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The map label for this gene is speA [H]

Identifier: 85059996

GI number: 85059996

Start: 3477513

End: 3479435

Strand: Reverse

Name: speA [H]

Synonym: SG2018

Alternate gene names: 85059996

Gene position: 3479435-3477513 (Counterclockwise)

Preceding gene: 85060003

Following gene: 85059995

Centisome position: 83.42

GC content: 55.85

Gene sequence:

>1923_bases
TTGCGCTCAATGCAGGAGGTAGCCATGAACGACAGCGACGCCAGTAAAATGCTGCGAACCTATAATGTCACGTACTGGGG
CAATAACTACTATGACGTTAATGAGTTGGGTCATATCAGCGTTTGCCCGGATCCGGACTTTCCCGAAGCGTGCGTCGATC
TGGCCGAATTGGTGAAACAGCGTCAAGCCGACGGCCAGCGTCTGCCGGCGCTGTTCTGTTTTCCGCAGATCCTGCAACAC
CGTTTGCGTTCCATTAACGCCGCTTTCCAGCGCGCGCGGGATTCCTTTGGCTATCAGGGCGGCTATTTTCTGGTTTACCC
GATTAAGGTTAACCAGCACCGCCGCGTTATCGAGTCACTGGTCAACTCCGGTGAGCCCCTGGGTCTGGAGGCCGGCTCCA
AGGCAGAGCTGATGGCGGTGATCGCTCATGCCGGCATGACCCGCACGGTGATTGTCTGCAACGGCTATAAAGATCGGGAA
TATATTCGTCTGGCGCTTATCGGTGAGAAGATCGGCCATAAAGTCTATCTGGTGATTGAAAAACTTTCCGAAATTACACT
GGTGCTTGAAGAGGCAGAACGGCTGAATGTCGTACCGCGCCTCGGCGTACGCACCCGTCTGGCCTCTCAGGGCTCCGGCA
AATGGCAATCCAGCGGCGGCGAGAAGTCCAAATTCGGTCTGGCGGCGGCGCAGGTGCTGCAACTGGTCGATCTACTGCGT
GCGAAAGGGCGGTTGGACAGTCTGCAATTACTGCATTTCCATTTGGGTTCCCAATTGTCGAATATTCGCGATATCGCTTC
CGGCGTACGTGAGTCGGCGCGTTTTTATGTTGAATTGCATAAACTGGGGGTCCGTATTGAATGTTTCGACGTCGGCGGCG
GTTTGGGGGTCGATTATGAAGGCACCCGTTCCCAATCCGACGGCTCGGCCAATTATGGCCTGAACGAGTATGCCAACAAT
GTCATTTGGGGCATCGGCGATGCCTGTAATGAATACGGCCTGCCGCACCCAACGGTCATTACCGAGTCTGGACGGGCGGT
AACGGCGCATCATACCGTGCTGGTGTCGAATGTTATCGGCGTGGAGCGCAATGAATTCAGCGAACCACACCCGCCGGAAG
CGGACGCCCCGCGCGCGCTGGAAAGCCTGTGGCAGACCTGGCAGGAGATGCAAGAGCCGCGCAACCGCCGTTCGTTACGT
GAATGGTTGCACGACAGCCAGATGGACCTGCATGATGTTCATACACAATATACTCACGGTATGCTGGATTTGACGCAGCG
TGCCTGGGCGGAGCAGCTGTATCTCAGCATTTGCCGCTTGATCCAGACGCAGCTCGACCCTAGTAATCGCGCCCACCGGC
CGATTATCGATGAATTGCAGGAACGCATGGCGGATAAGCTGTACGTGAACTTCTCGCTGTTCCAATCGATGCCGGACGCC
TGGGGTATCGACCAATTGTTCCCGGTTCTGCCGCTGGCGGGACTGGATAAACCGCCGGAAGGGCGTGCGGTACTGTTGGA
TATTACCTGTGACTCTGACGGTACCATTGATCATTATATTGATGGCGACGGCATCGCCACCACCATGCCGATGCCGCCCT
ATGATGCCGATAACCCGCCGCCCCTCGGCTTTTTCATGGTGGGCGCCTACCAGGAAATCCTCGGTAACATGCATAATCTG
TTCGGCGATACCGCGGCCGTCGATGTGTATGTGTTCAAGGACGGCAGCATGGAATTGAACGAGTCGGACGAAGGGGATAC
CGTCGCCGATATGCTGCGCTATGTGCAGCTGGATCCCGACGTGTTGCTGACCCGTTTCCGAGACCAGGTGAAAGACACCG
ATCTGGATGCTGGATTGCAAAGTGAATTCCTGGAGGAATTCGAGGCGGGCCTGTACGGTTACACTTATCTGGAAGATGAA
TAA

Upstream 100 bases:

>100_bases
CTTACCCGATGTGGGTCGACAAGCGGGCTTCGCGTCCGGGAGGATGCCGCCATGACTGACTCGCGACCGAACCCGGAGCC
GCGCGGCTCGAAAAGACACT

Downstream 100 bases:

>100_bases
CGTTAAGTAAGGAATGAAGATGACGACCCTGGGTCATAATTACGATAACTCGCTGGTATCGAATGCTTTTGGTTTCTTGC
GTTTGCCGCTGGAATTCAAC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MRSMQEVAMNDSDASKMLRTYNVTYWGNNYYDVNELGHISVCPDPDFPEACVDLAELVKQRQADGQRLPALFCFPQILQH
RLRSINAAFQRARDSFGYQGGYFLVYPIKVNQHRRVIESLVNSGEPLGLEAGSKAELMAVIAHAGMTRTVIVCNGYKDRE
YIRLALIGEKIGHKVYLVIEKLSEITLVLEEAERLNVVPRLGVRTRLASQGSGKWQSSGGEKSKFGLAAAQVLQLVDLLR
AKGRLDSLQLLHFHLGSQLSNIRDIASGVRESARFYVELHKLGVRIECFDVGGGLGVDYEGTRSQSDGSANYGLNEYANN
VIWGIGDACNEYGLPHPTVITESGRAVTAHHTVLVSNVIGVERNEFSEPHPPEADAPRALESLWQTWQEMQEPRNRRSLR
EWLHDSQMDLHDVHTQYTHGMLDLTQRAWAEQLYLSICRLIQTQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDA
WGIDQLFPVLPLAGLDKPPEGRAVLLDITCDSDGTIDHYIDGDGIATTMPMPPYDADNPPPLGFFMVGAYQEILGNMHNL
FGDTAAVDVYVFKDGSMELNESDEGDTVADMLRYVQLDPDVLLTRFRDQVKDTDLDAGLQSEFLEEFEAGLYGYTYLEDE

Sequences:

>Translated_640_residues
MRSMQEVAMNDSDASKMLRTYNVTYWGNNYYDVNELGHISVCPDPDFPEACVDLAELVKQRQADGQRLPALFCFPQILQH
RLRSINAAFQRARDSFGYQGGYFLVYPIKVNQHRRVIESLVNSGEPLGLEAGSKAELMAVIAHAGMTRTVIVCNGYKDRE
YIRLALIGEKIGHKVYLVIEKLSEITLVLEEAERLNVVPRLGVRTRLASQGSGKWQSSGGEKSKFGLAAAQVLQLVDLLR
AKGRLDSLQLLHFHLGSQLSNIRDIASGVRESARFYVELHKLGVRIECFDVGGGLGVDYEGTRSQSDGSANYGLNEYANN
VIWGIGDACNEYGLPHPTVITESGRAVTAHHTVLVSNVIGVERNEFSEPHPPEADAPRALESLWQTWQEMQEPRNRRSLR
EWLHDSQMDLHDVHTQYTHGMLDLTQRAWAEQLYLSICRLIQTQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDA
WGIDQLFPVLPLAGLDKPPEGRAVLLDITCDSDGTIDHYIDGDGIATTMPMPPYDADNPPPLGFFMVGAYQEILGNMHNL
FGDTAAVDVYVFKDGSMELNESDEGDTVADMLRYVQLDPDVLLTRFRDQVKDTDLDAGLQSEFLEEFEAGLYGYTYLEDE
>Mature_640_residues
MRSMQEVAMNDSDASKMLRTYNVTYWGNNYYDVNELGHISVCPDPDFPEACVDLAELVKQRQADGQRLPALFCFPQILQH
RLRSINAAFQRARDSFGYQGGYFLVYPIKVNQHRRVIESLVNSGEPLGLEAGSKAELMAVIAHAGMTRTVIVCNGYKDRE
YIRLALIGEKIGHKVYLVIEKLSEITLVLEEAERLNVVPRLGVRTRLASQGSGKWQSSGGEKSKFGLAAAQVLQLVDLLR
AKGRLDSLQLLHFHLGSQLSNIRDIASGVRESARFYVELHKLGVRIECFDVGGGLGVDYEGTRSQSDGSANYGLNEYANN
VIWGIGDACNEYGLPHPTVITESGRAVTAHHTVLVSNVIGVERNEFSEPHPPEADAPRALESLWQTWQEMQEPRNRRSLR
EWLHDSQMDLHDVHTQYTHGMLDLTQRAWAEQLYLSICRLIQTQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDA
WGIDQLFPVLPLAGLDKPPEGRAVLLDITCDSDGTIDHYIDGDGIATTMPMPPYDADNPPPLGFFMVGAYQEILGNMHNL
FGDTAAVDVYVFKDGSMELNESDEGDTVADMLRYVQLDPDVLLTRFRDQVKDTDLDAGLQSEFLEEFEAGLYGYTYLEDE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=640, Percent_Identity=84.375, Blast_Score=1140, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71852; Mature: 71852

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSMQEVAMNDSDASKMLRTYNVTYWGNNYYDVNELGHISVCPDPDFPEACVDLAELVKQ
CCCHHHHHCCCCHHHHHHHHEEEEEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHH
RQADGQRLPALFCFPQILQHRLRSINAAFQRARDSFGYQGGYFLVYPIKVNQHRRVIESL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHH
VNSGEPLGLEAGSKAELMAVIAHAGMTRTVIVCNGYKDREYIRLALIGEKIGHKVYLVIE
HCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEEEEHHHHCCEEEEHHH
KLSEITLVLEEAERLNVVPRLGVRTRLASQGSGKWQSSGGEKSKFGLAAAQVLQLVDLLR
HHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AKGRLDSLQLLHFHLGSQLSNIRDIASGVRESARFYVELHKLGVRIECFDVGGGLGVDYE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
GTRSQSDGSANYGLNEYANNVIWGIGDACNEYGLPHPTVITESGRAVTAHHTVLVSNVIG
CCCCCCCCCCCCCHHHHHCCEEECCCHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHC
VERNEFSEPHPPEADAPRALESLWQTWQEMQEPRNRRSLREWLHDSQMDLHDVHTQYTHG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MLDLTQRAWAEQLYLSICRLIQTQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHCCCCC
WGIDQLFPVLPLAGLDKPPEGRAVLLDITCDSDGTIDHYIDGDGIATTMPMPPYDADNPP
CCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEECCCCCCCCCCCC
PLGFFMVGAYQEILGNMHNLFGDTAAVDVYVFKDGSMELNESDEGDTVADMLRYVQLDPD
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEECCCCCCCCHHHHHHHHHHCCHH
VLLTRFRDQVKDTDLDAGLQSEFLEEFEAGLYGYTYLEDE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MRSMQEVAMNDSDASKMLRTYNVTYWGNNYYDVNELGHISVCPDPDFPEACVDLAELVKQ
CCCHHHHHCCCCHHHHHHHHEEEEEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHH
RQADGQRLPALFCFPQILQHRLRSINAAFQRARDSFGYQGGYFLVYPIKVNQHRRVIESL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHH
VNSGEPLGLEAGSKAELMAVIAHAGMTRTVIVCNGYKDREYIRLALIGEKIGHKVYLVIE
HCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEEEEHHHHCCEEEEHHH
KLSEITLVLEEAERLNVVPRLGVRTRLASQGSGKWQSSGGEKSKFGLAAAQVLQLVDLLR
HHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AKGRLDSLQLLHFHLGSQLSNIRDIASGVRESARFYVELHKLGVRIECFDVGGGLGVDYE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
GTRSQSDGSANYGLNEYANNVIWGIGDACNEYGLPHPTVITESGRAVTAHHTVLVSNVIG
CCCCCCCCCCCCCHHHHHCCEEECCCHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHC
VERNEFSEPHPPEADAPRALESLWQTWQEMQEPRNRRSLREWLHDSQMDLHDVHTQYTHG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MLDLTQRAWAEQLYLSICRLIQTQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHCCCCC
WGIDQLFPVLPLAGLDKPPEGRAVLLDITCDSDGTIDHYIDGDGIATTMPMPPYDADNPP
CCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEECCCCCCCCCCCC
PLGFFMVGAYQEILGNMHNLFGDTAAVDVYVFKDGSMELNESDEGDTVADMLRYVQLDPD
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEECCCCCCCCHHHHHHHHHHCCHH
VLLTRFRDQVKDTDLDAGLQSEFLEEFEAGLYGYTYLEDE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]