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The map label for this gene is fabH [H]

Identifier: 85373576

GI number: 85373576

Start: 776852

End: 777997

Strand: Direct

Name: fabH [H]

Synonym: ELI_03745

Alternate gene names: 85373576

Gene position: 776852-777997 (Clockwise)

Preceding gene: 85373575

Following gene: 85373577

Centisome position: 25.45

GC content: 62.04

Gene sequence:

>1146_bases
ATGAACACAATAGCCAGTGAAAACACCGGTCGCCCCGTCATTTCCTCAACCGGGCTTTTCACCCCAGAGGAATCGATTTC
CAACGAAGAACTGGTCGAAGCCTTCAACGCTTTCGTCGACCGCCATAATGCGGAACATGCCGATGCGATTGCGGCGGGCG
AGGCGGAAGAATTGCAGCATAGCTCCGTCGAATTCATCGAGAAGGCGAGCGGGATCAAGTCGCGTCACGTGATGAACAAG
GCGCCGATCATCGATCCGGCCATCATGGAGCCGCGCCACCGCGAGCGCAGCAATGACGAACTGTCGCTGATGGCGGAAAT
CGGCGTTGCCGCATCCAGGCAGGCGCTGGAGCGGGCGGGGCGCGACGTGGCCGATGTCGATGCCGTGCTGTGCGCCGCTT
CGAACATGGAGCGGCCCTATCCGGCGATGGCGGTCGAAATCCAGCAGGCGCTCGGGATCGACGGGTTCGGCTTCGATATG
AATGTCGCCTGCTCGTCGGCGACTTTCGGTATCCAGACCGCGGCGGACTATGTCCGCGCAGGCAACGCCAAGAGCGTGCT
GGTGGTGAGTCCCGAGATCACGTCGGGCCATCTCAACTGGCGCGACCGCGACAGTCACTTCATCTTCGGCGATGTCGCAA
CCGCCGTGCTGGTAGAGGATGCGAGCATCGCGCCGGCCGAGCATTGGGACATCCTCGGTACGAAGCTCAAGACGGTGTTC
TCCAACAACATCCGCAACAATTTCGGCTTCCTCAACCGCGCCTGTCCTGAAAGCCAGGGCAGCCCAGACAAGCTGTTCGT
CCAGGAAGGACGAAAGGTCTTCAAGGAAGTCGTGCCGATGGTTGCACACATGATCGTCGAGGAAGCGGAGCGGCTCGGCA
TCGATCCCAAGGCTCTGCGCCGGATGTGGCTGCACCAGGCCAATGCCGGGATGAACCGGCTGATCGCGCACAAAGTGCTG
GGGCACGAGGCGGAAGAGGACGAGAGCCCGACGGTTCTCGATACCTATGGCAACACGTCGAGCGCGGGCTCGATCATCGC
CTTCCACCAGCACTCGGGCGACCTCGCTCCGGGCGATACCGGGCTGATCTGCAGCTTCGGCGCGGGCTATTCCGCCGGGA
CGGTTTTCGTTCGCAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
AACGGCAACGGCCGCTCGCTCCTTCGGGATCGGGCGGCCGTTTCCTTTTGTGCAAGCAAACCGCTTGCCCGGTGCATCCC
GGACAATTAGTCAGGCGCGC

Downstream 100 bases:

>100_bases
TGCCCTGCGCCGACAAGTTGTTTTCCTTGTCGCCCCCGTTTCCAGCACCTAGGTGAGGCCCCATGGCAAATGATTTGCTC
GACAATAAGGGTCGCGGCGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNTIASENTGRPVISSTGLFTPEESISNEELVEAFNAFVDRHNAEHADAIAAGEAEELQHSSVEFIEKASGIKSRHVMNK
APIIDPAIMEPRHRERSNDELSLMAEIGVAASRQALERAGRDVADVDAVLCAASNMERPYPAMAVEIQQALGIDGFGFDM
NVACSSATFGIQTAADYVRAGNAKSVLVVSPEITSGHLNWRDRDSHFIFGDVATAVLVEDASIAPAEHWDILGTKLKTVF
SNNIRNNFGFLNRACPESQGSPDKLFVQEGRKVFKEVVPMVAHMIVEEAERLGIDPKALRRMWLHQANAGMNRLIAHKVL
GHEAEEDESPTVLDTYGNTSSAGSIIAFHQHSGDLAPGDTGLICSFGAGYSAGTVFVRKAA

Sequences:

>Translated_381_residues
MNTIASENTGRPVISSTGLFTPEESISNEELVEAFNAFVDRHNAEHADAIAAGEAEELQHSSVEFIEKASGIKSRHVMNK
APIIDPAIMEPRHRERSNDELSLMAEIGVAASRQALERAGRDVADVDAVLCAASNMERPYPAMAVEIQQALGIDGFGFDM
NVACSSATFGIQTAADYVRAGNAKSVLVVSPEITSGHLNWRDRDSHFIFGDVATAVLVEDASIAPAEHWDILGTKLKTVF
SNNIRNNFGFLNRACPESQGSPDKLFVQEGRKVFKEVVPMVAHMIVEEAERLGIDPKALRRMWLHQANAGMNRLIAHKVL
GHEAEEDESPTVLDTYGNTSSAGSIIAFHQHSGDLAPGDTGLICSFGAGYSAGTVFVRKAA
>Mature_381_residues
MNTIASENTGRPVISSTGLFTPEESISNEELVEAFNAFVDRHNAEHADAIAAGEAEELQHSSVEFIEKASGIKSRHVMNK
APIIDPAIMEPRHRERSNDELSLMAEIGVAASRQALERAGRDVADVDAVLCAASNMERPYPAMAVEIQQALGIDGFGFDM
NVACSSATFGIQTAADYVRAGNAKSVLVVSPEITSGHLNWRDRDSHFIFGDVATAVLVEDASIAPAEHWDILGTKLKTVF
SNNIRNNFGFLNRACPESQGSPDKLFVQEGRKVFKEVVPMVAHMIVEEAERLGIDPKALRRMWLHQANAGMNRLIAHKVL
GHEAEEDESPTVLDTYGNTSSAGSIIAFHQHSGDLAPGDTGLICSFGAGYSAGTVFVRKAA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=328, Percent_Identity=28.6585365853659, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41126; Mature: 41126

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIASENTGRPVISSTGLFTPEESISNEELVEAFNAFVDRHNAEHADAIAAGEAEELQH
CCCCCCCCCCCCEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
SSVEFIEKASGIKSRHVMNKAPIIDPAIMEPRHRERSNDELSLMAEIGVAASRQALERAG
HHHHHHHHHCCCHHHHHHCCCCCCCHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
RDVADVDAVLCAASNMERPYPAMAVEIQQALGIDGFGFDMNVACSSATFGIQTAADYVRA
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHC
GNAKSVLVVSPEITSGHLNWRDRDSHFIFGDVATAVLVEDASIAPAEHWDILGTKLKTVF
CCCCEEEEECCCCCCCCCCCCCCCCCEEEHHHHEEHEEECCCCCCHHHHHHHHHHHHHHH
SNNIRNNFGFLNRACPESQGSPDKLFVQEGRKVFKEVVPMVAHMIVEEAERLGIDPKALR
HHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RMWLHQANAGMNRLIAHKVLGHEAEEDESPTVLDTYGNTSSAGSIIAFHQHSGDLAPGDT
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCC
GLICSFGAGYSAGTVFVRKAA
CEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure
MNTIASENTGRPVISSTGLFTPEESISNEELVEAFNAFVDRHNAEHADAIAAGEAEELQH
CCCCCCCCCCCCEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
SSVEFIEKASGIKSRHVMNKAPIIDPAIMEPRHRERSNDELSLMAEIGVAASRQALERAG
HHHHHHHHHCCCHHHHHHCCCCCCCHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
RDVADVDAVLCAASNMERPYPAMAVEIQQALGIDGFGFDMNVACSSATFGIQTAADYVRA
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHC
GNAKSVLVVSPEITSGHLNWRDRDSHFIFGDVATAVLVEDASIAPAEHWDILGTKLKTVF
CCCCEEEEECCCCCCCCCCCCCCCCCEEEHHHHEEHEEECCCCCCHHHHHHHHHHHHHHH
SNNIRNNFGFLNRACPESQGSPDKLFVQEGRKVFKEVVPMVAHMIVEEAERLGIDPKALR
HHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RMWLHQANAGMNRLIAHKVLGHEAEEDESPTVLDTYGNTSSAGSIIAFHQHSGDLAPGDT
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCC
GLICSFGAGYSAGTVFVRKAA
CEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA