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The map label for this gene is oxyR [H]

Identifier: 85373283

GI number: 85373283

Start: 494911

End: 495810

Strand: Reverse

Name: oxyR [H]

Synonym: ELI_02280

Alternate gene names: 85373283

Gene position: 495810-494911 (Counterclockwise)

Preceding gene: 85373287

Following gene: 85373280

Centisome position: 16.24

GC content: 65.78

Gene sequence:

>900_bases
ATGCCCACGCTTCGCCAATTGGAATATCTGGTCGCACTCGACGAGCTTGCCCATTTCGGCCGAGCTGCGGCCCGCTGTCA
CGTAAGCCAGCCAACGCTGAGCCAGCAATTGAAACAATTGGAGGAGCGGCTCGGCGTCACATTGGTCGAACGCGGCACCC
CTCCGGCGATGACGCCAACCGGCCGCGAACTCGCGCGGCGCGCGCGGCAGGTGCTCACCGAAGTCGAGGAAATCCGCCGT
CTGGCGGAGCAGAGCCGTTGCGGGATGGCCGGCACGATCCGTTTCGGCGTGACGCCGACGCTGGGCCCGTACCTGATGCC
TTCAGCGATCCTGCACCTGCACCGCGATTTTCCCGATCTGAAGCTCTACATCCGCGAAGGCATTCCGGACCAGCAGCTGG
CGGAGCTGGCTCGCGGCGAGCTCGACATGATGCTGGCACCCCTGCCCGTCGCCGAGCCGGGCCTGCATATCGAGCCGCTG
TTTCGCGAACCTCTGCAACTGGTCGGCCCGCCCGATCACAAGCTGGCGACAATGAAGGTGCGCGAGCCCGAGGACCTTGC
AGGGGAAGCCGTTCTCAGCATCGATCCGGCGCACCACCTGCACCGGCAAACCGAAGCCATGTGCGGCGAACTCGGCGCTT
ATCTCTTGCGCGACTACCAGGGCACCAGTCTCGACAGCGTGCGGCAGATGGCCGGGTCAGGCCTTGGACTGGCTTTCCTG
CCCGAGCTTTACCTGCGGGCCGAGACCGGCGGCGAGGACATGGTCACGCGGCTCGATATCGAAGGTTGGTCGGCCACCCG
CTCGATCGCCGCCGTCTGGCGCGAGCGCACGGCGTTAAGCGAGACCTATGCCGAGATCGCACAGCTCATCGCGGATCATG
CGCGCAGGCTTCTGGCCTGA

Upstream 100 bases:

>100_bases
CTCCAAGAGGTGGACATCACCCCGACAACGGCGAAATGGCGGATTGGTGCCGATAAACCCGATTGAAAGAATACCCCTTA
TTCGATAGTCAGAAACTATC

Downstream 100 bases:

>100_bases
CCGACGCCTGTGTAGCGTAGCGCTCAAATATCCTGCTCGACGTCGTCGGCCGGGAGGCCGGGGTCTACCCCGGTCAATTC
GACCGAAATCTCCCACAAAC

Product: hydrogen peroxide-inducible genes activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPTLRQLEYLVALDELAHFGRAAARCHVSQPTLSQQLKQLEERLGVTLVERGTPPAMTPTGRELARRARQVLTEVEEIRR
LAEQSRCGMAGTIRFGVTPTLGPYLMPSAILHLHRDFPDLKLYIREGIPDQQLAELARGELDMMLAPLPVAEPGLHIEPL
FREPLQLVGPPDHKLATMKVREPEDLAGEAVLSIDPAHHLHRQTEAMCGELGAYLLRDYQGTSLDSVRQMAGSGLGLAFL
PELYLRAETGGEDMVTRLDIEGWSATRSIAAVWRERTALSETYAEIAQLIADHARRLLA

Sequences:

>Translated_299_residues
MPTLRQLEYLVALDELAHFGRAAARCHVSQPTLSQQLKQLEERLGVTLVERGTPPAMTPTGRELARRARQVLTEVEEIRR
LAEQSRCGMAGTIRFGVTPTLGPYLMPSAILHLHRDFPDLKLYIREGIPDQQLAELARGELDMMLAPLPVAEPGLHIEPL
FREPLQLVGPPDHKLATMKVREPEDLAGEAVLSIDPAHHLHRQTEAMCGELGAYLLRDYQGTSLDSVRQMAGSGLGLAFL
PELYLRAETGGEDMVTRLDIEGWSATRSIAAVWRERTALSETYAEIAQLIADHARRLLA
>Mature_298_residues
PTLRQLEYLVALDELAHFGRAAARCHVSQPTLSQQLKQLEERLGVTLVERGTPPAMTPTGRELARRARQVLTEVEEIRRL
AEQSRCGMAGTIRFGVTPTLGPYLMPSAILHLHRDFPDLKLYIREGIPDQQLAELARGELDMMLAPLPVAEPGLHIEPLF
REPLQLVGPPDHKLATMKVREPEDLAGEAVLSIDPAHHLHRQTEAMCGELGAYLLRDYQGTSLDSVRQMAGSGLGLAFLP
ELYLRAETGGEDMVTRLDIEGWSATRSIAAVWRERTALSETYAEIAQLIADHARRLLA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=40.3448275862069, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787879, Length=256, Percent_Identity=33.203125, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=32.034632034632, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788887, Length=259, Percent_Identity=28.957528957529, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=28.4, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790262, Length=196, Percent_Identity=31.6326530612245, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787530, Length=302, Percent_Identity=23.841059602649, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI145693105, Length=241, Percent_Identity=25.3112033195021, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788297, Length=274, Percent_Identity=27.7372262773723, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788748, Length=303, Percent_Identity=26.0726072607261, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081904, Length=175, Percent_Identity=32.5714285714286, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788296, Length=161, Percent_Identity=29.8136645962733, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787806, Length=275, Percent_Identity=23.2727272727273, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33212; Mature: 33081

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLRQLEYLVALDELAHFGRAAARCHVSQPTLSQQLKQLEERLGVTLVERGTPPAMTPT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCC
GRELARRARQVLTEVEEIRRLAEQSRCGMAGTIRFGVTPTLGPYLMPSAILHLHRDFPDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHH
KLYIREGIPDQQLAELARGELDMMLAPLPVAEPGLHIEPLFREPLQLVGPPDHKLATMKV
HHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEC
REPEDLAGEAVLSIDPAHHLHRQTEAMCGELGAYLLRDYQGTSLDSVRQMAGSGLGLAFL
CCCHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHH
PELYLRAETGGEDMVTRLDIEGWSATRSIAAVWRERTALSETYAEIAQLIADHARRLLA
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTLRQLEYLVALDELAHFGRAAARCHVSQPTLSQQLKQLEERLGVTLVERGTPPAMTPT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCC
GRELARRARQVLTEVEEIRRLAEQSRCGMAGTIRFGVTPTLGPYLMPSAILHLHRDFPDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHH
KLYIREGIPDQQLAELARGELDMMLAPLPVAEPGLHIEPLFREPLQLVGPPDHKLATMKV
HHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEC
REPEDLAGEAVLSIDPAHHLHRQTEAMCGELGAYLLRDYQGTSLDSVRQMAGSGLGLAFL
CCCHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHH
PELYLRAETGGEDMVTRLDIEGWSATRSIAAVWRERTALSETYAEIAQLIADHARRLLA
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA