAGGCATGGTGCTTGCCGCACGCTACTCGGCCCGCCGCGGAGATCTCGGCGATAGCGATGCTT
CGCTTATCACAAGAGCCGTCGAGGGCGCCGGCTTGCCCTCCGAGATAGCGGCGCTCGACATGGATACAGATGGTGCCGAA
CTCGTCACTCACATGCTGCACGACAAGAAGATGGATGCGGGCACCCTGCCCTTCCTCTTGCTGCGCAGCATCGGTGCAGC
ATATCTTGCGAAGGACGTCGATCTGAAAGACGTCGCCGCTTTTCTCGATGAGCAACTGCAAGCACATTGA

Upstream 100 bases:

>100_bases
GTGAGCGCGAGAAGTTCTATTCGCAGGCTCCGATCCGGGTAAGCAGCGGTGACGGACCGCACTTGCGGACCGCAACGCAA
ATCCTGGAGGCAATCGACCG

Downstream 100 bases:

>100_bases
CGCGGGGCCATGCTGCGGGCGATTGTGCGCAGCATGACCGAATTCATCGACCTCTCGATTCCTATCACCAATGACGTGAT
TTCCGACCCTGAAGTCATGC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MAVIPVELAGRGYQVHVGRDVIDRLGSLAAPFVRKSRLVVVADTNAWRHHGERFSQAAHSAGWAIALYEVPPGEGSKSWA
SLQRLTDWLLEQEVERGNHVFALGGGVVGDLTGFACAILKRGCGFIQIPTTLLAQVDSSVGGKTAINSSTGKNLIGAFHQ
PSLVLADLATLDTLPEREMRSGYAEVLKYGVLGDRAFFDWLQHNGSQVLARDPEALEYAVATSVAAKARIVAEDERETTG
ARALLNLGHTFGHALEAQMGFSDRLLHGEGVAAGMVLAARYSARRGDLGDSDASLITRAVEGAGLPSEIAALDMDTDGAE
LVTHMLHDKKMDAGTLPFLLLRSIGAAYLAKDVDLKDVAAFLDEQLQAH

Sequences:

>Translated_369_residues
MAVIPVELAGRGYQVHVGRDVIDRLGSLAAPFVRKSRLVVVADTNAWRHHGERFSQAAHSAGWAIALYEVPPGEGSKSWA
SLQRLTDWLLEQEVERGNHVFALGGGVVGDLTGFACAILKRGCGFIQIPTTLLAQVDSSVGGKTAINSSTGKNLIGAFHQ
PSLVLADLATLDTLPEREMRSGYAEVLKYGVLGDRAFFDWLQHNGSQVLARDPEALEYAVATSVAAKARIVAEDERETTG
ARALLNLGHTFGHALEAQMGFSDRLLHGEGVAAGMVLAARYSARRGDLGDSDASLITRAVEGAGLPSEIAALDMDTDGAE
LVTHMLHDKKMDAGTLPFLLLRSIGAAYLAKDVDLKDVAAFLDEQLQAH
>Mature_368_residues
AVIPVELAGRGYQVHVGRDVIDRLGSLAAPFVRKSRLVVVADTNAWRHHGERFSQAAHSAGWAIALYEVPPGEGSKSWAS
LQRLTDWLLEQEVERGNHVFALGGGVVGDLTGFACAILKRGCGFIQIPTTLLAQVDSSVGGKTAINSSTGKNLIGAFHQP
SLVLADLATLDTLPEREMRSGYAEVLKYGVLGDRAFFDWLQHNGSQVLARDPEALEYAVATSVAAKARIVAEDERETTGA
RALLNLGHTFGHALEAQMGFSDRLLHGEGVAAGMVLAARYSARRGDLGDSDASLITRAVEGAGLPSEIAALDMDTDGAEL
VTHMLHDKKMDAGTLPFLLLRSIGAAYLAKDVDLKDVAAFLDEQLQAH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=347, Percent_Identity=44.6685878962536, Blast_Score=245, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6320332, Length=396, Percent_Identity=34.3434343434343, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39399; Mature: 39268

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIPVELAGRGYQVHVGRDVIDRLGSLAAPFVRKSRLVVVADTNAWRHHGERFSQAAHS
CEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHC
AGWAIALYEVPPGEGSKSWASLQRLTDWLLEQEVERGNHVFALGGGVVGDLTGFACAILK
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
RGCGFIQIPTTLLAQVDSSVGGKTAINSSTGKNLIGAFHQPSLVLADLATLDTLPEREMR
CCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHH
SGYAEVLKYGVLGDRAFFDWLQHNGSQVLARDPEALEYAVATSVAAKARIVAEDERETTG
HHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHEEECCCHHHHH
ARALLNLGHTFGHALEAQMGFSDRLLHGEGVAAGMVLAARYSARRGDLGDSDASLITRAV
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
EGAGLPSEIAALDMDTDGAELVTHMLHDKKMDAGTLPFLLLRSIGAAYLAKDVDLKDVAA
HCCCCCHHHHEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
FLDEQLQAH
HHHHHHHCC
>Mature Secondary Structure 
AVIPVELAGRGYQVHVGRDVIDRLGSLAAPFVRKSRLVVVADTNAWRHHGERFSQAAHS
EEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHC
AGWAIALYEVPPGEGSKSWASLQRLTDWLLEQEVERGNHVFALGGGVVGDLTGFACAILK
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
RGCGFIQIPTTLLAQVDSSVGGKTAINSSTGKNLIGAFHQPSLVLADLATLDTLPEREMR
CCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHH
SGYAEVLKYGVLGDRAFFDWLQHNGSQVLARDPEALEYAVATSVAAKARIVAEDERETTG
HHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHEEECCCHHHHH
ARALLNLGHTFGHALEAQMGFSDRLLHGEGVAAGMVLAARYSARRGDLGDSDASLITRAV
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
EGAGLPSEIAALDMDTDGAELVTHMLHDKKMDAGTLPFLLLRSIGAAYLAKDVDLKDVAA
HCCCCCHHHHEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
FLDEQLQAH
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA