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The map label for this gene is qor [H]

Identifier: 85373486

GI number: 85373486

Start: 695609

End: 696607

Strand: Reverse

Name: qor [H]

Synonym: ELI_03295

Alternate gene names: 85373486

Gene position: 696607-695609 (Counterclockwise)

Preceding gene: 85373487

Following gene: 85373485

Centisome position: 22.82

GC content: 62.76

Gene sequence:

>999_bases
ATGAAAGTCCTACGCACCCACGCCGTCGGAGGCCCCGAGACGCTGACACTCGACGAGGTCGAGGTCCCTACCCCGGGCAA
GGGCGAAGTGCTGGTCGATGTGAAAGCCTGCGCGATCAATTATCCCGATACGTTGATGATCCGTGACCTCTACCAGTTCA
AGCCCGAGCGTCCCTATGCGCCTGGCGGCGAAATCGCGGGAGTGGTCGAAGCGGTCGGCGAAGGCGTCGACGGCGTCTCC
GTTGGTGACAGGGTCATGGCCGGGATCGGCAATGGCGGTCTGACCGAAAAGGTCATCGTGCCCGCGGGCCGGATGTTCCC
CGTGCCCGAAGGGGTGCCTTTCGAAAAAGCCGCTTCGCTGCTGATGACTTATGGCACGACGATCCACGGCCTGAAGGATC
GCGGCCACATCAAAAAAGGCGATACCGTCCTGGTGCTGGGCGCTGCGGGCGGAGTCGGCCTGTCGGCGGTCGAACTGGCC
AAAGCCTTTGGCGCGCGCGTCGTCGCGGCTGTTTCCAGCGAGGAAAAAGGCGAAGTTGCGAGGAAAGCGGGGGCCGACGA
GGTCGTCATCTATCCGAAGGACGAGATGGACAAGGCCGCCTCCAAGGAGCTCGCAAGCGCGTTCAAGGCGGCGTGCGGCC
CGGAAGGCGCCAATATCGTCTACGATATCGTCGGCGGGCAATATTCCGAACCTGCCCTGCGCTCGATTGCCTGGGAAGGT
CGCTTCCTTGTGGTCGGCTTCCCTGCCGGGATCGCCAAGATGCCGCTTAACCTGACCCTGCTCAAGAGCTGCGACATTGC
GGGTGTCTTCTGGGGTGCCTTCACCGCGCGCGAGCCGGTCAAATTCCGCGAGCAGGTCGAAGAGCTGTTCCAGATGATGA
AGGACGGCAAGATCGATCCACTGGTGTCGGAGACCTTCCCGCTCGAGAAAGGCGGCGACGCGATCGCCAAGCTCGAAAAT
CGCCAGGCGGTGGGCAAGCTCGTCGTGCTGATGGATTGA

Upstream 100 bases:

>100_bases
AAGTCGGCCTGACCCTCACCCGCGATGCCGCCATCGCAGACTATGAATCGCGCCAAAAGACACAAACGCCCTGGCTTACA
ACAGGAACGGAGAGAGCCGC

Downstream 100 bases:

>100_bases
GGCCGGTTGCGGGTCGCCGCGCGCACGCCTATCTCGGAATGGCAACATCAGTCGAGGGACTCACATGACCGATTTCAAGG
ATCGCGAGCGCGCCGAAGAG

Product: alcohol dehydrogenase, zinc-containing

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKVLRTHAVGGPETLTLDEVEVPTPGKGEVLVDVKACAINYPDTLMIRDLYQFKPERPYAPGGEIAGVVEAVGEGVDGVS
VGDRVMAGIGNGGLTEKVIVPAGRMFPVPEGVPFEKAASLLMTYGTTIHGLKDRGHIKKGDTVLVLGAAGGVGLSAVELA
KAFGARVVAAVSSEEKGEVARKAGADEVVIYPKDEMDKAASKELASAFKAACGPEGANIVYDIVGGQYSEPALRSIAWEG
RFLVVGFPAGIAKMPLNLTLLKSCDIAGVFWGAFTAREPVKFREQVEELFQMMKDGKIDPLVSETFPLEKGGDAIAKLEN
RQAVGKLVVLMD

Sequences:

>Translated_332_residues
MKVLRTHAVGGPETLTLDEVEVPTPGKGEVLVDVKACAINYPDTLMIRDLYQFKPERPYAPGGEIAGVVEAVGEGVDGVS
VGDRVMAGIGNGGLTEKVIVPAGRMFPVPEGVPFEKAASLLMTYGTTIHGLKDRGHIKKGDTVLVLGAAGGVGLSAVELA
KAFGARVVAAVSSEEKGEVARKAGADEVVIYPKDEMDKAASKELASAFKAACGPEGANIVYDIVGGQYSEPALRSIAWEG
RFLVVGFPAGIAKMPLNLTLLKSCDIAGVFWGAFTAREPVKFREQVEELFQMMKDGKIDPLVSETFPLEKGGDAIAKLEN
RQAVGKLVVLMD
>Mature_332_residues
MKVLRTHAVGGPETLTLDEVEVPTPGKGEVLVDVKACAINYPDTLMIRDLYQFKPERPYAPGGEIAGVVEAVGEGVDGVS
VGDRVMAGIGNGGLTEKVIVPAGRMFPVPEGVPFEKAASLLMTYGTTIHGLKDRGHIKKGDTVLVLGAAGGVGLSAVELA
KAFGARVVAAVSSEEKGEVARKAGADEVVIYPKDEMDKAASKELASAFKAACGPEGANIVYDIVGGQYSEPALRSIAWEG
RFLVVGFPAGIAKMPLNLTLLKSCDIAGVFWGAFTAREPVKFREQVEELFQMMKDGKIDPLVSETFPLEKGGDAIAKLEN
RQAVGKLVVLMD

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=335, Percent_Identity=30.7462686567164, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI13236495, Length=335, Percent_Identity=30.7462686567164, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI22538446, Length=333, Percent_Identity=29.1291291291291, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI22538444, Length=333, Percent_Identity=29.1291291291291, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI194239676, Length=334, Percent_Identity=28.4431137724551, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI18379349, Length=323, Percent_Identity=30.030959752322, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI24308257, Length=355, Percent_Identity=25.6338028169014, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI28557745, Length=298, Percent_Identity=28.5234899328859, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI67078404, Length=310, Percent_Identity=26.7741935483871, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI67078406, Length=291, Percent_Identity=27.1477663230241, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI47519420, Length=341, Percent_Identity=28.4457478005865, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41872631, Length=254, Percent_Identity=27.5590551181102, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI197927207, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=331, Percent_Identity=31.4199395770393, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787863, Length=358, Percent_Identity=26.536312849162, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789651, Length=191, Percent_Identity=32.4607329842932, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082125, Length=377, Percent_Identity=25.7294429708223, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=333, Percent_Identity=30.03003003003, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536829, Length=300, Percent_Identity=30, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17556000, Length=217, Percent_Identity=30.8755760368664, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=261, Percent_Identity=26.8199233716475, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=337, Percent_Identity=29.9703264094956, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319258, Length=300, Percent_Identity=27, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=345, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550423, Length=325, Percent_Identity=26.7692307692308, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19920632, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330659, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581345, Length=254, Percent_Identity=23.6220472440945, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34998; Mature: 34998

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLRTHAVGGPETLTLDEVEVPTPGKGEVLVDVKACAINYPDTLMIRDLYQFKPERPYA
CCCEEECCCCCCCEEEECCEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCC
PGGEIAGVVEAVGEGVDGVSVGDRVMAGIGNGGLTEKVIVPAGRMFPVPEGVPFEKAASL
CCCHHHHHHHHHCCCCCCCCCCCHHHEECCCCCCCCEEEECCCCEECCCCCCCHHHHHHH
LMTYGTTIHGLKDRGHIKKGDTVLVLGAAGGVGLSAVELAKAFGARVVAAVSSEEKGEVA
HHHHCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHH
RKAGADEVVIYPKDEMDKAASKELASAFKAACGPEGANIVYDIVGGQYSEPALRSIAWEG
HHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCC
RFLVVGFPAGIAKMPLNLTLLKSCDIAGVFWGAFTAREPVKFREQVEELFQMMKDGKIDP
EEEEEEECCCHHHCCCCEEEECCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
LVSETFPLEKGGDAIAKLENRQAVGKLVVLMD
CHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MKVLRTHAVGGPETLTLDEVEVPTPGKGEVLVDVKACAINYPDTLMIRDLYQFKPERPYA
CCCEEECCCCCCCEEEECCEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCC
PGGEIAGVVEAVGEGVDGVSVGDRVMAGIGNGGLTEKVIVPAGRMFPVPEGVPFEKAASL
CCCHHHHHHHHHCCCCCCCCCCCHHHEECCCCCCCCEEEECCCCEECCCCCCCHHHHHHH
LMTYGTTIHGLKDRGHIKKGDTVLVLGAAGGVGLSAVELAKAFGARVVAAVSSEEKGEVA
HHHHCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHH
RKAGADEVVIYPKDEMDKAASKELASAFKAACGPEGANIVYDIVGGQYSEPALRSIAWEG
HHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCC
RFLVVGFPAGIAKMPLNLTLLKSCDIAGVFWGAFTAREPVKFREQVEELFQMMKDGKIDP
EEEEEEECCCHHHCCCCEEEECCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
LVSETFPLEKGGDAIAKLENRQAVGKLVVLMD
CHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]