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The map label for this gene is ompR

Identifier: 85060297

GI number: 85060297

Start: 3982777

End: 3983496

Strand: Reverse

Name: ompR

Synonym: SG2319

Alternate gene names: 85060297

Gene position: 3983496-3982777 (Counterclockwise)

Preceding gene: 85060298

Following gene: 85060296

Centisome position: 95.5

GC content: 57.92

Gene sequence:

>720_bases
ATGCAAGAGAATTACAAAATCCTAGTTGTGGATGACGATATGCGCCTGCGGGCGCTCCTTGAGCGTTATTTGACCGAGCA
GGGCTTTCAGGTACGCAGCGTCGCCAACGCCGAACAGATGGACCGTTTGCTGACGCGTGAATCCTTCCATCTGATGGTGC
TGGATTTGATGCTGCCGGGAGAGGATGGGCTGTCTATTTGCCGCCGGCTGCGCAGCCAAAGCAACCCGATGCCGATCATT
ATGGTCACCGCCAAGGGGGAGGAAGTGGACCGCATTGTTGGCCTGGAAATCGGTGCCGATGACTATATTCCCAAGCCCTT
CAACCCCCGTGAACTGCTGGCGCGTATCCGCGCGGTACTACGCCGGCAGGCTAACGAGCTGCCGGGGGCGCCGTCGCAGG
AAGAGGCTATCATCGCCTTTGGCAAGTTCAAGCTTAATCTCGGTACCCGTGAGATGTTCCGCGAAGATGAGCCGATGCCG
CTGACCAGCGGTGAGTTCGCGGTGCTTAAAGCGTTGGTCAGCCACCCGCGGGAGCCGTTGTCCCGTGATAAACTGATGAA
TCTGGCGCGCGGCCGTGAATATAGCGCCATGGAACGCTCAATCGATGTGCAGATCTCGCGTCTGCGGCGCATGGTGGAAG
AAGATCCCGCCCATCCGCGCTATATTCAGACCGTATGGGGTCTGGGCTATGTCTTTGTGCCGGATGGCAGTAAAGCATGA

Upstream 100 bases:

>100_bases
TAACAATTTCGCTTAGAATGGTCACCTGAATTCGCTGTCAGTGATCCACCGGTTTTTGAACAATATCCTTTATGGGCGTT
TCGCCTTTGGGAGAGAGATA

Downstream 100 bases:

>100_bases
TGCGATGGCGCATCTCTCCGCGCAGTTCCTTCGCCCGCAGCCTCTTGTTAATCGTTACCTTGCTGTTCGTCAGCCTGGTA
ACGACCTACCTGGTGGTCTT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPII
MVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAIIAFGKFKLNLGTREMFREDEPMP
LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA

Sequences:

>Translated_239_residues
MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPII
MVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAIIAFGKFKLNLGTREMFREDEPMP
LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA
>Mature_239_residues
MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPII
MVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAIIAFGKFKLNLGTREMFREDEPMP
LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=99.581589958159, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=37.8723404255319, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.117903930131, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=36.0515021459227, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=40.6779661016949, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=34.4827586206897, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.6521739130435, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=33.4745762711864, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.2105263157895, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=33.4821428571429, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=32.7510917030568, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.0813008130081, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27368; Mature: 27368

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCHHEEEEEEECCC
EDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVL
CHHHHHHHHHHHCCCCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRQANELPGAPSQEEAIIAFGKFKLNLGTREMFREDEPMPLTSGEFAVLKALVSHPREPL
HHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCC
SRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCHHEEEEEEECCC
EDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVL
CHHHHHHHHHHHCCCCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRQANELPGAPSQEEAIIAFGKFKLNLGTREMFREDEPMPLTSGEFAVLKALVSHPREPL
HHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCC
SRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]