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The map label for this gene is mtnU [H]

Identifier: 85059456

GI number: 85059456

Start: 2471424

End: 2472221

Strand: Reverse

Name: mtnU [H]

Synonym: SG1478

Alternate gene names: 85059456

Gene position: 2472221-2471424 (Counterclockwise)

Preceding gene: 85059457

Following gene: 85059453

Centisome position: 59.27

GC content: 49.87

Gene sequence:

>798_bases
TTGTTTACATTAGCTTTAGTACAAACAGATGCCTATTTGGGTGAAAAACGGAGAAATCTCGAACGGTTGCAGACATTTTG
CCATACCGCTAAAAAAGAAGGGGCCCAGCTCATTTGTTTTCCTGAATTGGCGACGACCGGCTATGCACCCACGCTATTGG
GCCCTGAATATCATGCATTGAGCGAAACACGACAGGGTGAAACAAACCGGATGTTCAGCGCGCTGGCAACAGAGCTGGGG
GTCATTATTGTTTGCGGTTTCATTGAACGCGATATGCAAACAGACGCCGTTTATAATGCCGCAGGCGTCTGGTTGCCGGG
GCAGGAAAGCTGGTTAGGGGTATTTAGAAAAATGCATCTTATCCAGGAAGAAAAACGCTGGTTCACGCCCGGCCAACAAC
TTCGGGTATTTGATACCCCCCTCGGACGCATCGGCGGTATGATATGTTATGACGCGGGATTCCCCGAAGTCGCTCGTAGT
CTGACGCTCAAACAGGCCGACTCTTTGCTCTTGTTATCTGCCTGGCCTGAAAAGGACAAGGATATATGGTATATTAACGG
CCCTTGCCGGGCGCTGGAAAATACTATTTATTTGGCCGCGGTCAATCGCTGGGGCAGAGAGGGTGATTGCCAGCTGTTTG
GCGGTAGTCAAATACTCAACCCACGTGGTCAAGTAATGGCAAGAGCGACGGAACACGCAGAGCAAATCCTTTATCATACC
ATCGATAAGCAAGTTCAGTCGGCCATTCGCCACACCTTGCCTTATTTGGCTGACCGGCAGCCCGAAAATTATCGGTAA

Upstream 100 bases:

>100_bases
TGCGCTGAATGCGATAGCCATCGCCGGCGCTCTATATTGGCTGTTGTCGCATCTTAAACATAATGATAGTAAACGCGTGT
CTGAGGGTGAGAGGTAACCA

Downstream 100 bases:

>100_bases
GTATTTCCCCACGCCGTGAATGCGGGCCCGGCACCCGAAAAAAGCGCGGGTGCCGGCCTGTTGTAGGATAATGCCGGCAT
AGCGCGCCGGATTTCCAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MFTLALVQTDAYLGEKRRNLERLQTFCHTAKKEGAQLICFPELATTGYAPTLLGPEYHALSETRQGETNRMFSALATELG
VIIVCGFIERDMQTDAVYNAAGVWLPGQESWLGVFRKMHLIQEEKRWFTPGQQLRVFDTPLGRIGGMICYDAGFPEVARS
LTLKQADSLLLLSAWPEKDKDIWYINGPCRALENTIYLAAVNRWGREGDCQLFGGSQILNPRGQVMARATEHAEQILYHT
IDKQVQSAIRHTLPYLADRQPENYR

Sequences:

>Translated_265_residues
MFTLALVQTDAYLGEKRRNLERLQTFCHTAKKEGAQLICFPELATTGYAPTLLGPEYHALSETRQGETNRMFSALATELG
VIIVCGFIERDMQTDAVYNAAGVWLPGQESWLGVFRKMHLIQEEKRWFTPGQQLRVFDTPLGRIGGMICYDAGFPEVARS
LTLKQADSLLLLSAWPEKDKDIWYINGPCRALENTIYLAAVNRWGREGDCQLFGGSQILNPRGQVMARATEHAEQILYHT
IDKQVQSAIRHTLPYLADRQPENYR
>Mature_265_residues
MFTLALVQTDAYLGEKRRNLERLQTFCHTAKKEGAQLICFPELATTGYAPTLLGPEYHALSETRQGETNRMFSALATELG
VIIVCGFIERDMQTDAVYNAAGVWLPGQESWLGVFRKMHLIQEEKRWFTPGQQLRVFDTPLGRIGGMICYDAGFPEVARS
LTLKQADSLLLLSAWPEKDKDIWYINGPCRALENTIYLAAVNRWGREGDCQLFGGSQILNPRGQVMARATEHAEQILYHT
IDKQVQSAIRHTLPYLADRQPENYR

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=274, Percent_Identity=27.7372262773723, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=29.3040293040293, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI297632350, Length=273, Percent_Identity=29.3040293040293, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=29.3040293040293, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1786412, Length=200, Percent_Identity=27, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557111, Length=274, Percent_Identity=25.5474452554745, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323383, Length=275, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355835, Length=278, Percent_Identity=26.2589928057554, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17933642, Length=264, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30055; Mature: 30055

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLALVQTDAYLGEKRRNLERLQTFCHTAKKEGAQLICFPELATTGYAPTLLGPEYHAL
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCCCHHHH
SETRQGETNRMFSALATELGVIIVCGFIERDMQTDAVYNAAGVWLPGQESWLGVFRKMHL
HHHCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHH
IQEEKRWFTPGQQLRVFDTPLGRIGGMICYDAGFPEVARSLTLKQADSLLLLSAWPEKDK
HHHHHHHCCCCCCEEEEECCHHHHCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCC
DIWYINGPCRALENTIYLAAVNRWGREGDCQLFGGSQILNPRGQVMARATEHAEQILYHT
CEEEECCCHHHHHCEEEEEEECCCCCCCCEEEECCCEEECCHHHHHHHHHHHHHHHHHHH
IDKQVQSAIRHTLPYLADRQPENYR
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFTLALVQTDAYLGEKRRNLERLQTFCHTAKKEGAQLICFPELATTGYAPTLLGPEYHAL
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCCCHHHH
SETRQGETNRMFSALATELGVIIVCGFIERDMQTDAVYNAAGVWLPGQESWLGVFRKMHL
HHHCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHH
IQEEKRWFTPGQQLRVFDTPLGRIGGMICYDAGFPEVARSLTLKQADSLLLLSAWPEKDK
HHHHHHHCCCCCCEEEEECCHHHHCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCC
DIWYINGPCRALENTIYLAAVNRWGREGDCQLFGGSQILNPRGQVMARATEHAEQILYHT
CEEEECCCHHHHHCEEEEEEECCCCCCCCEEEECCCEEECCHHHHHHHHHHHHHHHHHHH
IDKQVQSAIRHTLPYLADRQPENYR
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]