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The map label for this gene is asnC

Identifier: 85058993

GI number: 85058993

Start: 1677677

End: 1679077

Strand: Reverse

Name: asnC

Synonym: SG1015

Alternate gene names: 85058993

Gene position: 1679077-1677677 (Counterclockwise)

Preceding gene: 85058994

Following gene: 85058992

Centisome position: 40.25

GC content: 53.25

Gene sequence:

>1401_bases
ATGAGCGTAGTGCCTGTAGTCGATGTACTGCAAGGGCGCATGCCGGCTGACAGTGAAATCACTGTACAGGGTTGGGTGCG
TACCCGCCGGGATTCCAAAGCCGGAATCTCCTTTCTTGCCGTCTATGACGGTTCCTGCTTCGATCCCTTACAGGCTGTCA
TTAATAATACTCTGCCGAATTATCAGAACGACATTTTACGCCTGACCTCGGGTTGCTCCGTGTCGGTGACCGGTCGGGTG
GTCGAATCCCTGGGCGGTGGTCAGCGTTACGAAATTCAGGCCCAGGCAATTGAAGTGCTCGGCTGGGTGGACGATCCGGA
CACCTACCCCATGGCAGCCAAGCGTCACAGCGTGGAATATCTACGCGAGGTCGCTCATCTGCGGCCGCGCACCAACCTTA
TCGGAGCGGTGGCGCGGGTGCGTCATACCCTGGCGCAGGCCATTCACCGTTTCATGGACGAGCAAGGGTTTTTCTGGGTG
TCGACGCCGTTGATTACCGCTTCCGATACTGAAGGCGCCGGTGAAATGTTCCGCGTGTCCACCCTCGATCTGGAAAATCT
GCCGCGCACCCCCGACGGCAAAGTTAATTATGATGAAGATTTCTTCGGCAAAGAGGCCTTCCTGACGGTTTCGGGACAGT
TAAACGGTGAAAGTTACGCCTGCGCTTTGTCGAAAATCTACACCTTCGGCCCCACGTTCCGGGCGGAAAATTCCAATACC
AGCCGCCATCTCGCCGAATTCTGGATGGCCGAGCCAGAGGTCGCGTTCGCTACCCTGGACGATGCCGCCGGTTTAGCGGA
AGCCATGCTTAAATATGTGTTTCAGGCAGTATTGACCGAGCGGGCCGACGATATGCAATTCTTCGCCGAGCGGATCGACA
AAGAGGCAATAAATCGTCTGAAACAATTTATCAGTGCAGATTTTGCTCAAGTCGACTACACCAAGGCGGTAGAGATCCTG
CAAAACTGCGGTCAGACTTTTGAAAATCCGGTTTCCTGGGGCATTGACTTATCTTCGGAACATGAACGCTATCTAGCGGA
AAAACATTTTAAAGCGCCGGTGGTGGTGAAAAATTATCCCAAAGATATCAAGGCATTCTACATGCGGATGAACGACGATG
GCAAAACCGTCGCGGCCATGGATGTTCTGGCGCCCGGCATCGGTGAAATCATCGGCGGGTCACAGCGTGAAGAGCGTCTG
GACCGGCTGGACCAGCGTCTGGCGGAAATGGGACTTAATAAAGACGATTACTGGTGGTATCGGGATTTGCGTCGCTATGG
AACCGTTCCGCATTCAGGTTTTGGATTAGGTTTCGAGAGATTAATAGTGTATGTCACGGGAATGCAAAATATTCGTGATG
TAATACCCTTCCCGCGAAGTCCACGCAATGCCAATTTCTAA

Upstream 100 bases:

>100_bases
ATTTCCCCTTGTGGTCTTGCCGCCGCCAAGTAACATATTATGTTATGGTACGTTAGCGGGCCAAAAGCCTTTTCCTATTA
ACTGAGTAAGAGAGTATTTT

Downstream 100 bases:

>100_bases
AATCCAGCATTTAATATAAGAAAAACATATAAATACGACACCAAGGCCAGCTCTGCTGTCCTTAGTATGGTTTTAATGGA
TTGAAATAAAAGGATTTATT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSVVPVVDVLQGRMPADSEITVQGWVRTRRDSKAGISFLAVYDGSCFDPLQAVINNTLPNYQNDILRLTSGCSVSVTGRV
VESLGGGQRYEIQAQAIEVLGWVDDPDTYPMAAKRHSVEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFMDEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRTPDGKVNYDEDFFGKEAFLTVSGQLNGESYACALSKIYTFGPTFRAENSNT
SRHLAEFWMAEPEVAFATLDDAAGLAEAMLKYVFQAVLTERADDMQFFAERIDKEAINRLKQFISADFAQVDYTKAVEIL
QNCGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DRLDQRLAEMGLNKDDYWWYRDLRRYGTVPHSGFGLGFERLIVYVTGMQNIRDVIPFPRSPRNANF

Sequences:

>Translated_466_residues
MSVVPVVDVLQGRMPADSEITVQGWVRTRRDSKAGISFLAVYDGSCFDPLQAVINNTLPNYQNDILRLTSGCSVSVTGRV
VESLGGGQRYEIQAQAIEVLGWVDDPDTYPMAAKRHSVEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFMDEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRTPDGKVNYDEDFFGKEAFLTVSGQLNGESYACALSKIYTFGPTFRAENSNT
SRHLAEFWMAEPEVAFATLDDAAGLAEAMLKYVFQAVLTERADDMQFFAERIDKEAINRLKQFISADFAQVDYTKAVEIL
QNCGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DRLDQRLAEMGLNKDDYWWYRDLRRYGTVPHSGFGLGFERLIVYVTGMQNIRDVIPFPRSPRNANF
>Mature_465_residues
SVVPVVDVLQGRMPADSEITVQGWVRTRRDSKAGISFLAVYDGSCFDPLQAVINNTLPNYQNDILRLTSGCSVSVTGRVV
ESLGGGQRYEIQAQAIEVLGWVDDPDTYPMAAKRHSVEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFMDEQGFFWVS
TPLITASDTEGAGEMFRVSTLDLENLPRTPDGKVNYDEDFFGKEAFLTVSGQLNGESYACALSKIYTFGPTFRAENSNTS
RHLAEFWMAEPEVAFATLDDAAGLAEAMLKYVFQAVLTERADDMQFFAERIDKEAINRLKQFISADFAQVDYTKAVEILQ
NCGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERLD
RLDQRLAEMGLNKDDYWWYRDLRRYGTVPHSGFGLGFERLIVYVTGMQNIRDVIPFPRSPRNANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=43.3189655172414, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI4758762, Length=446, Percent_Identity=27.5784753363229, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI45439306, Length=346, Percent_Identity=29.7687861271676, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=84.9785407725322, Blast_Score=850, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=365, Percent_Identity=24.3835616438356, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789256, Length=341, Percent_Identity=23.7536656891496, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788173, Length=184, Percent_Identity=27.1739130434783, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=471, Percent_Identity=29.2993630573248, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=30.6976744186047, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17551876, Length=342, Percent_Identity=27.4853801169591, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=468, Percent_Identity=35.8974358974359, Blast_Score=277, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6321807, Length=455, Percent_Identity=30.7692307692308, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=352, Percent_Identity=26.7045454545455, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=36.2068965517241, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI19921528, Length=465, Percent_Identity=27.9569892473118, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=27.6967930029155, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SODGM (Q2NU85)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454695.1
- HSSP:   O57980
- ProteinModelPortal:   Q2NU85
- SMR:   Q2NU85
- STRING:   Q2NU85
- GeneID:   3866379
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1015
- NMPDR:   fig|343509.6.peg.2099
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   Q2NU85
- ProtClustDB:   PRK03932
- BioCyc:   SGLO343509:SG1015-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52499; Mature: 52368

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVPVVDVLQGRMPADSEITVQGWVRTRRDSKAGISFLAVYDGSCFDPLQAVINNTLPN
CCCCHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCC
YQNDILRLTSGCSVSVTGRVVESLGGGQRYEIQAQAIEVLGWVDDPDTYPMAAKRHSVEY
HHHHHHHHCCCCEEEEHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQAIHRFMDEQGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTPDGKVNYDEDFFGKEAFLTVSGQLNGESYACALSKIYTFGPTFRAENSNT
EECHHHCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCH
SRHLAEFWMAEPEVAFATLDDAAGLAEAMLKYVFQAVLTERADDMQFFAERIDKEAINRL
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KQFISADFAQVDYTKAVEILQNCGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERLDRLDQRLAEMGLNKDDYWWY
HHHHHHHEEECCCCCEEEHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
RDLRRYGTVPHSGFGLGFERLIVYVTGMQNIRDVIPFPRSPRNANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVVPVVDVLQGRMPADSEITVQGWVRTRRDSKAGISFLAVYDGSCFDPLQAVINNTLPN
CCCHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCC
YQNDILRLTSGCSVSVTGRVVESLGGGQRYEIQAQAIEVLGWVDDPDTYPMAAKRHSVEY
HHHHHHHHCCCCEEEEHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQAIHRFMDEQGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTPDGKVNYDEDFFGKEAFLTVSGQLNGESYACALSKIYTFGPTFRAENSNT
EECHHHCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCH
SRHLAEFWMAEPEVAFATLDDAAGLAEAMLKYVFQAVLTERADDMQFFAERIDKEAINRL
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KQFISADFAQVDYTKAVEILQNCGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERLDRLDQRLAEMGLNKDDYWWY
HHHHHHHEEECCCCCEEEHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
RDLRRYGTVPHSGFGLGFERLIVYVTGMQNIRDVIPFPRSPRNANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA