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The map label for this gene is acpS

Identifier: 85373369

GI number: 85373369

Start: 579368

End: 579769

Strand: Reverse

Name: acpS

Synonym: ELI_02710

Alternate gene names: 85373369

Gene position: 579769-579368 (Counterclockwise)

Preceding gene: 85373370

Following gene: 85373368

Centisome position: 18.99

GC content: 62.94

Gene sequence:

>402_bases
GTGATCATCGGCTTGGGCTCAGACCTCTGCAATATCGAGCGGATCCAAAACTCGCTGGACCGCTTTGGCGAACGGTTCGA
GAACCGCGTCTTTACCGAGATCGAGCGTGCCAAGGCGCGGCGGCGGCCGTTCACGATTGCGGGCACCTATGCCAAGCGCT
TCGCCGCCAAGGAGGCCTTCAGCAAGGCGGTCGGCACCGGCTTCAGGCGCGGTGTTTTCATGAAGGATATCGGCGTGGTC
AACGCGCGATCCGGCGCGCCGACGCTTGCGCTGACCGGCGGGGCCGCTATTCGGCTTGCGGAATTGCTACCGGATGGCCA
TGAGGCATCCATTCATCTCACCCTCACCGACGATCACCCATGGGCGCAGGCCTTCGTGATCATCGAGGCCCACCGGATAT
GA

Upstream 100 bases:

>100_bases
CGCCCCGGCCTCCGAGCCGGGGTCCCGCTCCCTTGGGACCTGCGCTTGAAGAAAGCGGGACCCCGGATCAGGTCCGGGGC
GACGGCTTGAAGGAACCTTC

Downstream 100 bases:

>100_bases
CGACGAGTACCCCCACCCAAGTGACCGATACCGACATCAAAAAGAGCGAAGAAAAGGTCAACTGGTTCGCCGAATTGCGC
GGGCTCGGGCTGATGCTCTT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MIIGLGSDLCNIERIQNSLDRFGERFENRVFTEIERAKARRRPFTIAGTYAKRFAAKEAFSKAVGTGFRRGVFMKDIGVV
NARSGAPTLALTGGAAIRLAELLPDGHEASIHLTLTDDHPWAQAFVIIEAHRI

Sequences:

>Translated_133_residues
MIIGLGSDLCNIERIQNSLDRFGERFENRVFTEIERAKARRRPFTIAGTYAKRFAAKEAFSKAVGTGFRRGVFMKDIGVV
NARSGAPTLALTGGAAIRLAELLPDGHEASIHLTLTDDHPWAQAFVIIEAHRI
>Mature_133_residues
MIIGLGSDLCNIERIQNSLDRFGERFENRVFTEIERAKARRRPFTIAGTYAKRFAAKEAFSKAVGTGFRRGVFMKDIGVV
NARSGAPTLALTGGAAIRLAELLPDGHEASIHLTLTDDHPWAQAFVIIEAHRI

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=131, Percent_Identity=41.9847328244275, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_ERYLH (Q2NCF7)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457431.1
- ProteinModelPortal:   Q2NCF7
- SMR:   Q2NCF7
- STRING:   Q2NCF7
- GeneID:   3871770
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_02710
- NMPDR:   fig|314225.3.peg.2541
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q2NCF7
- ProtClustDB:   PRK00070
- BioCyc:   ELIT314225:ELI_02710-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14680; Mature: 14680

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLGSDLCNIERIQNSLDRFGERFENRVFTEIERAKARRRPFTIAGTYAKRFAAKEAF
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
SKAVGTGFRRGVFMKDIGVVNARSGAPTLALTGGAAIRLAELLPDGHEASIHLTLTDDHP
HHHHCCHHHCCEEEHHCCEEECCCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEEECCCC
WAQAFVIIEAHRI
CCEEEEEEEECCC
>Mature Secondary Structure
MIIGLGSDLCNIERIQNSLDRFGERFENRVFTEIERAKARRRPFTIAGTYAKRFAAKEAF
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
SKAVGTGFRRGVFMKDIGVVNARSGAPTLALTGGAAIRLAELLPDGHEASIHLTLTDDHP
HHHHCCHHHCCEEEHHCCEEECCCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEEECCCC
WAQAFVIIEAHRI
CCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA