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The map label for this gene is rpe [H]

Identifier: 85060283

GI number: 85060283

Start: 3964206

End: 3964886

Strand: Reverse

Name: rpe [H]

Synonym: SG2305

Alternate gene names: 85060283

Gene position: 3964886-3964206 (Counterclockwise)

Preceding gene: 85060284

Following gene: 85060282

Centisome position: 95.06

GC content: 57.27

Gene sequence:

>681_bases
ATGAAAAACTATTTAATCGCTCCTTCCATCCTTTCCGCGGATTTTGCCCGCCTGGGTGGAGATACTGCCCGGGTGTTAGC
CGCCGGGGCGGACGTGGTGCATTTTGATGTGATGGATAATCATTATGTTCCGAATCTCACCATGGGGCCGATGGTGCTTA
AAGCGCTGCGTAACTATGGCATTACCGCCCCCATTGACGTGCATTTGATGGTAAAGCCGGTCGATCGCCTGATCCCGGAT
TTTGCCGCCGCCGGCGCCAGTTACATTACCTTCCACCCGGAGGCGTCGCAGCATGTTGACCGCTCACTGCAGCTCATCAA
GGAGCACGGCTGCAAAGCCGGGCTGGTCTTCAATCCCGCCACGCCGCTAAGCTGCCTTGAGTATGTGATGGATAAACTTG
ATGTCATTTTGCTGATGTCGGTCAACCCCGGTTTTGGAGGCCAGTCTTTCCTGCCTTCGACCCTGGATAAATTGCGCCAG
GCGCGTCAGATTATCGATCGCAGCGGCAGGGATATCCGGCTTGAGGTGGACGGCGGCGTCAAAGTGGACAACATCGGCGC
TATCGCCGCCGCGGGCGCCGATATGTTCGTTGCCGGCTCTGCTATATTCAGCCAGCCGGATTACCGACCCGTTATCGACG
CCATGCGTCAGGCATTAGCGGGAGCGGCGGGGAATGCGTGA

Upstream 100 bases:

>100_bases
GCAATATTTTCGGGCGCAGCAGCGTGAATGAACTGCTGGCGTTATATCTCTGAGCGGGGCCGCCCCGCCGCAGACTGACC
GTAACTGACGGGAGACATGG

Downstream 100 bases:

>100_bases
AGAACAGCCTATCCGCGGTATCGCATTCGATCTTGACGGCACTTTGACCGACAGCGCCCCCGGCTTAACGGTCGCTCTTG
ATCGAACGCTGTCAGAGCAG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKNYLIAPSILSADFARLGGDTARVLAAGADVVHFDVMDNHYVPNLTMGPMVLKALRNYGITAPIDVHLMVKPVDRLIPD
FAAAGASYITFHPEASQHVDRSLQLIKEHGCKAGLVFNPATPLSCLEYVMDKLDVILLMSVNPGFGGQSFLPSTLDKLRQ
ARQIIDRSGRDIRLEVDGGVKVDNIGAIAAAGADMFVAGSAIFSQPDYRPVIDAMRQALAGAAGNA

Sequences:

>Translated_226_residues
MKNYLIAPSILSADFARLGGDTARVLAAGADVVHFDVMDNHYVPNLTMGPMVLKALRNYGITAPIDVHLMVKPVDRLIPD
FAAAGASYITFHPEASQHVDRSLQLIKEHGCKAGLVFNPATPLSCLEYVMDKLDVILLMSVNPGFGGQSFLPSTLDKLRQ
ARQIIDRSGRDIRLEVDGGVKVDNIGAIAAAGADMFVAGSAIFSQPDYRPVIDAMRQALAGAAGNA
>Mature_226_residues
MKNYLIAPSILSADFARLGGDTARVLAAGADVVHFDVMDNHYVPNLTMGPMVLKALRNYGITAPIDVHLMVKPVDRLIPD
FAAAGASYITFHPEASQHVDRSLQLIKEHGCKAGLVFNPATPLSCLEYVMDKLDVILLMSVNPGFGGQSFLPSTLDKLRQ
ARQIIDRSGRDIRLEVDGGVKVDNIGAIAAAGADMFVAGSAIFSQPDYRPVIDAMRQALAGAAGNA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=219, Percent_Identity=40.1826484018265, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI219879828, Length=219, Percent_Identity=38.3561643835616, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI24307923, Length=175, Percent_Identity=33.1428571428571, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1789788, Length=220, Percent_Identity=86.3636363636364, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=37.5634517766497, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790754, Length=208, Percent_Identity=29.3269230769231, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=222, Percent_Identity=39.1891891891892, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322341, Length=232, Percent_Identity=37.5, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=40.7582938388626, Blast_Score=157, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24145; Mature: 24145

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYLIAPSILSADFARLGGDTARVLAAGADVVHFDVMDNHYVPNLTMGPMVLKALRNYG
CCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ITAPIDVHLMVKPVDRLIPDFAAAGASYITFHPEASQHVDRSLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLSCLEYVMDKLDVILLMSVNPGFGGQSFLPSTLDKLRQARQIIDRSGRDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCE
KVDNIGAIAAAGADMFVAGSAIFSQPDYRPVIDAMRQALAGAAGNA
EECCCCHHHHCCCCCEEECHHHHCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNYLIAPSILSADFARLGGDTARVLAAGADVVHFDVMDNHYVPNLTMGPMVLKALRNYG
CCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ITAPIDVHLMVKPVDRLIPDFAAAGASYITFHPEASQHVDRSLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLSCLEYVMDKLDVILLMSVNPGFGGQSFLPSTLDKLRQARQIIDRSGRDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCE
KVDNIGAIAAAGADMFVAGSAIFSQPDYRPVIDAMRQALAGAAGNA
EECCCCHHHHCCCCCEEECHHHHCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]