Click here to switch to the map view.

The map label for this gene is frr

Identifier: 85059918

GI number: 85059918

Start: 3345163

End: 3345720

Strand: Reverse

Name: frr

Synonym: SG1940

Alternate gene names: 85059918

Gene position: 3345720-3345163 (Counterclockwise)

Preceding gene: 85059919

Following gene: 85059917

Centisome position: 80.21

GC content: 57.17

Gene sequence:

>558_bases
GTGATTAATGAAATCCGTAAAGATGCCGAGATTCGCATGGAAAAATGCGTCGACGCGTTCAAAAGCCACATCAGCAAAGT
CCGTACGGGCCGCGCTTCCCCGAGCCTGCTTGACGGTATTCAGATCGACTATTACGGCTTGCTGACGCCGCTGCGCCAGC
TGGCCAATATTATTGCCGAGGATTCCCGTACCCTGGCCATCACCGTCTTTGACCGCACGTTGGCACCGGCGGTGGAAAAG
GCCATCATGGCCTCCGATCTGGGGCTAAATCCGTCTTCCGCCGGCACGGTGATTCGCGTACCGCTGCCGCCGCTGACCGA
AGAGCGCCGCCGCGACCTGATAAAGGTAGTGCGCGCCGAGGCGGAACAGGGCAGGGTATCGGTGCGCAATGTCCGCCGCG
ATGCCAACGACAAGGTGAAGGCGCTGTTGAAAGACAAAACCATCGGTGAAGATGAAGATCGCCGCTCGCAGGACGAGATC
CAGAAGCTGACCGACGCCTGGATCAAAAAGCTTGATAGCGCCCTGGCGGAAAAAGAAGCGGAATTAATGGAAATTTAA

Upstream 100 bases:

>100_bases
GTGATAAAGAAGGCACCTTGATTACCAAGTAATGCATAACGGGGCCTGGCAACCAACGGCCACGGTCCGCCCGGATAACC
AAGTCTCAAGGGTTCGCAAC

Downstream 100 bases:

>100_bases
TCCCCCCCCGGCGAAATGAAAACGCCGTAGCGGCGCCTCCCTGGCGGAGGTGCTGTCGCTGCGGCGTTTTTTTGTGTAAG
CCGCCATAGACAAAACGGAG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIRKDAEIRMEKCVDAFKSHISKVRTGRASPSLLDGIQIDYYGLLTPLRQLANIIAEDSRTLAITVFDRTLAPAVEK
AIMASDLGLNPSSAGTVIRVPLPPLTEERRRDLIKVVRAEAEQGRVSVRNVRRDANDKVKALLKDKTIGEDEDRRSQDEI
QKLTDAWIKKLDSALAEKEAELMEI

Sequences:

>Translated_185_residues
MINEIRKDAEIRMEKCVDAFKSHISKVRTGRASPSLLDGIQIDYYGLLTPLRQLANIIAEDSRTLAITVFDRTLAPAVEK
AIMASDLGLNPSSAGTVIRVPLPPLTEERRRDLIKVVRAEAEQGRVSVRNVRRDANDKVKALLKDKTIGEDEDRRSQDEI
QKLTDAWIKKLDSALAEKEAELMEI
>Mature_185_residues
MINEIRKDAEIRMEKCVDAFKSHISKVRTGRASPSLLDGIQIDYYGLLTPLRQLANIIAEDSRTLAITVFDRTLAPAVEK
AIMASDLGLNPSSAGTVIRVPLPPLTEERRRDLIKVVRAEAEQGRVSVRNVRRDANDKVKALLKDKTIGEDEDRRSQDEI
QKLTDAWIKKLDSALAEKEAELMEI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=32.183908045977, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI291042689, Length=136, Percent_Identity=33.8235294117647, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=76.7567567567568, Blast_Score=297, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=29.8850574712644, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SODGM (Q2NRL0)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455620.1
- ProteinModelPortal:   Q2NRL0
- SMR:   Q2NRL0
- STRING:   Q2NRL0
- GeneID:   3867852
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1940
- NMPDR:   fig|343509.6.peg.4194
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q2NRL0
- ProtClustDB:   PRK00083
- BioCyc:   SGLO343509:SG1940-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20762; Mature: 20762

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIRKDAEIRMEKCVDAFKSHISKVRTGRASPSLLDGIQIDYYGLLTPLRQLANIIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHC
DSRTLAITVFDRTLAPAVEKAIMASDLGLNPSSAGTVIRVPLPPLTEERRRDLIKVVRAE
CCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEQGRVSVRNVRRDANDKVKALLKDKTIGEDEDRRSQDEIQKLTDAWIKKLDSALAEKEA
HHCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMEI
HHHCC
>Mature Secondary Structure
MINEIRKDAEIRMEKCVDAFKSHISKVRTGRASPSLLDGIQIDYYGLLTPLRQLANIIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHC
DSRTLAITVFDRTLAPAVEKAIMASDLGLNPSSAGTVIRVPLPPLTEERRRDLIKVVRAE
CCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEQGRVSVRNVRRDANDKVKALLKDKTIGEDEDRRSQDEIQKLTDAWIKKLDSALAEKEA
HHCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMEI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA