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The map label for this gene is era

Identifier: 85059764

GI number: 85059764

Start: 3050734

End: 3051639

Strand: Reverse

Name: era

Synonym: SG1786

Alternate gene names: 85059764

Gene position: 3051639-3050734 (Counterclockwise)

Preceding gene: 85059765

Following gene: 85059763

Centisome position: 73.16

GC content: 52.65

Gene sequence:

>906_bases
ATGAGCGAACAGACGACCTATTGTGGGTTTGTGGCGATAGTGGGCCGGCCGAACGTCGGTAAATCCACGCTGCTGAATCA
GTTTTTAGGGCAGAAGGTCTCTATTACTTCGCGCAAACCGCAAACCACCCGCCACCGCATCATGGGGATCCACACCGAAG
GACCATATCAAGCTATCTATGTGGACACGCCGGGACTGCATATTGAAGAGAAACGGGCGATTAACCGGTTGATGAATCGC
GCGGCCAGCAGTTCCATCTGCGACGTGGAGTTGGTGATTTTCGTGGTGGAAGGCACCCACTGGACGCCGGACGATGAGAT
GGTGGTGAACAAACTGCATGACGTTAACTGCCCGGTCGTGTTGGCGATCAACAAGGTAGATAACGTGACTGATAAAGAAC
AACTGCTGCCCCATATGCAGTTCCTCAGTCAGCAAATTTCGTTTCATCACATCGTACCAATCTGCGCCGAGAACGGCATG
AACGTTGAAACCCTGGCCGGGATTGTGCGTAAAGCGCTGCCGGAAGCTGTGCACCATTTTCCGGAAGATTACATTACCGA
CCGTTCCCAACGTTTTATGGCTTCGGAAATTATACGCGAAAAGCTGATGCGTTTTCTGGGCGATGAGCTTCCCTATTCCG
TCACGGTAGAGATTGAGCGTTTTGCCAGCAACGATCGCGGCGGTTACGACATACATGGGCTTATTCTGGTGGAGCGCGAG
GGCCAGAAGAAGATGGTTATCGGCAATAAGGGCAGCAAAATCAAGACCATTAGTATTGAAGCCCGGCAAGATATGGAAGC
CATGTTCGAGACGCGGGTGCATCTGGAACTGTGGGTGAAGGTGAAATCGGGCTGGGCCGATGATGAACGTGCTCTGCGCA
GTCTGGGCTACGTCGACGATCTGTAG

Upstream 100 bases:

>100_bases
AGGTCAGCGGGCTGGCGCAGCCGGTGGTCGGTAATGGCTCAAGCCGTCGTAAAGCCGAGCAGGCCGCGGCGGAGCAGGCA
CTCAAATTGTTGGAGCTTGA

Downstream 100 bases:

>100_bases
GCAACGCTGATGGACGGTTGGCAACGCGCCTTCGTACTCCATGCTCGCCCTTACAGCGAAACCAGCCTGCTTCTGGACTT
TTTCACCGAACAGCAAGGGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSEQTTYCGFVAIVGRPNVGKSTLLNQFLGQKVSITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNR
AASSSICDVELVIFVVEGTHWTPDDEMVVNKLHDVNCPVVLAINKVDNVTDKEQLLPHMQFLSQQISFHHIVPICAENGM
NVETLAGIVRKALPEAVHHFPEDYITDRSQRFMASEIIREKLMRFLGDELPYSVTVEIERFASNDRGGYDIHGLILVERE
GQKKMVIGNKGSKIKTISIEARQDMEAMFETRVHLELWVKVKSGWADDERALRSLGYVDDL

Sequences:

>Translated_301_residues
MSEQTTYCGFVAIVGRPNVGKSTLLNQFLGQKVSITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNR
AASSSICDVELVIFVVEGTHWTPDDEMVVNKLHDVNCPVVLAINKVDNVTDKEQLLPHMQFLSQQISFHHIVPICAENGM
NVETLAGIVRKALPEAVHHFPEDYITDRSQRFMASEIIREKLMRFLGDELPYSVTVEIERFASNDRGGYDIHGLILVERE
GQKKMVIGNKGSKIKTISIEARQDMEAMFETRVHLELWVKVKSGWADDERALRSLGYVDDL
>Mature_300_residues
SEQTTYCGFVAIVGRPNVGKSTLLNQFLGQKVSITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNRA
ASSSICDVELVIFVVEGTHWTPDDEMVVNKLHDVNCPVVLAINKVDNVTDKEQLLPHMQFLSQQISFHHIVPICAENGMN
VETLAGIVRKALPEAVHHFPEDYITDRSQRFMASEIIREKLMRFLGDELPYSVTVEIERFASNDRGGYDIHGLILVEREG
QKKMVIGNKGSKIKTISIEARQDMEAMFETRVHLELWVKVKSGWADDERALRSLGYVDDL

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=323, Percent_Identity=28.4829721362229, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=82.3920265780731, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI87082120, Length=167, Percent_Identity=29.3413173652695, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24646434, Length=304, Percent_Identity=25.3289473684211, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34155; Mature: 34024

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQTTYCGFVAIVGRPNVGKSTLLNQFLGQKVSITSRKPQTTRHRIMGIHTEGPYQAIY
CCCCCEEEEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEECCCCEEEEE
VDTPGLHIEEKRAINRLMNRAASSSICDVELVIFVVEGTHWTPDDEMVVNKLHDVNCPVV
EECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCCEE
LAINKVDNVTDKEQLLPHMQFLSQQISFHHIVPICAENGMNVETLAGIVRKALPEAVHHF
EEEECCCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
PEDYITDRSQRFMASEIIREKLMRFLGDELPYSVTVEIERFASNDRGGYDIHGLILVERE
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEEC
GQKKMVIGNKGSKIKTISIEARQDMEAMFETRVHLELWVKVKSGWADDERALRSLGYVDD
CCEEEEECCCCCEEEEEEECCHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCCCC
L
C
>Mature Secondary Structure 
SEQTTYCGFVAIVGRPNVGKSTLLNQFLGQKVSITSRKPQTTRHRIMGIHTEGPYQAIY
CCCCEEEEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEECCCCEEEEE
VDTPGLHIEEKRAINRLMNRAASSSICDVELVIFVVEGTHWTPDDEMVVNKLHDVNCPVV
EECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCCEE
LAINKVDNVTDKEQLLPHMQFLSQQISFHHIVPICAENGMNVETLAGIVRKALPEAVHHF
EEEECCCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
PEDYITDRSQRFMASEIIREKLMRFLGDELPYSVTVEIERFASNDRGGYDIHGLILVERE
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEEC
GQKKMVIGNKGSKIKTISIEARQDMEAMFETRVHLELWVKVKSGWADDERALRSLGYVDD
CCEEEEECCCCCEEEEEEECCHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA