Click here to switch to the map view.

The map label for this gene is rpiA

Identifier: 85059988

GI number: 85059988

Start: 3467055

End: 3467711

Strand: Reverse

Name: rpiA

Synonym: SG2010

Alternate gene names: 85059988

Gene position: 3467711-3467055 (Counterclockwise)

Preceding gene: 85059990

Following gene: 85059987

Centisome position: 83.14

GC content: 58.75

Gene sequence:

>657_bases
ATGACGCAGGATGAACTGAAAAAAGCGGTTGGCTGGGCCGCGCTGAAATATGTCCGGCTTGGCACGATTGTGGGCGTGGG
GACCGGCTCTACCGCGGCGCATTTTATCGACGCGCTGGCCTCCGTCAGGCACCAAATCGACGGGGCGGTATCCAGCTCCG
AGGCATCGTCTGCCAAATTGCAAAGCCTGGGCATCCCGTTATTCGACCTGAATGAGGTGGATTCTCTGGATATTTACGTC
GATGGCGCCGATGAGATTAACGGCAGCATGCAGATGATTAAAGGCGGGGGGGCTGCGCTGACCCGCGAAAAAATCATCGC
CGCCGTGGCGCGTAAGTTTATCTGTATCGCCGATTCCAGCAAGCTGGTGGACGTGCTCGGCACCTTTCCGCTTCCGGTGG
AGGTGATCCCCATGGCTCGCGCCTGGGTGGCTCGCGAATTGGTTCGCCTGGGCGGTGCACCGGTCTATCGTCAGGGCGTG
GTGACCGACAACGGCAATATCATTCTGGATGTCCACAATCTGGCCATTATGGATGCGGTGGCGCTTGAGGAGCAAATTAA
CAATATCCCAGGCGTCGTTACCGTTGGCCTGTTCGCGCGCCGCGGCGCCGATGTGGCGCTTATCGGCAGCGAGCAGGGCG
TCAAAATCATTGGCTAA

Upstream 100 bases:

>100_bases
GGCCTCACGAGGCCGAGGTTGTGGTAATCTTCACGCCATTGCCGCGAAGATTGATTTATACTGGCGCCCACACAGAATTG
CACACGGGCAAAAATAGACC

Downstream 100 bases:

>100_bases
ATCGACCGTCGGCACGCGTTTAACCCTGCCGCCTATGTTAATAAAAATCCGATAATATGTTTTATTTTCCCACCCTGAAT
TTAGTGATTAATTTCACGCT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDELKKAVGWAALKYVRLGTIVGVGTGSTAAHFIDALASVRHQIDGAVSSSEASSAKLQSLGIPLFDLNEVDSLDIYV
DGADEINGSMQMIKGGGAALTREKIIAAVARKFICIADSSKLVDVLGTFPLPVEVIPMARAWVARELVRLGGAPVYRQGV
VTDNGNIILDVHNLAIMDAVALEEQINNIPGVVTVGLFARRGADVALIGSEQGVKIIG

Sequences:

>Translated_218_residues
MTQDELKKAVGWAALKYVRLGTIVGVGTGSTAAHFIDALASVRHQIDGAVSSSEASSAKLQSLGIPLFDLNEVDSLDIYV
DGADEINGSMQMIKGGGAALTREKIIAAVARKFICIADSSKLVDVLGTFPLPVEVIPMARAWVARELVRLGGAPVYRQGV
VTDNGNIILDVHNLAIMDAVALEEQINNIPGVVTVGLFARRGADVALIGSEQGVKIIG
>Mature_217_residues
TQDELKKAVGWAALKYVRLGTIVGVGTGSTAAHFIDALASVRHQIDGAVSSSEASSAKLQSLGIPLFDLNEVDSLDIYVD
GADEINGSMQMIKGGGAALTREKIIAAVARKFICIADSSKLVDVLGTFPLPVEVIPMARAWVARELVRLGGAPVYRQGVV
TDNGNIILDVHNLAIMDAVALEEQINNIPGVVTVGLFARRGADVALIGSEQGVKIIG

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=210, Percent_Identity=38.5714285714286, Blast_Score=110, Evalue=9e-25,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=79.2626728110599, Blast_Score=347, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=37.1428571428571, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324669, Length=217, Percent_Identity=32.7188940092166, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281364072, Length=194, Percent_Identity=34.5360824742268, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_SODGM (Q2NRE0)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455690.1
- ProteinModelPortal:   Q2NRE0
- SMR:   Q2NRE0
- STRING:   Q2NRE0
- GeneID:   3868789
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2010
- NMPDR:   fig|343509.6.peg.4339
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- PhylomeDB:   Q2NRE0
- ProtClustDB:   PRK00702
- BioCyc:   SGLO343509:SG2010-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 22860; Mature: 22729

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKKAVGWAALKYVRLGTIVGVGTGSTAAHFIDALASVRHQIDGAVSSSEASSAKL
CCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
QSLGIPLFDLNEVDSLDIYVDGADEINGSMQMIKGGGAALTREKIIAAVARKFICIADSS
HHCCCCEEECCCCCCEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEECCC
KLVDVLGTFPLPVEVIPMARAWVARELVRLGGAPVYRQGVVTDNGNIILDVHNLAIMDAV
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEECCEEECCCCEEEEECCHHHHHHH
ALEEQINNIPGVVTVGLFARRGADVALIGSEQGVKIIG
HHHHHHCCCCCCEEHHHHHHCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TQDELKKAVGWAALKYVRLGTIVGVGTGSTAAHFIDALASVRHQIDGAVSSSEASSAKL
CHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
QSLGIPLFDLNEVDSLDIYVDGADEINGSMQMIKGGGAALTREKIIAAVARKFICIADSS
HHCCCCEEECCCCCCEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEECCC
KLVDVLGTFPLPVEVIPMARAWVARELVRLGGAPVYRQGVVTDNGNIILDVHNLAIMDAV
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEECCEEECCCCEEEEECCHHHHHHH
ALEEQINNIPGVVTVGLFARRGADVALIGSEQGVKIIG
HHHHHHCCCCCCEEHHHHHHCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA