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The map label for this gene is fur

Identifier: 85058839

GI number: 85058839

Start: 1416708

End: 1417175

Strand: Reverse

Name: fur

Synonym: SG0861

Alternate gene names: 85058839

Gene position: 1417175-1416708 (Counterclockwise)

Preceding gene: 85058840

Following gene: 85058836

Centisome position: 33.98

GC content: 49.36

Gene sequence:

>468_bases
ATGACTGACAATAACATCGCCTTAAAGAAGGCCGGCCTGAAAGTGACCCTTCCCAGGCTCAAGATCCTGGAAGTGTTGCA
AGACCCGGAATGCCACCACGTCAGTGCGGAAGATCTGTATAAAAAGCTTATCGATATGGGTGAGGAAATCGGGCTGGCCA
CCGTTTACCGCGTACTCAACCAGTTCGATGATGCCGGTATTGTCACCCGCCACAATTTTGAGGGCGGCAAATCGGTTTTC
GAGCTCACCCAACAGCATCATCACGATCACCTTATTTGCCTGGATTGCGGCAAGGTCATCGAATTTCGCGATGAGTTTAT
TGAAGCGCGCCAGCGTGATATCGCGAAAAAGCACAATATCAAACTGACCAACCACAGTCTCTATATTTATGGCCATTGCG
CAGAGGGCGACTGCCGTGAAGATGAAACCCTGCATGATATAGATGATCCGCACGTCGTAAAATTCTGA

Upstream 100 bases:

>100_bases
CGAGTTCTATGATGAGACAGTGAACCATTTTTCGGGCCGACGATTGTTATAGGCTGTGTTAGCTTATAGCTTGATTATCA
AGTAACAGGACCAAACCCGC

Downstream 100 bases:

>100_bases
CCGCCAACACCTGGGCCGTCAGATCACGAGCGAACAAAGAGAAACCGCCGCCGGCGGTTTTTTTATTTGTTGAGGCTGTA
ACTGCCTGAGTCAACCTTAC

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTDNNIALKKAGLKVTLPRLKILEVLQDPECHHVSAEDLYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFRDEFIEARQRDIAKKHNIKLTNHSLYIYGHCAEGDCREDETLHDIDDPHVVKF

Sequences:

>Translated_155_residues
MTDNNIALKKAGLKVTLPRLKILEVLQDPECHHVSAEDLYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFRDEFIEARQRDIAKKHNIKLTNHSLYIYGHCAEGDCREDETLHDIDDPHVVKF
>Mature_154_residues
TDNNIALKKAGLKVTLPRLKILEVLQDPECHHVSAEDLYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFE
LTQQHHHDHLICLDCGKVIEFRDEFIEARQRDIAKKHNIKLTNHSLYIYGHCAEGDCREDETLHDIDDPHVVKF

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=146, Percent_Identity=89.041095890411, Blast_Score=270, Evalue=4e-74,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17842; Mature: 17710

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNNIALKKAGLKVTLPRLKILEVLQDPECHHVSAEDLYKKLIDMGEEIGLATVYRVLN
CCCCCEEEEECCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFRDEFIEARQRDIAKKHNI
HCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCE
KLTNHSLYIYGHCAEGDCREDETLHDIDDPHVVKF
EEECCEEEEEEECCCCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
TDNNIALKKAGLKVTLPRLKILEVLQDPECHHVSAEDLYKKLIDMGEEIGLATVYRVLN
CCCCEEEEECCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFRDEFIEARQRDIAKKHNI
HCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCE
KLTNHSLYIYGHCAEGDCREDETLHDIDDPHVVKF
EEECCEEEEEEECCCCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9055816 [H]