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The map label for this gene is spaR [H]

Identifier: 85060060

GI number: 85060060

Start: 3588560

End: 3589354

Strand: Reverse

Name: spaR [H]

Synonym: SG2082

Alternate gene names: 85060060

Gene position: 3589354-3588560 (Counterclockwise)

Preceding gene: 85060061

Following gene: 85060059

Centisome position: 86.05

GC content: 53.84

Gene sequence:

>795_bases
ATGATCTTGCCACTGTGGTCTTCCCTGTTTGAATGGCTGATTACCCTAGCGGTCGTGTCGGCGCGCATTACGCCGGCGTT
TTTCCTGTTGCCGTTTTTTAGCGCCAGCGTGCTCAGTCTTACCGTTCGCACACCGGTAATTTTTTTTATCGGCGCAGCTT
TGTGGCCTTATTCCTTCGGCGCCATGGCGTCGCTCGACGGTGCACGGATAGCAGACATCCTGCTGCGCGAGGTGGCGATC
GGTCTGCTATTGGCAATCCTGCTGGCGCTACCGTTTTGGGTTATGCATGGGCTGGGGGCGCTGATTGACTATCAGCGCGG
CGCCTTACTCAGCAGCGCCTATGATCCTATCAGCGGCGTCGATACCTCGGAACTGGCAAATTTGTTCAATCTGTTTTTTG
CCGCCGTGTTCCTGCAGGGGGGCGGACTGACTTTGTTACTTGAGGTTTTTCTCGGCAGTTATCAACTGTGCGATCCCCTA
GAGCCCTCCCTACCATCCCTCGCCAAGGTGACAACCTTGTTGCAGACGATGGCGACACGCATCCTGATCCTGTCGAGTCC
CGTTTTGGTGGTGCTGTTGCTCATCGAGATTTCGCTGGGTCTGCTTTCACGCTTCGCGCCGCAAATGAATGCCTTTGCCA
TCGCTTTAACGCTTAAAAGCGGCGTGACCTTCTTTATTATTTTGATCTATTTCGCGCCGCTGTTGCCTGAGATATTTCGT
CAATATTGGCTGTTGCCCTCTCAATTGGAGATATGGCTGAGTAGCGGGCTATCGCCTGGGGAGGAGAATGAGTAA

Upstream 100 bases:

>100_bases
TGTCACCCTGTGTCTGTTTCTGCTCTCGGGTTGGTATGGCGAAACGCTGCTGCAGTTTAGCCATGAAGTCATAAGGATGG
CGTTAGGCCGCTCCTGACCG

Downstream 100 bases:

>100_bases
TAAAACCGAGAAGCCGACGCCTAAGCGCCTGCGCGACGCTGCTAAAAAAGGGCAAGCCTTCAAATCCCGCGACGTCATCA
TTGCCTGCATGATGTTATGC

Product: type III secretion apparatus SpaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MILPLWSSLFEWLITLAVVSARITPAFFLLPFFSASVLSLTVRTPVIFFIGAALWPYSFGAMASLDGARIADILLREVAI
GLLLAILLALPFWVMHGLGALIDYQRGALLSSAYDPISGVDTSELANLFNLFFAAVFLQGGGLTLLLEVFLGSYQLCDPL
EPSLPSLAKVTTLLQTMATRILILSSPVLVVLLLIEISLGLLSRFAPQMNAFAIALTLKSGVTFFIILIYFAPLLPEIFR
QYWLLPSQLEIWLSSGLSPGEENE

Sequences:

>Translated_264_residues
MILPLWSSLFEWLITLAVVSARITPAFFLLPFFSASVLSLTVRTPVIFFIGAALWPYSFGAMASLDGARIADILLREVAI
GLLLAILLALPFWVMHGLGALIDYQRGALLSSAYDPISGVDTSELANLFNLFFAAVFLQGGGLTLLLEVFLGSYQLCDPL
EPSLPSLAKVTTLLQTMATRILILSSPVLVVLLLIEISLGLLSRFAPQMNAFAIALTLKSGVTFFIILIYFAPLLPEIFR
QYWLLPSQLEIWLSSGLSPGEENE
>Mature_264_residues
MILPLWSSLFEWLITLAVVSARITPAFFLLPFFSASVLSLTVRTPVIFFIGAALWPYSFGAMASLDGARIADILLREVAI
GLLLAILLALPFWVMHGLGALIDYQRGALLSSAYDPISGVDTSELANLFNLFFAAVFLQGGGLTLLLEVFLGSYQLCDPL
EPSLPSLAKVTTLLQTMATRILILSSPVLVVLLLIEISLGLLSRFAPQMNAFAIALTLKSGVTFFIILIYFAPLLPEIFR
QYWLLPSQLEIWLSSGLSPGEENE

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002010
- InterPro:   IPR006304 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 28856; Mature: 28856

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPLWSSLFEWLITLAVVSARITPAFFLLPFFSASVLSLTVRTPVIFFIGAALWPYSFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AMASLDGARIADILLREVAIGLLLAILLALPFWVMHGLGALIDYQRGALLSSAYDPISGV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
DTSELANLFNLFFAAVFLQGGGLTLLLEVFLGSYQLCDPLEPSLPSLAKVTTLLQTMATR
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ILILSSPVLVVLLLIEISLGLLSRFAPQMNAFAIALTLKSGVTFFIILIYFAPLLPEIFR
HHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QYWLLPSQLEIWLSSGLSPGEENE
HHCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MILPLWSSLFEWLITLAVVSARITPAFFLLPFFSASVLSLTVRTPVIFFIGAALWPYSFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AMASLDGARIADILLREVAIGLLLAILLALPFWVMHGLGALIDYQRGALLSSAYDPISGV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
DTSELANLFNLFFAAVFLQGGGLTLLLEVFLGSYQLCDPLEPSLPSLAKVTTLLQTMATR
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ILILSSPVLVVLLLIEISLGLLSRFAPQMNAFAIALTLKSGVTFFIILIYFAPLLPEIFR
HHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QYWLLPSQLEIWLSSGLSPGEENE
HHCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609 [H]