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The map label for this gene is ccmC [H]

Identifier: 85373598

GI number: 85373598

Start: 797275

End: 797997

Strand: Direct

Name: ccmC [H]

Synonym: ELI_03855

Alternate gene names: 85373598

Gene position: 797275-797997 (Clockwise)

Preceding gene: 85373597

Following gene: 85373599

Centisome position: 26.12

GC content: 66.94

Gene sequence:

>723_bases
ATGCACGCTTTCGCCAATCCCAAACGCTTCCTGTCGCTCGCCGGCTGGCTCACGCCGCTATTGCTGGTGAGCGGTCTGGT
GCTCGCCGCAGGTTCGCTGTGGTGGGGGCTGACGCAGGTGCCGCCCGATCGGCTGATGGGCGAAACGGTGCGCATCCTGT
TCCTGCACGTGCCCGCTGCCTGGCTCGGCATGGGGGGATGGACCGCAATCGCGGTGTCGAGCCTCGTCTACCTCGTCTGG
CGCCACCCGCTCGCGGCGATCGCCGCGCAGGCGGCGGCATGGCCGGGCATTGTGTTTACTGCGATCTGCCTCGCGACGGG
GTCGATCTGGGGCCGCCCGACATGGGGGACCTGGTGGGTGTGGGACGGGCGGCTGACCAGCATGCTAGTGCTGCTGTTCC
TCTATGCAGGTTATCTCGCACTGGCGCAGGCGGCCGAGCGTGAGGGCGTGTCCGCACGGATTCCCGCGATCTTCGGCCTT
GTCGGCGCCGTCAATATCCCGATCATCAACCGTTCGGTCGTGTGGTGGAATTCGCTGCACCAGCCACCCTCGATCACCGT
CGGGAAGAGCGCGATTGCGCCTGAGTTCCTGTGGCCGCTGCTCATCGCAGTCGTCGGTTTTTCGTTGATCTTCGGCGGCG
TCGTGCTGGCGCGGATGCGGGCGATTCTCGCCGATGTCCAGACCGAGGCCCGGCTGCGGCGCAAGGCAATGGAGGCGGCG
TGA

Upstream 100 bases:

>100_bases
GACCGCATGGCCCAGAAGCTCATCGGGCGGTGACGAATAGGCCTTCGGTCTCGCTTGCAGGGGCCTGCCCGCGCGACTAG
ATTGCAACGCGACACGTCTC

Downstream 100 bases:

>100_bases
TGCGCGAGGGGCTCGACCAATGGGACTTCGTGATCGCGGCCTATGCGGTGGGCGTTCTCGGCACGTTGGCTATGGTGGCG
TGGAGCTGGATTTCGATGAA

Product: ABC-type transport system heme exporter

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MHAFANPKRFLSLAGWLTPLLLVSGLVLAAGSLWWGLTQVPPDRLMGETVRILFLHVPAAWLGMGGWTAIAVSSLVYLVW
RHPLAAIAAQAAAWPGIVFTAICLATGSIWGRPTWGTWWVWDGRLTSMLVLLFLYAGYLALAQAAEREGVSARIPAIFGL
VGAVNIPIINRSVVWWNSLHQPPSITVGKSAIAPEFLWPLLIAVVGFSLIFGGVVLARMRAILADVQTEARLRRKAMEAA

Sequences:

>Translated_240_residues
MHAFANPKRFLSLAGWLTPLLLVSGLVLAAGSLWWGLTQVPPDRLMGETVRILFLHVPAAWLGMGGWTAIAVSSLVYLVW
RHPLAAIAAQAAAWPGIVFTAICLATGSIWGRPTWGTWWVWDGRLTSMLVLLFLYAGYLALAQAAEREGVSARIPAIFGL
VGAVNIPIINRSVVWWNSLHQPPSITVGKSAIAPEFLWPLLIAVVGFSLIFGGVVLARMRAILADVQTEARLRRKAMEAA
>Mature_240_residues
MHAFANPKRFLSLAGWLTPLLLVSGLVLAAGSLWWGLTQVPPDRLMGETVRILFLHVPAAWLGMGGWTAIAVSSLVYLVW
RHPLAAIAAQAAAWPGIVFTAICLATGSIWGRPTWGTWWVWDGRLTSMLVLLFLYAGYLALAQAAEREGVSARIPAIFGL
VGAVNIPIINRSVVWWNSLHQPPSITVGKSAIAPEFLWPLLIAVVGFSLIFGGVVLARMRAILADVQTEARLRRKAMEAA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=223, Percent_Identity=43.4977578475336, Blast_Score=171, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26052; Mature: 26052

Theoretical pI: Translated: 11.32; Mature: 11.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAFANPKRFLSLAGWLTPLLLVSGLVLAAGSLWWGLTQVPPDRLMGETVRILFLHVPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WLGMGGWTAIAVSSLVYLVWRHPLAAIAAQAAAWPGIVFTAICLATGSIWGRPTWGTWWV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEE
WDGRLTSMLVLLFLYAGYLALAQAAEREGVSARIPAIFGLVGAVNIPIINRSVVWWNSLH
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCEEEHHCCC
QPPSITVGKSAIAPEFLWPLLIAVVGFSLIFGGVVLARMRAILADVQTEARLRRKAMEAA
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHAFANPKRFLSLAGWLTPLLLVSGLVLAAGSLWWGLTQVPPDRLMGETVRILFLHVPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WLGMGGWTAIAVSSLVYLVWRHPLAAIAAQAAAWPGIVFTAICLATGSIWGRPTWGTWWV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEE
WDGRLTSMLVLLFLYAGYLALAQAAEREGVSARIPAIFGLVGAVNIPIINRSVVWWNSLH
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCEEEHHCCC
QPPSITVGKSAIAPEFLWPLLIAVVGFSLIFGGVVLARMRAILADVQTEARLRRKAMEAA
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]