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The map label for this gene is trxB [H]

Identifier: 85373767

GI number: 85373767

Start: 972522

End: 973511

Strand: Direct

Name: trxB [H]

Synonym: ELI_04700

Alternate gene names: 85373767

Gene position: 972522-973511 (Clockwise)

Preceding gene: 85373766

Following gene: 85373771

Centisome position: 31.86

GC content: 62.63

Gene sequence:

>990_bases
ATGACTACCCATCGCACCAAGATGCTCATCATCGGTTCCGGCCCGGCCGGTTATTCCGCCGCGATCTATGGCGCGCGCGC
GATGATGGAACCGATCGTGGTGCAGGGTATCCAGCCCGGCGGCCAGCTGACCATCACTACCGATGTCGAGAACTATCCCG
GCTTCGAAGAGGTGATCCAGGGGCCGTGGCTGATGGAGCAGATGCAGAAGCAGGCCGAGCATGTCGGCACGCGCATGATG
TGGGATACCATCGTCGACGTCGATATCGAGAACGGCTCGCCCTTCCGCGCCGTCGGCGACAGCGGCGATGAATATATCGG
CGACGTGCTGATCATCGCCACCGGCGCGCAGGCCAAGTGGCTCGGCGTGCCCGGCGAGCAGGAACTCGGCGGCAAGGGCG
TTTCCGCCTGTGCGACCTGCGACGGGTTCTTCTATCGCGGCAAGAAAGTCGCGGTCATCGGCGGTGGCAATACCGCGGTC
GAGGAAGCGCTCTATCTTACCAATCATTCCGACGACGTGACGCTGATCCATCGCCGCGACGAGCTGCGCAGCGAGAAAAT
CCTGCAGGAGCGGCTGTTCAAGTCGGACAAGATCTCGACCCTGTGGAACAAAACCGTCGAGAGCTTCGAGGCGGGTGAAG
ACGGCATGCTGAGCCATCTCGTGCTCAAGGACACGCAGACCGGCGAATTGTCCAACCTCGAAGTCGACGGAGCCTTCGTC
GCGATCGGCCACGCGCCTGCGACCGAATTGTTCAAAGGCAAGCTGCCGATGGACGAAACCGGCTATTTGCTGGTCGAGCC
GGGCACGCCCAAGACCGCGATTCCGGGCGTATTTGCCGCCGGCGACGTGATGGATCACATCTATCGCCAGGCGGTCACCG
CTGCGGGTGTGGGCTGCATGGCCGCGCTCGATGCAGAACGCTTCCTCGCAAACCTGGAAATCGACATCGACGGCCATGTC
CACGCGCCTCAAACCGAGGCGGCGGAGTGA

Upstream 100 bases:

>100_bases
TGGAAAGCTAACCAGATCGGCTGGACCGGCGCAGGAGCAGCCCGCAGAGAGGGCTTTCGGCTCGCGGCAAGAGACCGCGC
CCCAGACAGGACACGAGAAA

Downstream 100 bases:

>100_bases
ACTTCGGGCGAGCCCCAGCGTAGGCTGGGGCCTCCATCAGCCTGGCATCGCGCCAGTGGTATGAGGTCCCAGCCTCCGCT
GGGACTCCCGCGTTTCTTAC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTTHRTKMLIIGSGPAGYSAAIYGARAMMEPIVVQGIQPGGQLTITTDVENYPGFEEVIQGPWLMEQMQKQAEHVGTRMM
WDTIVDVDIENGSPFRAVGDSGDEYIGDVLIIATGAQAKWLGVPGEQELGGKGVSACATCDGFFYRGKKVAVIGGGNTAV
EEALYLTNHSDDVTLIHRRDELRSEKILQERLFKSDKISTLWNKTVESFEAGEDGMLSHLVLKDTQTGELSNLEVDGAFV
AIGHAPATELFKGKLPMDETGYLLVEPGTPKTAIPGVFAAGDVMDHIYRQAVTAAGVGCMAALDAERFLANLEIDIDGHV
HAPQTEAAE

Sequences:

>Translated_329_residues
MTTHRTKMLIIGSGPAGYSAAIYGARAMMEPIVVQGIQPGGQLTITTDVENYPGFEEVIQGPWLMEQMQKQAEHVGTRMM
WDTIVDVDIENGSPFRAVGDSGDEYIGDVLIIATGAQAKWLGVPGEQELGGKGVSACATCDGFFYRGKKVAVIGGGNTAV
EEALYLTNHSDDVTLIHRRDELRSEKILQERLFKSDKISTLWNKTVESFEAGEDGMLSHLVLKDTQTGELSNLEVDGAFV
AIGHAPATELFKGKLPMDETGYLLVEPGTPKTAIPGVFAAGDVMDHIYRQAVTAAGVGCMAALDAERFLANLEIDIDGHV
HAPQTEAAE
>Mature_328_residues
TTHRTKMLIIGSGPAGYSAAIYGARAMMEPIVVQGIQPGGQLTITTDVENYPGFEEVIQGPWLMEQMQKQAEHVGTRMMW
DTIVDVDIENGSPFRAVGDSGDEYIGDVLIIATGAQAKWLGVPGEQELGGKGVSACATCDGFFYRGKKVAVIGGGNTAVE
EALYLTNHSDDVTLIHRRDELRSEKILQERLFKSDKISTLWNKTVESFEAGEDGMLSHLVLKDTQTGELSNLEVDGAFVA
IGHAPATELFKGKLPMDETGYLLVEPGTPKTAIPGVFAAGDVMDHIYRQAVTAAGVGCMAALDAERFLANLEIDIDGHVH
APQTEAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=55.1724137931034, Blast_Score=339, Evalue=1e-94,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=32.3529411764706, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=46.8553459119497, Blast_Score=281, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=318, Percent_Identity=45.9119496855346, Blast_Score=278, Evalue=9e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35368; Mature: 35237

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHRTKMLIIGSGPAGYSAAIYGARAMMEPIVVQGIQPGGQLTITTDVENYPGFEEVIQ
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHC
GPWLMEQMQKQAEHVGTRMMWDTIVDVDIENGSPFRAVGDSGDEYIGDVLIIATGAQAKW
CCHHHHHHHHHHHHHCHHEEEEEEEEEEECCCCCCEEECCCCCHHHCEEEEEEECCCEEE
LGVPGEQELGGKGVSACATCDGFFYRGKKVAVIGGGNTAVEEALYLTNHSDDVTLIHRRD
ECCCCCHHCCCCCCCHHEECCCCEECCCEEEEEECCCHHHHHEEEEECCCCCEEEEECHH
ELRSEKILQERLFKSDKISTLWNKTVESFEAGEDGMLSHLVLKDTQTGELSNLEVDGAFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEECCEEE
AIGHAPATELFKGKLPMDETGYLLVEPGTPKTAIPGVFAAGDVMDHIYRQAVTAAGVGCM
EECCCCHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
AALDAERFLANLEIDIDGHVHAPQTEAAE
HHHHHHHHHEEEEEEECCCEECCCCCCCC
>Mature Secondary Structure 
TTHRTKMLIIGSGPAGYSAAIYGARAMMEPIVVQGIQPGGQLTITTDVENYPGFEEVIQ
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHC
GPWLMEQMQKQAEHVGTRMMWDTIVDVDIENGSPFRAVGDSGDEYIGDVLIIATGAQAKW
CCHHHHHHHHHHHHHCHHEEEEEEEEEEECCCCCCEEECCCCCHHHCEEEEEEECCCEEE
LGVPGEQELGGKGVSACATCDGFFYRGKKVAVIGGGNTAVEEALYLTNHSDDVTLIHRRD
ECCCCCHHCCCCCCCHHEECCCCEECCCEEEEEECCCHHHHHEEEEECCCCCEEEEECHH
ELRSEKILQERLFKSDKISTLWNKTVESFEAGEDGMLSHLVLKDTQTGELSNLEVDGAFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEECCEEE
AIGHAPATELFKGKLPMDETGYLLVEPGTPKTAIPGVFAAGDVMDHIYRQAVTAAGVGCM
EECCCCHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
AALDAERFLANLEIDIDGHVHAPQTEAAE
HHHHHHHHHEEEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA