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The map label for this gene is mntH [H]

Identifier: 85059652

GI number: 85059652

Start: 2854608

End: 2855258

Strand: Reverse

Name: mntH [H]

Synonym: SG1674

Alternate gene names: 85059652

Gene position: 2855258-2854608 (Counterclockwise)

Preceding gene: 85059654

Following gene: 85059649

Centisome position: 68.45

GC content: 55.3

Gene sequence:

>651_bases
ATGGTGGACAGCAGTACTGCGGATAATGCCAACCGTGCCGCGAGAAAAGTGAAGCTTTCCTTACTCGGACCCGCTTTCAT
CGCCGCGATTGGCTATATCGATCCCGGTAACTTTGCCACCAATATTCAAGCGGGAGCCAGTTTTGGCTATCGGCTGCTGT
GGGTGGTGGTGTGGGCCAATATCATGGCGATGCTGATTCAGCTTCTGTCCGCCAAATTGGGCATTGCCACCGGCAAGAAC
CTGGACGAGCACATTCGCGATCGTTTTCCCCGTCCCGCGGTGTGGGCCTATTGGGTGCAGGCCGAAATTATCGCAATGGC
GACCGACCTGGCGGAATTTATCGGCGCCGCTATCGGCTTTAAAATGCTGCTCGGGGTGTCGTTGTTGCAGGGCGCCATCA
TTACCGGTATCGTTACCTTCCTGATATTAATGTTGCAAAATCGCGGCCAAAAACCGCTGGAAGTGGTGATAGGCGGCCTG
CTGTTATTTGTCGCCGCCGCCTATATCGCCGAGCTGTTTTATTCCCGCCCGGTGATAAAGGAATTAGGCGCCGGCGTGCT
GGGCGCCACCATCATGCCGCACATCATCTATCTTCACTCCTCGCTGACCCAGAACGGTAGGGAGCTGTGCCGAACGTTAT
TCCTCCACTAA

Upstream 100 bases:

>100_bases
TGCTATCGAAGAGATAAGTAGAATCGCTTTGAATGCATTTGATAATCATTATCATTTTTATGATATTTCATGAACATGTG
AGTTGATAAGGGTTATTGCT

Downstream 100 bases:

>100_bases
AACTGGAGTGGCTATCGCGATGACCATCGCCGGCTTCGTCAATATTGGCGATGATGGCGGCGGCATTTCATTTCAGCGGT
CATACCGGCATTGCCGATCT

Product: putative manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MVDSSTADNANRAARKVKLSLLGPAFIAAIGYIDPGNFATNIQAGASFGYRLLWVVVWANIMAMLIQLLSAKLGIATGKN
LDEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKMLLGVSLLQGAIITGIVTFLILMLQNRGQKPLEVVIGGL
LLFVAAAYIAELFYSRPVIKELGAGVLGATIMPHIIYLHSSLTQNGRELCRTLFLH

Sequences:

>Translated_216_residues
MVDSSTADNANRAARKVKLSLLGPAFIAAIGYIDPGNFATNIQAGASFGYRLLWVVVWANIMAMLIQLLSAKLGIATGKN
LDEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKMLLGVSLLQGAIITGIVTFLILMLQNRGQKPLEVVIGGL
LLFVAAAYIAELFYSRPVIKELGAGVLGATIMPHIIYLHSSLTQNGRELCRTLFLH
>Mature_216_residues
MVDSSTADNANRAARKVKLSLLGPAFIAAIGYIDPGNFATNIQAGASFGYRLLWVVVWANIMAMLIQLLSAKLGIATGKN
LDEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKMLLGVSLLQGAIITGIVTFLILMLQNRGQKPLEVVIGGL
LLFVAAAYIAELFYSRPVIKELGAGVLGATIMPHIIYLHSSLTQNGRELCRTLFLH

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=213, Percent_Identity=36.6197183098592, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI295293167, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI295293175, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI295293173, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI10835169, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI295293171, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI295293169, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI295293178, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1788736, Length=222, Percent_Identity=74.3243243243243, Blast_Score=330, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI71993856, Length=230, Percent_Identity=34.7826086956522, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193210616, Length=220, Percent_Identity=34.5454545454545, Blast_Score=126, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17569473, Length=200, Percent_Identity=33, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71999499, Length=209, Percent_Identity=32.0574162679426, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324450, Length=212, Percent_Identity=33.0188679245283, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323062, Length=210, Percent_Identity=34.7619047619048, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321841, Length=210, Percent_Identity=32.3809523809524, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45553443, Length=230, Percent_Identity=34.7826086956522, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24648607, Length=230, Percent_Identity=34.7826086956522, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281362176, Length=230, Percent_Identity=34.7826086956522, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24648609, Length=230, Percent_Identity=34.7826086956522, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 23438; Mature: 23438

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDSSTADNANRAARKVKLSLLGPAFIAAIGYIDPGNFATNIQAGASFGYRLLWVVVWAN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCHHHHHHHHHHHHHHH
IMAMLIQLLSAKLGIATGKNLDEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMLLGVSLLQGAIITGIVTFLILMLQNRGQKPLEVVIGGLLLFVAAAYIAELFYSRPVIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ELGAGVLGATIMPHIIYLHSSLTQNGRELCRTLFLH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDSSTADNANRAARKVKLSLLGPAFIAAIGYIDPGNFATNIQAGASFGYRLLWVVVWAN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCHHHHHHHHHHHHHHH
IMAMLIQLLSAKLGIATGKNLDEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMLLGVSLLQGAIITGIVTFLILMLQNRGQKPLEVVIGGLLLFVAAAYIAELFYSRPVIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ELGAGVLGATIMPHIIYLHSSLTQNGRELCRTLFLH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA