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The map label for this gene is speB

Identifier: 85059995

GI number: 85059995

Start: 3476570

End: 3477493

Strand: Reverse

Name: speB

Synonym: SG2017

Alternate gene names: 85059995

Gene position: 3477493-3476570 (Counterclockwise)

Preceding gene: 85059996

Following gene: 85059993

Centisome position: 83.37

GC content: 58.66

Gene sequence:

>924_bases
ATGACGACCCTGGGTCATAATTACGATAACTCGCTGGTATCGAATGCTTTTGGTTTCTTGCGTTTGCCGCTGGAATTCAA
CCCATATGCCACGGACGCCGACTGGGTCATCACCGGTATTCCGTTCGATATGGCCACCTCCGGACGTGCCGGCTGCCGGC
ACGGGCCCGCCGCGATACGCCAGGTTTCCACCAACCTGGCCTGGGAAGGCTGCCGTTGGCCATGGGATTTCGATGTGCGT
AAGCGCTTGAAAGTGGTCGATTGCGGCGATCTGGTGTATGAGTTCGGCGATGCGCAGGATTTTTGCGATAAATTGCAGGA
CCACGCCGAGCGGCTGCTGGCGGCCGGCAAGCGGATGCTGTCGTTCGGCGGCGATCACTTCGTTACCCTGCCGTTGCTGT
GCGCCCACGCCAAGCACTTTGGCAAAATGGCGCTGGTGCATTTTGACGCTCACACCGATACCTATGCCAACGGCAGCAAG
TTCGATCATGGCTCCATGTTTTATCATGCGCCAAACGAAGGGTTAATCAGCCCCGCGCATTCTGTGCAGATAGGCATCCG
CACCGAGTTTGAACGCGATAACGGTTTCACCGTGCTGGATGCGGGACAGGTTAATGACCGCAGCGTTGATGACATCCTGG
CGCAGGTGAAGCAGATTGTGGGTAACCTGCCGGTCTATTTGACCTTTGATATCGACTGTCTCGATCCTTCGGCGGCGCCC
GGCACCGGTACGCCGGTTATCGGCGGCCTGACCAGCGATCGGGCGTTAAAGCTGGTGCGCGGGCTGCAACCGTTGAATAT
CGTTGGTATGGATATCGTCGAGGTCGCGCCGGCCTACGATCAGGCGCAGATTACCGCGCTGGTCGCCGCCACGCTGGCGC
TGGAAATGCTTTACATCCAGGGTGCCAAGCGGGGCGACGACTGA

Upstream 100 bases:

>100_bases
CTGGATGCTGGATTGCAAAGTGAATTCCTGGAGGAATTCGAGGCGGGCCTGTACGGTTACACTTATCTGGAAGATGAATA
ACGTTAAGTAAGGAATGAAG

Downstream 100 bases:

>100_bases
CGGGAAAGGCGGTGTGCTGGATAACCCCAGCGATTTTGCCAGCACGCGCCAAGGGTCCGCCAGACGCGGGACTTGCGCGA
CGTCCACTTCTGCGCCCGCA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTTLGHNYDNSLVSNAFGFLRLPLEFNPYATDADWVITGIPFDMATSGRAGCRHGPAAIRQVSTNLAWEGCRWPWDFDVR
KRLKVVDCGDLVYEFGDAQDFCDKLQDHAERLLAAGKRMLSFGGDHFVTLPLLCAHAKHFGKMALVHFDAHTDTYANGSK
FDHGSMFYHAPNEGLISPAHSVQIGIRTEFERDNGFTVLDAGQVNDRSVDDILAQVKQIVGNLPVYLTFDIDCLDPSAAP
GTGTPVIGGLTSDRALKLVRGLQPLNIVGMDIVEVAPAYDQAQITALVAATLALEMLYIQGAKRGDD

Sequences:

>Translated_307_residues
MTTLGHNYDNSLVSNAFGFLRLPLEFNPYATDADWVITGIPFDMATSGRAGCRHGPAAIRQVSTNLAWEGCRWPWDFDVR
KRLKVVDCGDLVYEFGDAQDFCDKLQDHAERLLAAGKRMLSFGGDHFVTLPLLCAHAKHFGKMALVHFDAHTDTYANGSK
FDHGSMFYHAPNEGLISPAHSVQIGIRTEFERDNGFTVLDAGQVNDRSVDDILAQVKQIVGNLPVYLTFDIDCLDPSAAP
GTGTPVIGGLTSDRALKLVRGLQPLNIVGMDIVEVAPAYDQAQITALVAATLALEMLYIQGAKRGDD
>Mature_306_residues
TTLGHNYDNSLVSNAFGFLRLPLEFNPYATDADWVITGIPFDMATSGRAGCRHGPAAIRQVSTNLAWEGCRWPWDFDVRK
RLKVVDCGDLVYEFGDAQDFCDKLQDHAERLLAAGKRMLSFGGDHFVTLPLLCAHAKHFGKMALVHFDAHTDTYANGSKF
DHGSMFYHAPNEGLISPAHSVQIGIRTEFERDNGFTVLDAGQVNDRSVDDILAQVKQIVGNLPVYLTFDIDCLDPSAAPG
TGTPVIGGLTSDRALKLVRGLQPLNIVGMDIVEVAPAYDQAQITALVAATLALEMLYIQGAKRGDD

Specific function: Catalyzes the formation of putrescine from agmatine

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily

Homologues:

Organism=Homo sapiens, GI37537722, Length=290, Percent_Identity=42.4137931034483, Blast_Score=211, Evalue=6e-55,
Organism=Escherichia coli, GI1789306, Length=306, Percent_Identity=83.3333333333333, Blast_Score=519, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI71996843, Length=295, Percent_Identity=24.7457627118644, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEB_SODGM (Q2NRD3)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455697.1
- ProteinModelPortal:   Q2NRD3
- SMR:   Q2NRD3
- STRING:   Q2NRD3
- GeneID:   3868796
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2017
- NMPDR:   fig|343509.6.peg.4350
- eggNOG:   COG0010
- HOGENOM:   HBG391953
- OMA:   TNLAWEG
- PhylomeDB:   Q2NRD3
- ProtClustDB:   PRK02190
- BioCyc:   SGLO343509:SG2017-MONOMER
- HAMAP:   MF_01418
- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358
- TIGRFAMs:   TIGR01230

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.11

Molecular weight: Translated: 33526; Mature: 33395

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLGHNYDNSLVSNAFGFLRLPLEFNPYATDADWVITGIPFDMATSGRAGCRHGPAAIR
CCCCCCCCCHHHHHCCCCEEEECEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEGCRWPWDFDVRKRLKVVDCGDLVYEFGDAQDFCDKLQDHAERLLAAGKRML
HHHHCCCCCCCCCCCCCCHHHCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLCAHAKHFGKMALVHFDAHTDTYANGSKFDHGSMFYHAPNEGLISPAH
HCCCCCEEHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
SVQIGIRTEFERDNGFTVLDAGQVNDRSVDDILAQVKQIVGNLPVYLTFDIDCLDPSAAP
EEEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC
GTGTPVIGGLTSDRALKLVRGLQPLNIVGMDIVEVAPAYDQAQITALVAATLALEMLYIQ
CCCCCEECCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GAKRGDD
CCCCCCC
>Mature Secondary Structure 
TTLGHNYDNSLVSNAFGFLRLPLEFNPYATDADWVITGIPFDMATSGRAGCRHGPAAIR
CCCCCCCCHHHHHCCCCEEEECEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEGCRWPWDFDVRKRLKVVDCGDLVYEFGDAQDFCDKLQDHAERLLAAGKRML
HHHHCCCCCCCCCCCCCCHHHCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLCAHAKHFGKMALVHFDAHTDTYANGSKFDHGSMFYHAPNEGLISPAH
HCCCCCEEHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
SVQIGIRTEFERDNGFTVLDAGQVNDRSVDDILAQVKQIVGNLPVYLTFDIDCLDPSAAP
EEEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC
GTGTPVIGGLTSDRALKLVRGLQPLNIVGMDIVEVAPAYDQAQITALVAATLALEMLYIQ
CCCCCEECCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GAKRGDD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA