Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 85373821

GI number: 85373821

Start: 1022919

End: 1023488

Strand: Reverse

Name: aroK [H]

Synonym: ELI_04970

Alternate gene names: 85373821

Gene position: 1023488-1022919 (Counterclockwise)

Preceding gene: 85373827

Following gene: 85373820

Centisome position: 33.53

GC content: 62.46

Gene sequence:

>570_bases
ATGCATCACGACGCATCCTCCCCCGGCGACGGCGCTATTGCCGCCATGGCCCACCGGGTCACGCGGCCGGTGGTATTGGT
CGGACTGATGGGGGTAGGCAAATCGACGGTCGGTCGGCGGCTGGCCAAGCTTATGCAGCGCGATTTCATCGATGCCGACG
ACGAGATCGAAGAGGCAGCGCAAATGTCGATCTCGGAAATCTTCAGTGCCTTTGGCGAGGACTATTTTCGTGACGGAGAG
CGGAGGGTTATCGCGCGTCTTATGGGAGAGGGTCACGGCGTTATTGCGACCGGCGGCGGTGCCTTCGTCAACGCCGAAAC
CCGCGCGCTGATCCTCGACCAGGGGATCGCCGTGTGGATCGATTGCGACATACCCACGCTGGTCGAACGAACCGGTCGCC
GCGATACCCGGCCACTTCTCCGTCAGGGCGATCCCGAGGAGATCCTGGCCCGTCTTCATCGTGAGCGCGAGAAGTTCTAT
TCGCAGGCTCCGATCCGGGTAAGCAGCGGTGACGGACCGCACTTGCGGACCGCAACGCAAATCCTGGAGGCAATCGACCG
ATGGCTGTGA

Upstream 100 bases:

>100_bases
AAGCCCGTGCCCCACCGCCGTCGACGCATAGCCAAACCCGTTTCCTGCAATAGTTAGCCTTTATTGCTTTCGCCCTAGCC
CATCTCTAGGCCCAGCGGCA

Downstream 100 bases:

>100_bases
TTCCGGTCGAACTGGCAGGGCGCGGATACCAAGTCCACGTCGGACGCGACGTGATCGATCGGCTCGGGTCGCTGGCCGCG
CCCTTTGTGCGAAAATCGCG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MHHDASSPGDGAIAAMAHRVTRPVVLVGLMGVGKSTVGRRLAKLMQRDFIDADDEIEEAAQMSISEIFSAFGEDYFRDGE
RRVIARLMGEGHGVIATGGGAFVNAETRALILDQGIAVWIDCDIPTLVERTGRRDTRPLLRQGDPEEILARLHREREKFY
SQAPIRVSSGDGPHLRTATQILEAIDRWL

Sequences:

>Translated_189_residues
MHHDASSPGDGAIAAMAHRVTRPVVLVGLMGVGKSTVGRRLAKLMQRDFIDADDEIEEAAQMSISEIFSAFGEDYFRDGE
RRVIARLMGEGHGVIATGGGAFVNAETRALILDQGIAVWIDCDIPTLVERTGRRDTRPLLRQGDPEEILARLHREREKFY
SQAPIRVSSGDGPHLRTATQILEAIDRWL
>Mature_189_residues
MHHDASSPGDGAIAAMAHRVTRPVVLVGLMGVGKSTVGRRLAKLMQRDFIDADDEIEEAAQMSISEIFSAFGEDYFRDGE
RRVIARLMGEGHGVIATGGGAFVNAETRALILDQGIAVWIDCDIPTLVERTGRRDTRPLLRQGDPEEILARLHREREKFY
SQAPIRVSSGDGPHLRTATQILEAIDRWL

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=167, Percent_Identity=36.5269461077844, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786587, Length=144, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20858; Mature: 20858

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHDASSPGDGAIAAMAHRVTRPVVLVGLMGVGKSTVGRRLAKLMQRDFIDADDEIEEAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
QMSISEIFSAFGEDYFRDGERRVIARLMGEGHGVIATGGGAFVNAETRALILDQGIAVWI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCEEECCCCCEEEEECCEEEEE
DCDIPTLVERTGRRDTRPLLRQGDPEEILARLHREREKFYSQAPIRVSSGDGPHLRTATQ
ECCCHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHH
ILEAIDRWL
HHHHHHHCC
>Mature Secondary Structure
MHHDASSPGDGAIAAMAHRVTRPVVLVGLMGVGKSTVGRRLAKLMQRDFIDADDEIEEAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
QMSISEIFSAFGEDYFRDGERRVIARLMGEGHGVIATGGGAFVNAETRALILDQGIAVWI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCEEECCCCCEEEEECCEEEEE
DCDIPTLVERTGRRDTRPLLRQGDPEEILARLHREREKFYSQAPIRVSSGDGPHLRTATQ
ECCCHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHH
ILEAIDRWL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA