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The map label for this gene is invG [H]

Identifier: 85060069

GI number: 85060069

Start: 3596667

End: 3598307

Strand: Reverse

Name: invG [H]

Synonym: SG2091

Alternate gene names: 85060069

Gene position: 3598307-3596667 (Counterclockwise)

Preceding gene: 85060070

Following gene: 85060068

Centisome position: 86.27

GC content: 59.66

Gene sequence:

>1641_bases
ATGAATAACATCGCTCTGATAGGCCGCGGCTTGCTCTGCGTTATGTTACTGGCCTGCACCGGCCTTCTTGCAGGCGCGCG
GGCGGCGGAGTTACCCCGACAAGGCGACGGCTATGTGGCAAACAAAGACGGCGTTAAAGTGTTTTTCGACGCGCTTTCGG
CGCGCCTCAACCAGCCGGTCATTGTCAGCAAGCTGGCGGCGCGTAAGCAAATTAGCGGCGAATTCGATTTGGCTGATCCG
CGAGCGCTGCTGGCGCGCATTACCCAGCAGATGGGGATGATGTGGTACAGCGACGGCCAGGCTATTTATATCTATGACGC
CAGTGAAACGCGTCACGCGGTGGTGGCGCTGCGTACGATCTTGCCGGCGGCGCTGCGTCATTTTTTGCAGCAGGCCCAGC
TGCATGACCCGCGCTATCCGCTGCGGGGGGATCCCGGCGGACGACTCCTTTATCTTTCAGGCCCGCCGATGTATGTCGAA
CTGGTGGAAAACGCAGCCCGCCTGCTGGATAAGGAACCGGATGGAATACACGATCGCGAGCAGGCCGAGGTTATCCCGCT
AAGCTACACCTTTGTCGGCGATCGTTATTATGCCTTGCGCGGCGAAAAGGTGACCATTCCCGGTATCGCCACGGTGATAG
AGCGGCTGATGAGGCGGGAAGGGCGATCGGCGGTGGCTGACGTTCCTGCCCCGCTGACGCCGGCTGAGGCCCTGTTGCCT
GTAGCGGAGGTGCGCGCGGAACAGGATGTGGAACCGCTGCCGCTGTGGCCTGTACAGGTGATTGCCAATCCCAGCAATAA
CAGCCTGCTGGTCAAGGGTACCGGCCGCCAGGTCCAATTCGTGCGCAATCTGGTGCGTTCACTGGATATACCGAAGCGCC
ACGTGGAGTTATCGTTATGGATAATTGATTTGGAAAAGAGCGATCTTGATCAATTCGGCATCAATTGGCAGGGCGGCGCC
CGCATTGGCCAGCGCGGGGGCGTCACGCTCAATCAGGGATCCTATAGCGCGCTGGACGGTACGCGGTTTGTCGCCTCCAT
ATTGGCGCTGGCGCGGAAACACCGCGCCAACATTGTCTCGCGGCCGATTATCCTGACCCAGGAAAATGTGCCGGCGATTT
TCGATAACAACAGGACCTTTTATACTCGGCTTCTGGGAGAACGCAGCGTGGAGCTGCGCGAAGTGACCTACGGTACCATG
ATAAGCGTCCTGCCGCGGTTTTCCGGCGACGATCAAATTGAGATGGTGTTGACCATCGAAGACGGCGGCGAGGTCTCCCG
GCGGCAGAGTAATCCCGGCTCTGACGACCTGCCGGAAGTGGGCCGGACCCATATCAGTACGGTCGCGCGCGTGCCGCGGG
GAAAAAGCCTGCTGATTGGCGGCTACACCCGCGATGAGCTCAGGGGTAACCGCGCCCGGTTACCCGGTCTCGGGTCGATA
CCGCTGATTGGCGGGCTGTTTCGCCACCGCATCGATAAACAGGCCAATATGGTCAGGGTTTTTCTCATCCAGCCGCGGGA
AATTTCTGAGCCGCTGCAGCAAGACGCCGCCGCGTTTGCCCGTTCAATTACTGCTACTGCGCGCAGCCATGAAGGCACAC
TGAAGGACTGGGCCGATAATTATCTTGCCAGCCAGCACTGA

Upstream 100 bases:

>100_bases
ATGGCTATGCCTCGTCCTCGCACCTCTCCAACGATGTCAGGGACGCCTTTGGGGTTTCCCCCCGCGGGATATGGAATATG
ATCAACAAGAAAGCGGAACA

Downstream 100 bases:

>100_bases
CCGGCAAAATAATGCTCTGATTGCTGGATCACGCTACGATGAAAATTCTTATTAGCTGAGAATATGGGCGCTGGTTTACC
CGGCGGTGAGTAAATGTGGT

Product: type III secretion apparatus InvG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MNNIALIGRGLLCVMLLACTGLLAGARAAELPRQGDGYVANKDGVKVFFDALSARLNQPVIVSKLAARKQISGEFDLADP
RALLARITQQMGMMWYSDGQAIYIYDASETRHAVVALRTILPAALRHFLQQAQLHDPRYPLRGDPGGRLLYLSGPPMYVE
LVENAARLLDKEPDGIHDREQAEVIPLSYTFVGDRYYALRGEKVTIPGIATVIERLMRREGRSAVADVPAPLTPAEALLP
VAEVRAEQDVEPLPLWPVQVIANPSNNSLLVKGTGRQVQFVRNLVRSLDIPKRHVELSLWIIDLEKSDLDQFGINWQGGA
RIGQRGGVTLNQGSYSALDGTRFVASILALARKHRANIVSRPIILTQENVPAIFDNNRTFYTRLLGERSVELREVTYGTM
ISVLPRFSGDDQIEMVLTIEDGGEVSRRQSNPGSDDLPEVGRTHISTVARVPRGKSLLIGGYTRDELRGNRARLPGLGSI
PLIGGLFRHRIDKQANMVRVFLIQPREISEPLQQDAAAFARSITATARSHEGTLKDWADNYLASQH

Sequences:

>Translated_546_residues
MNNIALIGRGLLCVMLLACTGLLAGARAAELPRQGDGYVANKDGVKVFFDALSARLNQPVIVSKLAARKQISGEFDLADP
RALLARITQQMGMMWYSDGQAIYIYDASETRHAVVALRTILPAALRHFLQQAQLHDPRYPLRGDPGGRLLYLSGPPMYVE
LVENAARLLDKEPDGIHDREQAEVIPLSYTFVGDRYYALRGEKVTIPGIATVIERLMRREGRSAVADVPAPLTPAEALLP
VAEVRAEQDVEPLPLWPVQVIANPSNNSLLVKGTGRQVQFVRNLVRSLDIPKRHVELSLWIIDLEKSDLDQFGINWQGGA
RIGQRGGVTLNQGSYSALDGTRFVASILALARKHRANIVSRPIILTQENVPAIFDNNRTFYTRLLGERSVELREVTYGTM
ISVLPRFSGDDQIEMVLTIEDGGEVSRRQSNPGSDDLPEVGRTHISTVARVPRGKSLLIGGYTRDELRGNRARLPGLGSI
PLIGGLFRHRIDKQANMVRVFLIQPREISEPLQQDAAAFARSITATARSHEGTLKDWADNYLASQH
>Mature_546_residues
MNNIALIGRGLLCVMLLACTGLLAGARAAELPRQGDGYVANKDGVKVFFDALSARLNQPVIVSKLAARKQISGEFDLADP
RALLARITQQMGMMWYSDGQAIYIYDASETRHAVVALRTILPAALRHFLQQAQLHDPRYPLRGDPGGRLLYLSGPPMYVE
LVENAARLLDKEPDGIHDREQAEVIPLSYTFVGDRYYALRGEKVTIPGIATVIERLMRREGRSAVADVPAPLTPAEALLP
VAEVRAEQDVEPLPLWPVQVIANPSNNSLLVKGTGRQVQFVRNLVRSLDIPKRHVELSLWIIDLEKSDLDQFGINWQGGA
RIGQRGGVTLNQGSYSALDGTRFVASILALARKHRANIVSRPIILTQENVPAIFDNNRTFYTRLLGERSVELREVTYGTM
ISVLPRFSGDDQIEMVLTIEDGGEVSRRQSNPGSDDLPEVGRTHISTVARVPRGKSLLIGGYTRDELRGNRARLPGLGSI
PLIGGLFRHRIDKQANMVRVFLIQPREISEPLQQDAAAFARSITATARSHEGTLKDWADNYLASQH

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=266, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 60327; Mature: 60327

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIALIGRGLLCVMLLACTGLLAGARAAELPRQGDGYVANKDGVKVFFDALSARLNQPV
CCCEEEEHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEECCCCHHHHHHHHHHHCCCCH
IVSKLAARKQISGEFDLADPRALLARITQQMGMMWYSDGQAIYIYDASETRHAVVALRTI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHH
LPAALRHFLQQAQLHDPRYPLRGDPGGRLLYLSGPPMYVELVENAARLLDKEPDGIHDRE
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCC
QAEVIPLSYTFVGDRYYALRGEKVTIPGIATVIERLMRREGRSAVADVPAPLTPAEALLP
CCEEEEEEEEEECCEEEEEECCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VAEVRAEQDVEPLPLWPVQVIANPSNNSLLVKGTGRQVQFVRNLVRSLDIPKRHVELSLW
HHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEE
IIDLEKSDLDQFGINWQGGARIGQRGGVTLNQGSYSALDGTRFVASILALARKHRANIVS
EEECCCCCHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RPIILTQENVPAIFDNNRTFYTRLLGERSVELREVTYGTMISVLPRFSGDDQIEMVLTIE
CCEEEECCCCCEEEECCCEEEEEHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
DGGEVSRRQSNPGSDDLPEVGRTHISTVARVPRGKSLLIGGYTRDELRGNRARLPGLGSI
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCCCCCC
PLIGGLFRHRIDKQANMVRVFLIQPREISEPLQQDAAAFARSITATARSHEGTLKDWADN
HHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YLASQH
HHCCCC
>Mature Secondary Structure
MNNIALIGRGLLCVMLLACTGLLAGARAAELPRQGDGYVANKDGVKVFFDALSARLNQPV
CCCEEEEHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEECCCCHHHHHHHHHHHCCCCH
IVSKLAARKQISGEFDLADPRALLARITQQMGMMWYSDGQAIYIYDASETRHAVVALRTI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHH
LPAALRHFLQQAQLHDPRYPLRGDPGGRLLYLSGPPMYVELVENAARLLDKEPDGIHDRE
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCC
QAEVIPLSYTFVGDRYYALRGEKVTIPGIATVIERLMRREGRSAVADVPAPLTPAEALLP
CCEEEEEEEEEECCEEEEEECCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VAEVRAEQDVEPLPLWPVQVIANPSNNSLLVKGTGRQVQFVRNLVRSLDIPKRHVELSLW
HHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEE
IIDLEKSDLDQFGINWQGGARIGQRGGVTLNQGSYSALDGTRFVASILALARKHRANIVS
EEECCCCCHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RPIILTQENVPAIFDNNRTFYTRLLGERSVELREVTYGTMISVLPRFSGDDQIEMVLTIE
CCEEEECCCCCEEEECCCEEEEEHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
DGGEVSRRQSNPGSDDLPEVGRTHISTVARVPRGKSLLIGGYTRDELRGNRARLPGLGSI
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCCCCCC
PLIGGLFRHRIDKQANMVRVFLIQPREISEPLQQDAAAFARSITATARSHEGTLKDWADN
HHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YLASQH
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868245; 7997169; 11677609 [H]