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The map label for this gene is hfaC [H]

Identifier: 85373552

GI number: 85373552

Start: 748111

End: 749910

Strand: Reverse

Name: hfaC [H]

Synonym: ELI_03625

Alternate gene names: 85373552

Gene position: 749910-748111 (Counterclockwise)

Preceding gene: 85373553

Following gene: 85373551

Centisome position: 24.57

GC content: 64.33

Gene sequence:

>1800_bases
ATGGCACAGCCACCGATCTTGAGTTGGGAAGGTCTCGGACTGCAACAGGGCGGGCGCTGGCTGCTGGGCGGCCCTGACCG
CGAGGACATCGACCTTCATATCGGTCCGCGTGACCGGCTGGCGCTGATCGGCCGCAACGGCGCGGGCAAGACCACGCTGT
TCCGCCTGATCAGTGACCAGATCGAAGCCGATCGCGGACAGCGAAAAGTCAAGCAGGGCACGCGCATCGTGGTGCTGGAA
CAGGATCCGGATTTTGCCGGGCACGCGACGCTGATGGACTGGGCGTTGGCTGGCGAGAACGCGCCGCAGCAGCACGAGGT
CGAGTCGATTGCCGGGCAGCTCGGCATCGATATGACCACATCTGCGGAAGGCGCCAGTGGCGGTGAGCGACGCCGCGCGG
CGATCTCTCGCGCATTGGCGCAGGACCCCGACCTGCTGTTGATGGACGAGCCGACAAACCACCTCGACCTGTCGGCCATT
GAATGGCTGGAAGGCTGGCTGGATCGCTACAAGGGCGCGTTCATCGTCATCAGCCACGACCGGACCTTCCTGAAGCGGCT
GACGCGCGCGACGTTTTGGCTGGACCGGGGAATCATCCGCCGCAAGGAAGTGGGCTTCGGCGGCTACGAGGCGTGGGAAG
AGCAGGTCTATGCCGAGGAAGCACGCGCCGCCGAAAAGCTCGATGCCAGGCTGAAGCTCGAAGCGCACTGGCTCGAACGC
GGCGTGACCGCCCGGCGCAAGCGCAACCAGGGGCGGCTCGAAGCACTGTGGAAGATGCGCGCAGCGCGGGCGGCGATGAT
CGACACCGGCGGCACGGCCAAGCTCAAGCTGGCGGTGGAGGAGGACTTCAAGTCCAAGTCCGTGATCGTCGCAGAGAACA
TCACCAAAACCTATGACGGTCGTACCATCATTCGGCCCTTCAGCCTTCGCATCCAGCGCGGCGACCGGATCGGGATCGTC
GGTTCCAATGGTGCGGGCAAAACGACGCTGCTCAAGATGCTGACCGGCGAACTGGAGCCGGATAGCGGCACGGTCGAGAT
CAGCAAGAAGCTGAGCGGTGTGATGATCGACCAGCAGCGCAGCCTTATGGAGCCCGACCGCACCGTGCGGCAGGTGCTGG
CCGAAGGCGGCGACTGGATCGATGTGCGCGGCAATCGCAAGCATGTGCAGGCGCATCTCAAGGACTTCCTGTTCGACCCC
AGGATCGTCGATACCAAGGTCGGCATCCTTTCGGGCGGCGAGCGATCGCGGCTGCTGCTGGCGCGCGAGTTTGCCCGCAA
GTCCAACCTGCTCGTGCTCGACGAGCCGACAAACGATCTCGACCTCGAGACGCTCGACCTGCTGCAGGAAGTGATCGCGG
ATTACGAGGGCACCGTGCTGATCGTCAGCCACGACCGTGACTTCCTCGACCGTACGGTCACTCTGACGCTGGGCCTCGAC
GGTAGCGGCAAGGTCGATGTCGTCGCCGGCGGCTATGAGGACTGGGAAGCCAAGCGCAGCACGCGCAAGGTGGGCAAGAC
GAAGGAGGCTGCCAAGCCGAGCGCCCCGCCCCCGCCTCCGCCACCCAAATCCACCAAGCTCTCTTACAAGGACCAGCGCG
ACTACGAGATTTTGCCTGCGAGGATCGAGGAGCTGGAGGCTGCCATAGTCAAGGGTGAGGCGATCCTCTCCGATCCAGAC
CTCTACAGCAGCGACCCACAGCGCTTTGCCGATATTTCCAAGGGCGTCGAAAATGCACGGAGCGAGAAGGACGCGGCCGA
GGAGCGCTGGCTGGAGCTCGCGGAACTGGTCGAGGGATGA

Upstream 100 bases:

>100_bases
GCTTGCCGATGTCGCGCAAATGGTCGAGGCGCAGAAAGCCGCTCGCTAGCCCTATTGCTCGCTTGCGGGCGCGCGCGCCC
TCGCCTACCTGCCGCCGCCT

Downstream 100 bases:

>100_bases
GCCTGCAAGCCGAGATTGCGGCGTGCCGCATCTGCGCTGACAAGCTGGCTCACGATCCGCGACCGGTGGCCACATTCAGC
TCCACGGCGCGTTTGCTGAT

Product: ABC transporter

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MAQPPILSWEGLGLQQGGRWLLGGPDREDIDLHIGPRDRLALIGRNGAGKTTLFRLISDQIEADRGQRKVKQGTRIVVLE
QDPDFAGHATLMDWALAGENAPQQHEVESIAGQLGIDMTTSAEGASGGERRRAAISRALAQDPDLLLMDEPTNHLDLSAI
EWLEGWLDRYKGAFIVISHDRTFLKRLTRATFWLDRGIIRRKEVGFGGYEAWEEQVYAEEARAAEKLDARLKLEAHWLER
GVTARRKRNQGRLEALWKMRAARAAMIDTGGTAKLKLAVEEDFKSKSVIVAENITKTYDGRTIIRPFSLRIQRGDRIGIV
GSNGAGKTTLLKMLTGELEPDSGTVEISKKLSGVMIDQQRSLMEPDRTVRQVLAEGGDWIDVRGNRKHVQAHLKDFLFDP
RIVDTKVGILSGGERSRLLLAREFARKSNLLVLDEPTNDLDLETLDLLQEVIADYEGTVLIVSHDRDFLDRTVTLTLGLD
GSGKVDVVAGGYEDWEAKRSTRKVGKTKEAAKPSAPPPPPPPKSTKLSYKDQRDYEILPARIEELEAAIVKGEAILSDPD
LYSSDPQRFADISKGVENARSEKDAAEERWLELAELVEG

Sequences:

>Translated_599_residues
MAQPPILSWEGLGLQQGGRWLLGGPDREDIDLHIGPRDRLALIGRNGAGKTTLFRLISDQIEADRGQRKVKQGTRIVVLE
QDPDFAGHATLMDWALAGENAPQQHEVESIAGQLGIDMTTSAEGASGGERRRAAISRALAQDPDLLLMDEPTNHLDLSAI
EWLEGWLDRYKGAFIVISHDRTFLKRLTRATFWLDRGIIRRKEVGFGGYEAWEEQVYAEEARAAEKLDARLKLEAHWLER
GVTARRKRNQGRLEALWKMRAARAAMIDTGGTAKLKLAVEEDFKSKSVIVAENITKTYDGRTIIRPFSLRIQRGDRIGIV
GSNGAGKTTLLKMLTGELEPDSGTVEISKKLSGVMIDQQRSLMEPDRTVRQVLAEGGDWIDVRGNRKHVQAHLKDFLFDP
RIVDTKVGILSGGERSRLLLAREFARKSNLLVLDEPTNDLDLETLDLLQEVIADYEGTVLIVSHDRDFLDRTVTLTLGLD
GSGKVDVVAGGYEDWEAKRSTRKVGKTKEAAKPSAPPPPPPPKSTKLSYKDQRDYEILPARIEELEAAIVKGEAILSDPD
LYSSDPQRFADISKGVENARSEKDAAEERWLELAELVEG
>Mature_598_residues
AQPPILSWEGLGLQQGGRWLLGGPDREDIDLHIGPRDRLALIGRNGAGKTTLFRLISDQIEADRGQRKVKQGTRIVVLEQ
DPDFAGHATLMDWALAGENAPQQHEVESIAGQLGIDMTTSAEGASGGERRRAAISRALAQDPDLLLMDEPTNHLDLSAIE
WLEGWLDRYKGAFIVISHDRTFLKRLTRATFWLDRGIIRRKEVGFGGYEAWEEQVYAEEARAAEKLDARLKLEAHWLERG
VTARRKRNQGRLEALWKMRAARAAMIDTGGTAKLKLAVEEDFKSKSVIVAENITKTYDGRTIIRPFSLRIQRGDRIGIVG
SNGAGKTTLLKMLTGELEPDSGTVEISKKLSGVMIDQQRSLMEPDRTVRQVLAEGGDWIDVRGNRKHVQAHLKDFLFDPR
IVDTKVGILSGGERSRLLLAREFARKSNLLVLDEPTNDLDLETLDLLQEVIADYEGTVLIVSHDRDFLDRTVTLTLGLDG
SGKVDVVAGGYEDWEAKRSTRKVGKTKEAAKPSAPPPPPPPKSTKLSYKDQRDYEILPARIEELEAAIVKGEAILSDPDL
YSSDPQRFADISKGVENARSEKDAAEERWLELAELVEG

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=533, Percent_Identity=28.3302063789869, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI69354671, Length=520, Percent_Identity=27.1153846153846, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI10947135, Length=520, Percent_Identity=27.1153846153846, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI10947137, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI27881506, Length=234, Percent_Identity=27.3504273504274, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI31657092, Length=205, Percent_Identity=30.2439024390244, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI90421313, Length=151, Percent_Identity=33.112582781457, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787182, Length=634, Percent_Identity=37.8548895899054, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI2367384, Length=515, Percent_Identity=31.4563106796116, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1789751, Length=656, Percent_Identity=28.6585365853659, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1787041, Length=521, Percent_Identity=28.2149712092131, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI87081791, Length=198, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788165, Length=217, Percent_Identity=30.8755760368664, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787758, Length=197, Percent_Identity=29.4416243654822, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788225, Length=224, Percent_Identity=27.6785714285714, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786345, Length=226, Percent_Identity=31.4159292035398, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081834, Length=191, Percent_Identity=30.3664921465969, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081709, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081782, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787500, Length=198, Percent_Identity=23.7373737373737, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=28.5067873303167, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789891, Length=216, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789672, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=165, Percent_Identity=28.4848484848485, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787792, Length=228, Percent_Identity=27.6315789473684, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786975, Length=203, Percent_Identity=29.064039408867, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=214, Percent_Identity=26.6355140186916, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1787029, Length=222, Percent_Identity=25.6756756756757, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=396, Percent_Identity=28.7878787878788, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17553372, Length=546, Percent_Identity=28.021978021978, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17555318, Length=413, Percent_Identity=28.3292978208232, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71988343, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=396, Percent_Identity=29.5454545454545, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320874, Length=362, Percent_Identity=27.6243093922652, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324314, Length=330, Percent_Identity=28.1818181818182, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323278, Length=330, Percent_Identity=27.5757575757576, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325030, Length=352, Percent_Identity=28.6931818181818, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24666836, Length=550, Percent_Identity=29.0909090909091, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24641342, Length=389, Percent_Identity=29.305912596401, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24642252, Length=502, Percent_Identity=28.4860557768924, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI18859989, Length=502, Percent_Identity=28.4860557768924, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI116007184, Length=191, Percent_Identity=30.3664921465969, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363262, Length=203, Percent_Identity=30.5418719211823, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221500365, Length=191, Percent_Identity=30.3664921465969, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24653245, Length=203, Percent_Identity=30.5418719211823, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17136662, Length=186, Percent_Identity=28.494623655914, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI62484234, Length=196, Percent_Identity=31.6326530612245, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 66650; Mature: 66519

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPPILSWEGLGLQQGGRWLLGGPDREDIDLHIGPRDRLALIGRNGAGKTTLFRLISDQ
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
IEADRGQRKVKQGTRIVVLEQDPDFAGHATLMDWALAGENAPQQHEVESIAGQLGIDMTT
HHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEC
SAEGASGGERRRAAISRALAQDPDLLLMDEPTNHLDLSAIEWLEGWLDRYKGAFIVISHD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECC
RTFLKRLTRATFWLDRGIIRRKEVGFGGYEAWEEQVYAEEARAAEKLDARLKLEAHWLER
HHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHC
GVTARRKRNQGRLEALWKMRAARAAMIDTGGTAKLKLAVEEDFKSKSVIVAENITKTYDG
CHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCEEEEEEEECCCCCCCEEEEECCHHHCCC
RTIIRPFSLRIQRGDRIGIVGSNGAGKTTLLKMLTGELEPDSGTVEISKKLSGVMIDQQR
CEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEHHHCCEEECCHH
SLMEPDRTVRQVLAEGGDWIDVRGNRKHVQAHLKDFLFDPRIVDTKVGILSGGERSRLLL
HHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHH
AREFARKSNLLVLDEPTNDLDLETLDLLQEVIADYEGTVLIVSHDRDFLDRTVTLTLGLD
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHCCCEEEEEEECC
GSGKVDVVAGGYEDWEAKRSTRKVGKTKEAAKPSAPPPPPPPKSTKLSYKDQRDYEILPA
CCCCEEEEECCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RIEELEAAIVKGEAILSDPDLYSSDPQRFADISKGVENARSEKDAAEERWLELAELVEG
HHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQPPILSWEGLGLQQGGRWLLGGPDREDIDLHIGPRDRLALIGRNGAGKTTLFRLISDQ
CCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
IEADRGQRKVKQGTRIVVLEQDPDFAGHATLMDWALAGENAPQQHEVESIAGQLGIDMTT
HHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEC
SAEGASGGERRRAAISRALAQDPDLLLMDEPTNHLDLSAIEWLEGWLDRYKGAFIVISHD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECC
RTFLKRLTRATFWLDRGIIRRKEVGFGGYEAWEEQVYAEEARAAEKLDARLKLEAHWLER
HHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHC
GVTARRKRNQGRLEALWKMRAARAAMIDTGGTAKLKLAVEEDFKSKSVIVAENITKTYDG
CHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCEEEEEEEECCCCCCCEEEEECCHHHCCC
RTIIRPFSLRIQRGDRIGIVGSNGAGKTTLLKMLTGELEPDSGTVEISKKLSGVMIDQQR
CEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEHHHCCEEECCHH
SLMEPDRTVRQVLAEGGDWIDVRGNRKHVQAHLKDFLFDPRIVDTKVGILSGGERSRLLL
HHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHH
AREFARKSNLLVLDEPTNDLDLETLDLLQEVIADYEGTVLIVSHDRDFLDRTVTLTLGLD
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHCCCEEEEEEECC
GSGKVDVVAGGYEDWEAKRSTRKVGKTKEAAKPSAPPPPPPPKSTKLSYKDQRDYEILPA
CCCCEEEEECCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RIEELEAAIVKGEAILSDPDLYSSDPQRFADISKGVENARSEKDAAEERWLELAELVEG
HHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]