Click here to switch to the map view.

The map label for this gene is invA [H]

Identifier: 85060068

GI number: 85060068

Start: 3594288

End: 3596285

Strand: Reverse

Name: invA [H]

Synonym: SG2090

Alternate gene names: 85060068

Gene position: 3596285-3594288 (Counterclockwise)

Preceding gene: 85060069

Following gene: 85060067

Centisome position: 86.22

GC content: 55.81

Gene sequence:

>1998_bases
GTGCTTAATAGATTTTTAAACCACATTTATTATCGTCCAGAATTATTAATTCTTGTGCTGGTTATTACAATAATTTTTAT
GATAATAATTCCTCTTCCAGCTTATCTGGTGGATTTTCTTATTGGCCTGAATATCGTCATCGCCATGCTGGTCTTCATTG
GCGCGTTTTACATCGATCGCATCCTGAGCTTCTCCACTTTTCCTGCCGTGCTGCTCATAACAACCCTGTTCAGACTGGCG
CTGACGATAAGCACCAGCCGACTTATCCTGACCGACGCCGACGCGGGCGAGATCATTGCCACCTTCGGCCAGTTTGTGAT
TGGCGATAATCTCGTCGTCGGGTTTGTCATTTTTGCCATCGTGACCGTGGTGCAGTTTATCGTCATCACCAAAGGATCGG
AGCGCGTCGCCGAGGTGGCCGCGCGCTTTTGTCTGGACGGCATGCCCGGCAAGCAGATGAGCATTGACGCCGACTTGCGC
GGTGGTGTGATTGACGCCGAAGGGGCCCGGCAACGGCGCAGCGTACTGGAGCGTGAAAGCCAGCTCTACGGCGCCTTCGA
CGGTGCAATGAAATTTATCAAGGGCGACGCCATCGCCAGTATTATCGTCGCCTTCGTCAACTTTATCGGCGGTATCGCGG
TGGGAATGAACCAACATCACATGGATCTGTCCCAGGCGCTGTCCACCTTCACCCTGCTGACTATCGGCGACGGTCTGGTC
GGCCAGATCCCGGCTTTGCTGATCTCAATCAGCGCAGGCCTCATCGTCACCCGTGTCAACGGCGATGGCGACAATCTGGG
CCGTAATATCATGCAGCAATTGCTCGGGAATCCCTTCGTGCTGCTGGTCACCGCTGTACTGGCCTTATCCATCGGCATGC
TGCCGGGTTTCCCTCTGCCGGTGTTCGTCATGCTGGCCATGGCGCTCGGCACATTGCTGCTAATGCGCCAGCGGCAGACC
CGCGTCGTCCCGCTGCCGGCGGCGGCAGATTACGCCGGCGGCTATCCGGAACGGATAATGCCCGAGGCGCTGGCCGTGAT
CCTGCAGGTGTCGCGCGCCAATTACGCCCGGTTGGAAAAAGAGCAATTGTGCGAACGGCTGCGCGGGCAGTTCCTCATCG
ACTTTGGCGTCGCGTTGCCACCCCTGATGCTGTGTCCTTGTGAACACACGGACGATCGGACGGTGGTGGTGGTGCTCAAT
GAAATTCGCGCTGATGTGTTCACCCTCCATTTCGATATGCTGCGCCGCGTGATACCCGGCGATCGTCCCTGTCCGCCCGA
CGTGACATTACATCAGGAGCAGGAAGCGGTCTGGGCGGCGCTTGACGATCGTGAGAGGCTGCTTGCCACGGGGTGCGTGC
TACGGCCGGCGGTAGATGAACTTTATCACTGTTTCGCGGTGATGCTGACTCACCACGTCAACGAATTTTTCGGCGTGCAG
GAAACTAAGCACCTGCTGGACCAAATGGAAAGCCACGCGCCAGATTTGCTCAAGGAAGTGTTGCGCCACGCGACGGTACA
GCGCATTGCCGAACTGCTGCAGCGGCTGTTGATGGAGCGTATCTCCATCCGTCACTTGAAACTCATTATGGAGGCGATGG
CCCTGTGGGCGCCACGGGAAAAAGATGTGTCCGCCCTGGTGGAGCACGTACGCTGCGCGCTGGCGCGCTATATCTGTCAC
CAATTCGCCGCCGATAATCTGTTGAGGGTGATCATGTTGTCGTCTGAGGTGGAGGAGACGCTGCGTGACAGCCTTCACAC
CACTTCAGCGGGCACCTTTCTCAATCTCGGTCCTCAGGTGTCGGAAGAATTGATGGAGCTGTTTACCTCCGCCCTGGAAA
GCTTGCCCATCGCTCAGCGCGATATCGTCCTGTTGGCGGCGGCGGATATTCGACGTTTTATCAAGTCCCTTATTCAACAT
CGTTTTCGCGATCTTGAAGTGCTGTCATTCGGTGAATTAACGGAAAGCGTTACCGTAAATGTCATCAAAACAATTTAA

Upstream 100 bases:

>100_bases
GGGATTTTGAGCAAAGCGTTGCCGGCTGCGGGGAATATCGAATGGCGGTCATCGTGTCTTTATTTGATATCTATCTGGCT
GAACGAAATGGATTATTCAC

Downstream 100 bases:

>100_bases
ACCAAGAGGAAAACGACATGTACGTTGATATTGCGGCATTGGTGCGTGAGGCGCTGCTGGACAGCGGCTGTGATCCCAGT
TTACTGGGGAGTTTCGACAG

Product: type III secretion apparatus InvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MLNRFLNHIYYRPELLILVLVITIIFMIIIPLPAYLVDFLIGLNIVIAMLVFIGAFYIDRILSFSTFPAVLLITTLFRLA
LTISTSRLILTDADAGEIIATFGQFVIGDNLVVGFVIFAIVTVVQFIVITKGSERVAEVAARFCLDGMPGKQMSIDADLR
GGVIDAEGARQRRSVLERESQLYGAFDGAMKFIKGDAIASIIVAFVNFIGGIAVGMNQHHMDLSQALSTFTLLTIGDGLV
GQIPALLISISAGLIVTRVNGDGDNLGRNIMQQLLGNPFVLLVTAVLALSIGMLPGFPLPVFVMLAMALGTLLLMRQRQT
RVVPLPAAADYAGGYPERIMPEALAVILQVSRANYARLEKEQLCERLRGQFLIDFGVALPPLMLCPCEHTDDRTVVVVLN
EIRADVFTLHFDMLRRVIPGDRPCPPDVTLHQEQEAVWAALDDRERLLATGCVLRPAVDELYHCFAVMLTHHVNEFFGVQ
ETKHLLDQMESHAPDLLKEVLRHATVQRIAELLQRLLMERISIRHLKLIMEAMALWAPREKDVSALVEHVRCALARYICH
QFAADNLLRVIMLSSEVEETLRDSLHTTSAGTFLNLGPQVSEELMELFTSALESLPIAQRDIVLLAAADIRRFIKSLIQH
RFRDLEVLSFGELTESVTVNVIKTI

Sequences:

>Translated_665_residues
MLNRFLNHIYYRPELLILVLVITIIFMIIIPLPAYLVDFLIGLNIVIAMLVFIGAFYIDRILSFSTFPAVLLITTLFRLA
LTISTSRLILTDADAGEIIATFGQFVIGDNLVVGFVIFAIVTVVQFIVITKGSERVAEVAARFCLDGMPGKQMSIDADLR
GGVIDAEGARQRRSVLERESQLYGAFDGAMKFIKGDAIASIIVAFVNFIGGIAVGMNQHHMDLSQALSTFTLLTIGDGLV
GQIPALLISISAGLIVTRVNGDGDNLGRNIMQQLLGNPFVLLVTAVLALSIGMLPGFPLPVFVMLAMALGTLLLMRQRQT
RVVPLPAAADYAGGYPERIMPEALAVILQVSRANYARLEKEQLCERLRGQFLIDFGVALPPLMLCPCEHTDDRTVVVVLN
EIRADVFTLHFDMLRRVIPGDRPCPPDVTLHQEQEAVWAALDDRERLLATGCVLRPAVDELYHCFAVMLTHHVNEFFGVQ
ETKHLLDQMESHAPDLLKEVLRHATVQRIAELLQRLLMERISIRHLKLIMEAMALWAPREKDVSALVEHVRCALARYICH
QFAADNLLRVIMLSSEVEETLRDSLHTTSAGTFLNLGPQVSEELMELFTSALESLPIAQRDIVLLAAADIRRFIKSLIQH
RFRDLEVLSFGELTESVTVNVIKTI
>Mature_665_residues
MLNRFLNHIYYRPELLILVLVITIIFMIIIPLPAYLVDFLIGLNIVIAMLVFIGAFYIDRILSFSTFPAVLLITTLFRLA
LTISTSRLILTDADAGEIIATFGQFVIGDNLVVGFVIFAIVTVVQFIVITKGSERVAEVAARFCLDGMPGKQMSIDADLR
GGVIDAEGARQRRSVLERESQLYGAFDGAMKFIKGDAIASIIVAFVNFIGGIAVGMNQHHMDLSQALSTFTLLTIGDGLV
GQIPALLISISAGLIVTRVNGDGDNLGRNIMQQLLGNPFVLLVTAVLALSIGMLPGFPLPVFVMLAMALGTLLLMRQRQT
RVVPLPAAADYAGGYPERIMPEALAVILQVSRANYARLEKEQLCERLRGQFLIDFGVALPPLMLCPCEHTDDRTVVVVLN
EIRADVFTLHFDMLRRVIPGDRPCPPDVTLHQEQEAVWAALDDRERLLATGCVLRPAVDELYHCFAVMLTHHVNEFFGVQ
ETKHLLDQMESHAPDLLKEVLRHATVQRIAELLQRLLMERISIRHLKLIMEAMALWAPREKDVSALVEHVRCALARYICH
QFAADNLLRVIMLSSEVEETLRDSLHTTSAGTFLNLGPQVSEELMELFTSALESLPIAQRDIVLLAAADIRRFIKSLIQH
RFRDLEVLSFGELTESVTVNVIKTI

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the invE protein [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=678, Percent_Identity=33.0383480825959, Blast_Score=328, Evalue=8e-91,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 73844; Mature: 73844

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRFLNHIYYRPELLILVLVITIIFMIIIPLPAYLVDFLIGLNIVIAMLVFIGAFYIDR
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSFSTFPAVLLITTLFRLALTISTSRLILTDADAGEIIATFGQFVIGDNLVVGFVIFAI
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHH
VTVVQFIVITKGSERVAEVAARFCLDGMPGKQMSIDADLRGGVIDAEGARQRRSVLERES
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCHHHHHHHHHHHH
QLYGAFDGAMKFIKGDAIASIIVAFVNFIGGIAVGMNQHHMDLSQALSTFTLLTIGDGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHH
GQIPALLISISAGLIVTRVNGDGDNLGRNIMQQLLGNPFVLLVTAVLALSIGMLPGFPLP
HHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
VFVMLAMALGTLLLMRQRQTRVVPLPAAADYAGGYPERIMPEALAVILQVSRANYARLEK
HHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
EQLCERLRGQFLIDFGVALPPLMLCPCEHTDDRTVVVVLNEIRADVFTLHFDMLRRVIPG
HHHHHHHCCCEEEEHHHHCCHHEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCC
DRPCPPDVTLHQEQEAVWAALDDRERLLATGCVLRPAVDELYHCFAVMLTHHVNEFFGVQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ETKHLLDQMESHAPDLLKEVLRHATVQRIAELLQRLLMERISIRHLKLIMEAMALWAPRE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KDVSALVEHVRCALARYICHQFAADNLLRVIMLSSEVEETLRDSLHTTSAGTFLNLGPQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHH
SEELMELFTSALESLPIAQRDIVLLAAADIRRFIKSLIQHRFRDLEVLSFGELTESVTVN
HHHHHHHHHHHHHHCCCCHHCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VIKTI
HHHCC
>Mature Secondary Structure
MLNRFLNHIYYRPELLILVLVITIIFMIIIPLPAYLVDFLIGLNIVIAMLVFIGAFYIDR
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSFSTFPAVLLITTLFRLALTISTSRLILTDADAGEIIATFGQFVIGDNLVVGFVIFAI
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHH
VTVVQFIVITKGSERVAEVAARFCLDGMPGKQMSIDADLRGGVIDAEGARQRRSVLERES
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCHHHHHHHHHHHH
QLYGAFDGAMKFIKGDAIASIIVAFVNFIGGIAVGMNQHHMDLSQALSTFTLLTIGDGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHH
GQIPALLISISAGLIVTRVNGDGDNLGRNIMQQLLGNPFVLLVTAVLALSIGMLPGFPLP
HHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
VFVMLAMALGTLLLMRQRQTRVVPLPAAADYAGGYPERIMPEALAVILQVSRANYARLEK
HHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
EQLCERLRGQFLIDFGVALPPLMLCPCEHTDDRTVVVVLNEIRADVFTLHFDMLRRVIPG
HHHHHHHCCCEEEEHHHHCCHHEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCC
DRPCPPDVTLHQEQEAVWAALDDRERLLATGCVLRPAVDELYHCFAVMLTHHVNEFFGVQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ETKHLLDQMESHAPDLLKEVLRHATVQRIAELLQRLLMERISIRHLKLIMEAMALWAPRE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KDVSALVEHVRCALARYICHQFAADNLLRVIMLSSEVEETLRDSLHTTSAGTFLNLGPQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHH
SEELMELFTSALESLPIAQRDIVLLAAADIRRFIKSLIQHRFRDLEVLSFGELTESVTVN
HHHHHHHHHHHHHHCCCCHHCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VIKTI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]