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The map label for this gene is nagA

Identifier: 85058793

GI number: 85058793

Start: 1375953

End: 1377095

Strand: Reverse

Name: nagA

Synonym: SG0815

Alternate gene names: 85058793

Gene position: 1377095-1375953 (Counterclockwise)

Preceding gene: 85058794

Following gene: 85058792

Centisome position: 33.01

GC content: 58.44

Gene sequence:

>1143_bases
ATGTATGCTTTAACCAACGGCCGCATCTATACCGGTAGCGAGATTCTGGATAACCACTCGCTCGTTATCGCAAACGGCGT
TATCGACGCCATTTGCCCCGCCGACAGCCTGCCCGCCGGCATTGAACGCCGCGATTTGGCCGGCGCCGCGCTGGCGCCCG
GTTTTATCGACCTGCAGCTTAACGGCTGCGGCGGCGTACAGTTCAACGACAGCCTGGACGCGCTGTCGGTCGAAACGCTG
GAAACGATGCAGGCCGCCAATCAGCGCTCCGGCTGCACCAGTTTCCTGCCGACCCTCATCACCAGCACCGATGACTATAT
GCGGCGGGCGGTGGAGGTCATGCGCGCTTACCTGGCGCAGCATAAACATCAGGCGCTGGGGTTGCATCTGGAAGGCCCCT
ACCTCAGCCCGGTCAAAAAAGGCACCCATGATCCGGCATTGATACGCGCACCGAGCGAAGAAATGGTGGTCTTCCTGTGC
GCTAACAGCGACGTGATAAGCAAGATGACCCTGGCTCCCGAACAGGTAGACGCGTCTGTTATCCGCCGGTTGTGCGACGC
CGGCATTCGCGTTTCTATTGGTCATTCCAATGCCACTTACCAGCAGGCCAAGGCGGGTTTCGCCGCCGGCATCAGCTTTA
CGACCCATCTGTTTAACGCCATGCCGCCGATGGTCGGGCGCGAACCGGGTGTTATCGGCGCCCTGTTCGACGCGCCGGAA
ATTTATTGCGGTATCATCGCCGACGGCCTGCATGTCAACTGGGCCAACATTCGTAACGCCAAACGCATTAAAGGCGATCG
CCTGATATTGGTCACGGATGCCACCGCCCCGGCCAGCGCGGAAAATATTGATCGGTTCATTTTCGCCGGCAAAACAATAT
ACTATCGCGATGGCCTTTGCGTGGATGAACACGGTACCCTTAGCGGCTCGGCGCTTACCATGATTGAAGCGGTACGTGGT
AGCGTAGAGTACGCCGGTATCGCATTGGACGAGGCGTTGCGCATGGCAACCCTTTACCCGGCACGGGCGCTGGGCGTGGA
CGCGCGGTTAGGGACGCTGACGGTCGGCAAAATCGCCAACTTAACCGCCTTCACCCACGATTATAAAATCAGTAAAACTA
TCGTTAACGGCGACGAAGTTTGA

Upstream 100 bases:

>100_bases
GAACCGTCTACCCAGGAATTGAAGATGAAAACGGTCAAATACTTCCGTGAACTGGAACAAGACAATCTGAACACCGCCGA
CTAACCTCCCGGAGCTGAAT

Downstream 100 bases:

>100_bases
CCATAAGCGAGTAAGCGATGACACCAGGCGGACAGACCCCGATAGGCAATATTGACCTTGTTAAACAGTTAAATAACGCG
GCGGTCTACCGTCTCATCGA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MYALTNGRIYTGSEILDNHSLVIANGVIDAICPADSLPAGIERRDLAGAALAPGFIDLQLNGCGGVQFNDSLDALSVETL
ETMQAANQRSGCTSFLPTLITSTDDYMRRAVEVMRAYLAQHKHQALGLHLEGPYLSPVKKGTHDPALIRAPSEEMVVFLC
ANSDVISKMTLAPEQVDASVIRRLCDAGIRVSIGHSNATYQQAKAGFAAGISFTTHLFNAMPPMVGREPGVIGALFDAPE
IYCGIIADGLHVNWANIRNAKRIKGDRLILVTDATAPASAENIDRFIFAGKTIYYRDGLCVDEHGTLSGSALTMIEAVRG
SVEYAGIALDEALRMATLYPARALGVDARLGTLTVGKIANLTAFTHDYKISKTIVNGDEV

Sequences:

>Translated_380_residues
MYALTNGRIYTGSEILDNHSLVIANGVIDAICPADSLPAGIERRDLAGAALAPGFIDLQLNGCGGVQFNDSLDALSVETL
ETMQAANQRSGCTSFLPTLITSTDDYMRRAVEVMRAYLAQHKHQALGLHLEGPYLSPVKKGTHDPALIRAPSEEMVVFLC
ANSDVISKMTLAPEQVDASVIRRLCDAGIRVSIGHSNATYQQAKAGFAAGISFTTHLFNAMPPMVGREPGVIGALFDAPE
IYCGIIADGLHVNWANIRNAKRIKGDRLILVTDATAPASAENIDRFIFAGKTIYYRDGLCVDEHGTLSGSALTMIEAVRG
SVEYAGIALDEALRMATLYPARALGVDARLGTLTVGKIANLTAFTHDYKISKTIVNGDEV
>Mature_380_residues
MYALTNGRIYTGSEILDNHSLVIANGVIDAICPADSLPAGIERRDLAGAALAPGFIDLQLNGCGGVQFNDSLDALSVETL
ETMQAANQRSGCTSFLPTLITSTDDYMRRAVEVMRAYLAQHKHQALGLHLEGPYLSPVKKGTHDPALIRAPSEEMVVFLC
ANSDVISKMTLAPEQVDASVIRRLCDAGIRVSIGHSNATYQQAKAGFAAGISFTTHLFNAMPPMVGREPGVIGALFDAPE
IYCGIIADGLHVNWANIRNAKRIKGDRLILVTDATAPASAENIDRFIFAGKTIYYRDGLCVDEHGTLSGSALTMIEAVRG
SVEYAGIALDEALRMATLYPARALGVDARLGTLTVGKIANLTAFTHDYKISKTIVNGDEV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=424, Percent_Identity=33.2547169811321, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI224922791, Length=421, Percent_Identity=33.2541567695962, Blast_Score=162, Evalue=7e-40,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=69.4736842105263, Blast_Score=559, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17553768, Length=353, Percent_Identity=33.4277620396601, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI19920392, Length=343, Percent_Identity=33.8192419825073, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281361140, Length=357, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40624; Mature: 40624

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTNGRIYTGSEILDNHSLVIANGVIDAICPADSLPAGIERRDLAGAALAPGFIDLQL
CEEEECCEEEECHHHHCCCCEEEECCCCHHHCCCCCCCCCCCHHHCCCHHHCCCEEEEEE
NGCGGVQFNDSLDALSVETLETMQAANQRSGCTSFLPTLITSTDDYMRRAVEVMRAYLAQ
CCCCCCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HKHQALGLHLEGPYLSPVKKGTHDPALIRAPSEEMVVFLCANSDVISKMTLAPEQVDASV
CCCHHEEEEECCCCCCHHHCCCCCCEEEECCCCCEEEEEECCCCHHHHHCCCHHHHHHHH
IRRLCDAGIRVSIGHSNATYQQAKAGFAAGISFTTHLFNAMPPMVGREPGVIGALFDAPE
HHHHHCCCCEEEECCCCCHHHHHHCCHHHCHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
IYCGIIADGLHVNWANIRNAKRIKGDRLILVTDATAPASAENIDRFIFAGKTIYYRDGLC
EEEEEEECCEEEEHHHCCCCHHCCCCEEEEEECCCCCCCHHHCCEEEEECCEEEEECCEE
VDEHGTLSGSALTMIEAVRGSVEYAGIALDEALRMATLYPARALGVDARLGTLTVGKIAN
ECCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCHHHHCCCCCCCEEEHHHHHC
LTAFTHDYKISKTIVNGDEV
EEEEECCEEEEEEEECCCCC
>Mature Secondary Structure
MYALTNGRIYTGSEILDNHSLVIANGVIDAICPADSLPAGIERRDLAGAALAPGFIDLQL
CEEEECCEEEECHHHHCCCCEEEECCCCHHHCCCCCCCCCCCHHHCCCHHHCCCEEEEEE
NGCGGVQFNDSLDALSVETLETMQAANQRSGCTSFLPTLITSTDDYMRRAVEVMRAYLAQ
CCCCCCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HKHQALGLHLEGPYLSPVKKGTHDPALIRAPSEEMVVFLCANSDVISKMTLAPEQVDASV
CCCHHEEEEECCCCCCHHHCCCCCCEEEECCCCCEEEEEECCCCHHHHHCCCHHHHHHHH
IRRLCDAGIRVSIGHSNATYQQAKAGFAAGISFTTHLFNAMPPMVGREPGVIGALFDAPE
HHHHHCCCCEEEECCCCCHHHHHHCCHHHCHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
IYCGIIADGLHVNWANIRNAKRIKGDRLILVTDATAPASAENIDRFIFAGKTIYYRDGLC
EEEEEEECCEEEEHHHCCCCHHCCCCEEEEEECCCCCCCHHHCCEEEEECCEEEEECCEE
VDEHGTLSGSALTMIEAVRGSVEYAGIALDEALRMATLYPARALGVDARLGTLTVGKIAN
ECCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCHHHHCCCCCCCEEEHHHHHC
LTAFTHDYKISKTIVNGDEV
EEEEECCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]