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The map label for this gene is engA

Identifier: 85059734

GI number: 85059734

Start: 3010637

End: 3012103

Strand: Reverse

Name: engA

Synonym: SG1756

Alternate gene names: 85059734

Gene position: 3012103-3010637 (Counterclockwise)

Preceding gene: 85059735

Following gene: 85059730

Centisome position: 72.21

GC content: 56.44

Gene sequence:

>1467_bases
ATGATACCTGTCGTCGCGCTGGTCGGGCGCCCGAATGTAGGAAAATCCACTCTCTTTAATCGACTAACGCGCACTCGTGA
TGCGCTGGTGGCGGATTTTCCGGGGCTGACGCGTGACCGCAAGTATTGTCGTGCCGAATGGGAAGGCCATGAGTTTATCG
TTATTGATACCGGCGGTATTGATGGCACTGAGGAAGGGGTGGAAACCCGCATGGCCGGTCAGTCGCTGGTGGCGATTGAA
GAGGCCGACATTGTGTTGTTCATGGTAGATGGACGCGCCGGGCTGATGGCGGCCGATAAAGGTATTGCCAGGCATCTGCG
CAGCCGCGAGAAAACCACGGTGATTGTCGCCAATAAAACCGACGGGATCGATGCCGACAGCGCGGTGGGGGATTTTTATT
CCCTGGGCATGGGCGAGATAGTCCCTATTGCCGCCTCGCACGGGCGCGGCATCAACAGCCTGTTGGAGCAGGTTTTGTTG
CCGCTGGTGAGCGATGGTTTGGCGGAGGCGGAGGACGAATTTGCGCCCTGGCCTGACGACGAGGCAGAGGTGCTGGCGCG
GGAAGAAGAAGAGGAGCCTTTTGATCCTCAATCGTTGCCGATAAAGCTTGCGATCGTCGGGCGTCCCAACGTGGGTAAAT
CCACGCTCACCAACCGCATTCTCGGCGAAGAGCGTGTGGTGGTCTATGACATGCCCGGCACTACCCGCGACAGCATATAT
ATTCCCATGGTACGTGACGAGCGGGAGTATGTCCTGATCGATACCGCCGGCGTGCGCAAGCGTGGCAAGGTCACGGAAAC
CGTGGAGAAATTCTCTGTGATCAAAACGCTGCAGGCTATCGAAGATGCCAATGTCGTATTGCTGGTCATCGACGCCCGTG
AAGGCATTTCCGATCAGGATTTGTCGCTGCTGGGCTTTATCCTCAACAGTGGCCGCTCGCTGGTCATTGCGGTCAATAAA
TGGGATGGTCTGTCCAGCGAGACGCGTGACGAAGTGAAAGAGGCGCTGGATCATCGTCTTGGTTTTATCGATTTTGCCCG
CGTGCATTTCATCTCTGCCCTGCACGGCAGTGGCGTCGGCAATCTGTTTGAATCGGTGAATGAAGCCTACCAATGCGCCA
CCAAGCGGGTGAGCACTGCGCTATTGACGCGCATCATGCGCATGGCGGTTGATGAACATCAACCGCCGCTGGTGCGCGGT
CGGCGCGTTAAACCCAAATATGCCCATGCCGGTGGCTACAATCCTCCGATTGTGGTGATCCACGGCACACAGGTTAAAGA
TTTGCCGGATACCTATAAGCGCTATCTGATGAATTATTTCCGCCGCTCGCTGGGGATTATGGGTACGCCGATTCGCATCC
AGTTCAACGAGGGCGCCAACCCCTTCGCCGGGCGGCGCAATACCTTGACACCGACGCAGCTGCGTAAACGCAAGCGGCTG
ATGAGTCATATCAAGAAAAACAAATAA

Upstream 100 bases:

>100_bases
CGCTTCCCGCAACGGCTCCTGACATGTTCAGGAGCCGTTTTGTCTTATATAATCGGTCCTGTTTCGTCTTTGCCGTTTTT
AACCTGATGAGGTTGTAATA

Downstream 100 bases:

>100_bases
GCGTGATGGACATGGCACACTGTGAGATTTGCCAACAGCCGCTGGTTACCGCGGGCAATAAGCTGCATTGTCCCGCCTGC
GGGCAAGACTATCGTGAGTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYCRAEWEGHEFIVIDTGGIDGTEEGVETRMAGQSLVAIE
EADIVLFMVDGRAGLMAADKGIARHLRSREKTTVIVANKTDGIDADSAVGDFYSLGMGEIVPIAASHGRGINSLLEQVLL
PLVSDGLAEAEDEFAPWPDDEAEVLAREEEEEPFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIY
IPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIAVNK
WDGLSSETRDEVKEALDHRLGFIDFARVHFISALHGSGVGNLFESVNEAYQCATKRVSTALLTRIMRMAVDEHQPPLVRG
RRVKPKYAHAGGYNPPIVVIHGTQVKDLPDTYKRYLMNYFRRSLGIMGTPIRIQFNEGANPFAGRRNTLTPTQLRKRKRL
MSHIKKNK

Sequences:

>Translated_488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYCRAEWEGHEFIVIDTGGIDGTEEGVETRMAGQSLVAIE
EADIVLFMVDGRAGLMAADKGIARHLRSREKTTVIVANKTDGIDADSAVGDFYSLGMGEIVPIAASHGRGINSLLEQVLL
PLVSDGLAEAEDEFAPWPDDEAEVLAREEEEEPFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIY
IPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIAVNK
WDGLSSETRDEVKEALDHRLGFIDFARVHFISALHGSGVGNLFESVNEAYQCATKRVSTALLTRIMRMAVDEHQPPLVRG
RRVKPKYAHAGGYNPPIVVIHGTQVKDLPDTYKRYLMNYFRRSLGIMGTPIRIQFNEGANPFAGRRNTLTPTQLRKRKRL
MSHIKKNK
>Mature_488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYCRAEWEGHEFIVIDTGGIDGTEEGVETRMAGQSLVAIE
EADIVLFMVDGRAGLMAADKGIARHLRSREKTTVIVANKTDGIDADSAVGDFYSLGMGEIVPIAASHGRGINSLLEQVLL
PLVSDGLAEAEDEFAPWPDDEAEVLAREEEEEPFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIY
IPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIAVNK
WDGLSSETRDEVKEALDHRLGFIDFARVHFISALHGSGVGNLFESVNEAYQCATKRVSTALLTRIMRMAVDEHQPPLVRG
RRVKPKYAHAGGYNPPIVVIHGTQVKDLPDTYKRYLMNYFRRSLGIMGTPIRIQFNEGANPFAGRRNTLTPTQLRKRKRL
MSHIKKNK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=82.4489795918367, Blast_Score=799, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=39.5604395604396, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SODGM (Q2NS44)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455436.1
- ProteinModelPortal:   Q2NS44
- SMR:   Q2NS44
- STRING:   Q2NS44
- GeneID:   3866915
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1756
- NMPDR:   fig|343509.6.peg.3760
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- PhylomeDB:   Q2NS44
- ProtClustDB:   PRK00093
- BioCyc:   SGLO343509:SG1756-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54112; Mature: 54112

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYCRAEWEGHEFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEECCCC
DGTEEGVETRMAGQSLVAIEEADIVLFMVDGRAGLMAADKGIARHLRSREKTTVIVANKT
CCCHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCEEHHHHHHHHHHCCCCEEEEEEECC
DGIDADSAVGDFYSLGMGEIVPIAASHGRGINSLLEQVLLPLVSDGLAEAEDEFAPWPDD
CCCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
EAEVLAREEEEEPFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIY
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEE
IPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVIDAREGISDQD
EEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
LSLLGFILNSGRSLVIAVNKWDGLSSETRDEVKEALDHRLGFIDFARVHFISALHGSGVG
HHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
NLFESVNEAYQCATKRVSTALLTRIMRMAVDEHQPPLVRGRRVKPKYAHAGGYNPPIVVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
HGTQVKDLPDTYKRYLMNYFRRSLGIMGTPIRIQFNEGANPFAGRRNTLTPTQLRKRKRL
ECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
MSHIKKNK
HHHHHCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYCRAEWEGHEFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEECCCC
DGTEEGVETRMAGQSLVAIEEADIVLFMVDGRAGLMAADKGIARHLRSREKTTVIVANKT
CCCHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCEEHHHHHHHHHHCCCCEEEEEEECC
DGIDADSAVGDFYSLGMGEIVPIAASHGRGINSLLEQVLLPLVSDGLAEAEDEFAPWPDD
CCCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
EAEVLAREEEEEPFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIY
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEE
IPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVIDAREGISDQD
EEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
LSLLGFILNSGRSLVIAVNKWDGLSSETRDEVKEALDHRLGFIDFARVHFISALHGSGVG
HHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
NLFESVNEAYQCATKRVSTALLTRIMRMAVDEHQPPLVRGRRVKPKYAHAGGYNPPIVVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
HGTQVKDLPDTYKRYLMNYFRRSLGIMGTPIRIQFNEGANPFAGRRNTLTPTQLRKRKRL
ECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
MSHIKKNK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA