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The map label for this gene is argB

Identifier: 85060138

GI number: 85060138

Start: 3762204

End: 3762977

Strand: Reverse

Name: argB

Synonym: SG2160

Alternate gene names: 85060138

Gene position: 3762977-3762204 (Counterclockwise)

Preceding gene: 85060140

Following gene: 85060137

Centisome position: 90.21

GC content: 60.85

Gene sequence:

>774_bases
ATGAATCCATTGATTATCAAACTGGGCGGCGTTTTGCTGGATAGCGACGAGGCGCTGGAGCGTTTGTTTACCGCGCTGGA
CAGTTATCGCGCCGAGCACCGGTGCCCTTTGCTTATCGTCCACGGCGGCGGTTGCCTGGTGGACGAGTTGATGCACAAAC
TTTCCCTGCCGGTGGTAAAGAAAAACGGCCTGCGGGTGACGCCTGCGGATCAGATCGCGATTATTACCGGCGCGCTGGCC
GGCACCGCCAATAAAACGTTGCTGGCGTGGGCGAAAAAACACGCCATCAATGCGGTAGGACTGTGCCTCGGGGATGGCGA
TAGCGTGAACGTCACGCCGCTCGATCCGGCGCTGGGTCATGTCGGCCGTGCTCACCCCGGTTCGCCGGTGCTGCTGACGA
CGCTGTTGGAGGCGGGCTATCTGCCCATTATTAGCTCGATTGGGCTGACCCATGACGGCGAACTGATGAACGTTAACGCC
GATCAGGCGGCCACCGCGCTGGCCGCTACGTTGGGCGCCGACCTGATTTTGCTATCGGACATCAGCGGGATTCTCGATGG
CAAAGGCCAACGCATCGCGGAAATGACCGCCCAGAAAGCCGAGCAATTAATCGAGCAGGGGATCATCACCGACGGTATGA
TAGTGAAGGTCAACGCCGCGCTTGATGCGGCCCGAACGCTGGGCAGGCCGGTGGATATCGCCAGCTGGCGGCACGCCGAG
CAACTGCCGGCGCTGTTCAACGGCGTTGCCATCGGCACCCGTATACTGGCCTGA

Upstream 100 bases:

>100_bases
TAAAAGGGGCGGCGGCGAAGGCGGTGCAGTGCGCCAATATCCGTTTTGATTTTGCGCAGACGCTGGCGCTTTGCTAAGCA
CTAATGAGGCCAATAACATA

Downstream 100 bases:

>100_bases
TTGCCGGCCTCGCCGGCAGCGTGACGCCGGCCGGTTCGTTTTACCCTCTTACGGCGCGGCACGAGGCCGCGTACGCACCT
TTACCGCGCGCGGTGCGCGT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNPLIIKLGGVLLDSDEALERLFTALDSYRAEHRCPLLIVHGGGCLVDELMHKLSLPVVKKNGLRVTPADQIAIITGALA
GTANKTLLAWAKKHAINAVGLCLGDGDSVNVTPLDPALGHVGRAHPGSPVLLTTLLEAGYLPIISSIGLTHDGELMNVNA
DQAATALAATLGADLILLSDISGILDGKGQRIAEMTAQKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAE
QLPALFNGVAIGTRILA

Sequences:

>Translated_257_residues
MNPLIIKLGGVLLDSDEALERLFTALDSYRAEHRCPLLIVHGGGCLVDELMHKLSLPVVKKNGLRVTPADQIAIITGALA
GTANKTLLAWAKKHAINAVGLCLGDGDSVNVTPLDPALGHVGRAHPGSPVLLTTLLEAGYLPIISSIGLTHDGELMNVNA
DQAATALAATLGADLILLSDISGILDGKGQRIAEMTAQKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAE
QLPALFNGVAIGTRILA
>Mature_257_residues
MNPLIIKLGGVLLDSDEALERLFTALDSYRAEHRCPLLIVHGGGCLVDELMHKLSLPVVKKNGLRVTPADQIAIITGALA
GTANKTLLAWAKKHAINAVGLCLGDGDSVNVTPLDPALGHVGRAHPGSPVLLTTLLEAGYLPIISSIGLTHDGELMNVNA
DQAATALAATLGADLILLSDISGILDGKGQRIAEMTAQKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAE
QLPALFNGVAIGTRILA

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=257, Percent_Identity=84.4357976653696, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SODGM (Q2NQZ0)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455840.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q2NQZ0
- SMR:   Q2NQZ0
- STRING:   Q2NQZ0
- GeneID:   3868269
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2160
- NMPDR:   fig|343509.6.peg.4761
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- PhylomeDB:   Q2NQZ0
- ProtClustDB:   PRK00942
- BioCyc:   SGLO343509:SG2160-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26819; Mature: 26819

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: BINDING 65-65 BINDING 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLIIKLGGVLLDSDEALERLFTALDSYRAEHRCPLLIVHGGGCLVDELMHKLSLPVVK
CCCEEEEECCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEE
KNGLRVTPADQIAIITGALAGTANKTLLAWAKKHAINAVGLCLGDGDSVNVTPLDPALGH
CCCEEECCCCCEEEEEEHHCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEECCHHHHC
VGRAHPGSPVLLTTLLEAGYLPIISSIGLTHDGELMNVNADQAATALAATLGADLILLSD
CCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHCCCEEEEHH
ISGILDGKGQRIAEMTAQKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAE
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCCCCCHHCCCCHH
QLPALFNGVAIGTRILA
HHHHHHHHHHHHHEECC
>Mature Secondary Structure
MNPLIIKLGGVLLDSDEALERLFTALDSYRAEHRCPLLIVHGGGCLVDELMHKLSLPVVK
CCCEEEEECCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEE
KNGLRVTPADQIAIITGALAGTANKTLLAWAKKHAINAVGLCLGDGDSVNVTPLDPALGH
CCCEEECCCCCEEEEEEHHCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEECCHHHHC
VGRAHPGSPVLLTTLLEAGYLPIISSIGLTHDGELMNVNADQAATALAATLGADLILLSD
CCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHCCCEEEEHH
ISGILDGKGQRIAEMTAQKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAE
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCCCCCHHCCCCHH
QLPALFNGVAIGTRILA
HHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA