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The map label for this gene is dsbE [H]

Identifier: 85059612

GI number: 85059612

Start: 2793078

End: 2793533

Strand: Reverse

Name: dsbE [H]

Synonym: SG1634

Alternate gene names: 85059612

Gene position: 2793533-2793078 (Counterclockwise)

Preceding gene: 85059613

Following gene: 85059611

Centisome position: 66.97

GC content: 57.68

Gene sequence:

>456_bases
ATGAGCCGCAAACTGCTGTATATTCCCCTGGTGCTGTTTTTGCTGCTGGCGCTCGCCCTTACGGTGCAATTGGCGCACAA
TGCCCATGGCGACGATCCCACCCGGTTGGAGTCGGCGCTGATAGGAAAACCGTTACCGTCATTGACCCTGGCGTCCCTGG
ACGATCCCGGCAAGATTTACAGTCAAGCGCTTTTGCGCGACGCGCATCCCTGGTTGCTCAACGTCTGGGCCACCTGGTGT
CCCACCTGCCGCGCCGAGCATCAATTTCTCAACGGCCTTGCCGCCTGGGGCGTCAGGATCGCCGGCGTAAATTACAAAGA
CAGCCGTGCGAAGACAATGGCCTGGCTTAATACCCTAGGCAATTCCTATGCGCTAAGCATATTCGATGGCGACGGTATGC
TCGGACTGGATCTGGGCGTCTATGGCGCACCAGAGACGTTTCTCATCGATGGTTAG

Upstream 100 bases:

>100_bases
TGGGCGGTCTGTTTATGGTTGCCGGCGGGGTTTGCTGTCTGCTTGACCCGCACTACCGGGCGGCGAAGAAGGCCCGCCTG
ACGGGCAGCGGGGCGTCCTT

Downstream 100 bases:

>100_bases
GGGATCGTATGCTATCGCCACGCCGGCGATATGAACGCCCAGGTCTGGCGCCAGGACGTCGAGCCGCTGTATCGCCGGTA
TGGGGGGAGCAAAAATGAGG

Product: thiol:disulfide interchange protein DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MSRKLLYIPLVLFLLLALALTVQLAHNAHGDDPTRLESALIGKPLPSLTLASLDDPGKIYSQALLRDAHPWLLNVWATWC
PTCRAEHQFLNGLAAWGVRIAGVNYKDSRAKTMAWLNTLGNSYALSIFDGDGMLGLDLGVYGAPETFLIDG

Sequences:

>Translated_151_residues
MSRKLLYIPLVLFLLLALALTVQLAHNAHGDDPTRLESALIGKPLPSLTLASLDDPGKIYSQALLRDAHPWLLNVWATWC
PTCRAEHQFLNGLAAWGVRIAGVNYKDSRAKTMAWLNTLGNSYALSIFDGDGMLGLDLGVYGAPETFLIDG
>Mature_150_residues
SRKLLYIPLVLFLLLALALTVQLAHNAHGDDPTRLESALIGKPLPSLTLASLDDPGKIYSQALLRDAHPWLLNVWATWCP
TCRAEHQFLNGLAAWGVRIAGVNYKDSRAKTMAWLNTLGNSYALSIFDGDGMLGLDLGVYGAPETFLIDG

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=151, Percent_Identity=68.8741721854305, Blast_Score=221, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 16475; Mature: 16344

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKLLYIPLVLFLLLALALTVQLAHNAHGDDPTRLESALIGKPLPSLTLASLDDPGKIY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCHHHH
SQALLRDAHPWLLNVWATWCPTCRAEHQFLNGLAAWGVRIAGVNYKDSRAKTMAWLNTLG
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCC
NSYALSIFDGDGMLGLDLGVYGAPETFLIDG
CCEEEEEECCCCEEEEEECCCCCCCEEEECC
>Mature Secondary Structure 
SRKLLYIPLVLFLLLALALTVQLAHNAHGDDPTRLESALIGKPLPSLTLASLDDPGKIY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCHHHH
SQALLRDAHPWLLNVWATWCPTCRAEHQFLNGLAAWGVRIAGVNYKDSRAKTMAWLNTLG
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCC
NSYALSIFDGDGMLGLDLGVYGAPETFLIDG
CCEEEEEECCCCEEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]